Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   GOM48_RS08340 Genome accession   NZ_CP046523
Coordinates   1661375..1662199 (-) Length   274 a.a.
NCBI ID   WP_001036766.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1656375..1667199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS08325 (GOM48_08265) amiA 1657411..1659390 (-) 1980 WP_000749717.1 peptide ABC transporter substrate-binding protein Regulator
  GOM48_RS08335 (GOM48_08275) - 1659903..1661234 (-) 1332 WP_000390050.1 hemolysin family protein -
  GOM48_RS08340 (GOM48_08280) endA 1661375..1662199 (-) 825 WP_001036766.1 DNA/RNA non-specific endonuclease Machinery gene
  GOM48_RS08345 (GOM48_08285) - 1662240..1662446 (-) 207 WP_000828205.1 DNA-directed RNA polymerase subunit beta -
  GOM48_RS08350 (GOM48_08290) murA 1662433..1663716 (-) 1284 WP_000411923.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  GOM48_RS08355 (GOM48_08295) - 1663739..1663969 (-) 231 WP_002892633.1 DUF1146 family protein -
  GOM48_RS08360 (GOM48_08300) sepM 1664025..1665062 (-) 1038 WP_000730769.1 SepM family pheromone-processing serine protease Regulator
  GOM48_RS08365 (GOM48_08305) coaD 1665046..1665534 (-) 489 WP_001280709.1 pantetheine-phosphate adenylyltransferase -
  GOM48_RS08370 (GOM48_08310) rsmD 1665524..1666063 (-) 540 WP_000706947.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  GOM48_RS08375 (GOM48_08315) asnA 1666128..1667120 (-) 993 WP_000747987.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29969.72 Da        Isoelectric Point: 9.9861

>NTDB_id=404939 GOM48_RS08340 WP_001036766.1 1661375..1662199(-) (endA) [Streptococcus oralis strain SOD]
MNKKTRQALIGLLIFLLLAAGSYYIKQMQLTSNTPKTKVSQKKQASEAPSQELAESVLTESVKNQIKGGLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKIKPVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKALDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTN

Nucleotide


Download         Length: 825 bp        

>NTDB_id=404939 GOM48_RS08340 WP_001036766.1 1661375..1662199(-) (endA) [Streptococcus oralis strain SOD]
ATGAACAAAAAAACGAGACAGGCTCTGATAGGGTTACTTATATTCTTACTCTTGGCTGCTGGAAGCTATTATATCAAGCA
GATGCAGTTGACATCAAACACGCCTAAAACCAAAGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCTAGTCAGGAGCTGG
CTGAAAGTGTCTTAACCGAGTCGGTCAAGAATCAAATAAAAGGTGGTCTAGAATGGAATGGGGCAGGTGCCTTTATTGTT
AATGGTAATAAAACCAATCTAGATGCTAAGGTTTCTAGCAAACCCTATGCGGATAATAAAATAAAACCAGTCGGGAAAGA
GACCGTCCCGACTGTTGCCAATGCTATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAGACTGGAAATGGAT
CCACCTCTTGGACGCCACCAGGATGGCATCAGGTCAAGAATCTAAAGGGAACCTATACACATGCAGTTGATAGAGGACAT
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACCAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCAAACCAAGCGCAGGCTGAGGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGCCTTGGACC
AGAATAAGAGAGTCCGTTATCGGGTGACGCTTCACTATGCGACAAATGAGGATCTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCGGATGGTGAATTGGAATTCAATGTCCTGATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGTCAAGTCACAGTGACAAACTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

89.011

99.635

0.887
  endA Streptococcus pneumoniae D39

89.011

99.635

0.887
  endA Streptococcus pneumoniae R6

89.011

99.635

0.887
  endA Streptococcus pneumoniae TIGR4

89.011

99.635

0.887

Multiple sequence alignment