Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HWU15_RS02295 Genome accession   NZ_CP058281
Coordinates   461188..463764 (+) Length   858 a.a.
NCBI ID   WP_237015796.1    Uniprot ID   -
Organism   Helicobacter pylori strain Hk711     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 456188..468764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWU15_RS02265 - 458373..458960 (-) 588 Protein_441 restriction endonuclease subunit S -
  HWU15_RS02270 - 459015..459803 (+) 789 WP_237015792.1 integrase -
  HWU15_RS02275 - 459907..460386 (+) 480 WP_165552789.1 hypothetical protein -
  HWU15_RS02280 comB2 460383..460667 (+) 285 WP_237015793.1 TrbC/VirB2 family protein Machinery gene
  HWU15_RS02285 comB3 460678..460941 (+) 264 WP_237015794.1 competence protein ComB Machinery gene
  HWU15_RS02290 - 460952..461188 (+) 237 WP_237015795.1 hypothetical protein -
  HWU15_RS02295 comB4 461188..463764 (+) 2577 WP_237015796.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  HWU15_RS02300 - 463766..463900 (+) 135 WP_041200005.1 hypothetical protein -
  HWU15_RS02305 - 463893..465026 (+) 1134 WP_237015797.1 VirB8/TrbF family protein -
  HWU15_RS02310 - 465023..466690 (+) 1668 WP_237015798.1 TrbG/VirB9 family P-type conjugative transfer protein -
  HWU15_RS02315 comB10 466687..467889 (+) 1203 WP_237015799.1 DNA type IV secretion system protein ComB10 Machinery gene

Sequence

Protein


Download         Length: 858 a.a.        Molecular weight: 98850.87 Da        Isoelectric Point: 8.7548

>NTDB_id=404303 HWU15_RS02295 WP_237015796.1 461188..463764(+) (comB4) [Helicobacter pylori strain Hk711]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETHSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGKDFHINPFSLEDSPSNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNSQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKYFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLA

Nucleotide


Download         Length: 2577 bp        

>NTDB_id=404303 HWU15_RS02295 WP_237015796.1 461188..463764(+) (comB4) [Helicobacter pylori strain Hk711]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACTTATTCTAT
GACAGAGGAATGCAATATTTTAGGTTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAGGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACACAATTTGAAAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAAAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCCATTCAAATACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCATGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCTAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCTAATTCATGGGGGGATATGCCTTTATCTGTTTTCAAGAACCTAGACCATAGTC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGGCAT
ACCATGATTATAGGAGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGCGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGTA
AAGACTTTCATATCAATCCTTTTTCATTAGAGGATAGCCCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCTCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTCAGCAACCAAGAATTACCACTTCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCTTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCCTATTATGTCTTTCATAAAATGATTGATAGAGCCTTGAGAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGATATTAACCAGCTTAGTGAAGTGAGAAACTCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AATATTTTTTAGAAAACACCGCCGTTAATGAATACAAGGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAACACTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTGCCTAA

Domains

Predicted by InterProScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(214-412)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(437-504)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

46.849

98.019

0.459