Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SPYALAB49_RS05595 Genome accession   NC_017596
Coordinates   1111263..1111925 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes Alab49     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1106263..1116925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYALAB49_RS10170 (SPYALAB49_001143) - 1106826..1107059 (-) 234 WP_002983979.1 hypothetical protein -
  SPYALAB49_RS05580 (SPYALAB49_001144) sodA 1107226..1107831 (-) 606 WP_002983977.1 superoxide dismutase SodA -
  SPYALAB49_RS05585 (SPYALAB49_001145) holA 1107928..1108968 (-) 1041 WP_011054659.1 DNA polymerase III subunit delta -
  SPYALAB49_RS05590 (SPYALAB49_001146) comEC/celB 1109039..1111282 (-) 2244 WP_014635565.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SPYALAB49_RS05595 (SPYALAB49_001147) comEA/celA/cilE 1111263..1111925 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  SPYALAB49_RS05600 (SPYALAB49_001148) - 1112125..1112865 (-) 741 WP_014635566.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  SPYALAB49_RS05605 (SPYALAB49_001149) - 1112983..1113759 (+) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  SPYALAB49_RS05610 (SPYALAB49_001150) - 1113749..1114027 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  SPYALAB49_RS05615 (SPYALAB49_001151) - 1114051..1116051 (-) 2001 WP_002994363.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=40408 SPYALAB49_RS05595 WP_002995626.1 1111263..1111925(-) (comEA/celA/cilE) [Streptococcus pyogenes Alab49]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=40408 SPYALAB49_RS05595 WP_002995626.1 1111263..1111925(-) (comEA/celA/cilE) [Streptococcus pyogenes Alab49]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTTTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAATAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405

Multiple sequence alignment