Detailed information NTG0403435

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GL189_RS09360
• Genome accession: NZ_CP046360
• Coordinates: 1831711..1832721 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 574
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1826711..1837721

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL189_RS09335 (GL189_09495)	-	1826776..1827990 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
GL189_RS09340 (GL189_09500)	-	1828146..1828439 (-)	294	WP_000977366.1	hypothetical protein	-
GL189_RS09345 (GL189_09505)	-	1828602..1829054 (+)	453	WP_000079148.1	universal stress protein	-
GL189_RS09350 (GL189_09510)	-	1829089..1830477 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GL189_RS09355 (GL189_09515)	-	1830543..1831505 (+)	963	WP_001124777.1	asparaginase	-
GL189_RS09360 (GL189_09520)	ccpA	1831711..1832721 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
GL189_RS09365 (GL189_09525)	-	1833146..1833745 (-)	600	WP_000866719.1	response regulator transcription factor	-
GL189_RS09370 (GL189_09530)	-	1833747..1834844 (-)	1098	WP_000893546.1	sensor histidine kinase	-
GL189_RS09375 (GL189_09535)	-	1834844..1835581 (-)	738	WP_000832834.1	ABC transporter permease	-
GL189_RS09380 (GL189_09540)	-	1835583..1836467 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GL189_RS09385 (GL189_09545)	-	1836454..1836648 (-)	195	WP_000820180.1	hypothetical protein	-
GL189_RS09390 (GL189_09550)	-	1836645..1836851 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=403435 GL189_RS09360 WP_000990607.1 1831711..1832721(-) (ccpA) [Streptococcus pneumoniae strain 574]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=403435 GL189_RS09360 WP_000990607.1 1831711..1832721(-) (ccpA) [Streptococcus pneumoniae strain 574]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568