Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   GL189_RS09135 Genome accession   NZ_CP046360
Coordinates   1785373..1785993 (-) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae strain 574     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1780373..1790993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL189_RS09110 (GL189_09270) recA 1780750..1781916 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  GL189_RS09115 (GL189_09275) cinA 1781971..1783227 (-) 1257 WP_000642706.1 competence/damage-inducible protein A Machinery gene
  GL189_RS09120 (GL189_09280) brpA 1783312..1784328 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  GL189_RS09125 (GL189_09285) - 1784336..1784854 (-) 519 WP_024477661.1 GNAT family N-acetyltransferase -
  GL189_RS09130 (GL189_09290) tsaE 1784844..1785287 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  GL189_RS09135 (GL189_09295) comM 1785373..1785993 (-) 621 WP_000839909.1 hypothetical protein Regulator
  GL189_RS09140 (GL189_09300) - 1786376..1787239 (-) 864 WP_024477662.1 helix-turn-helix domain-containing protein -
  GL189_RS09145 (GL189_09305) - 1787428..1787598 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  GL189_RS09150 (GL189_09310) - 1788048..1790063 (+) 2016 WP_000732385.1 DUF1430 domain-containing protein -
  GL189_RS09155 (GL189_09315) - 1790065..1790697 (+) 633 WP_000571415.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=403432 GL189_RS09135 WP_000839909.1 1785373..1785993(-) (comM) [Streptococcus pneumoniae strain 574]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=403432 GL189_RS09135 WP_000839909.1 1785373..1785993(-) (comM) [Streptococcus pneumoniae strain 574]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364

Multiple sequence alignment