Detailed information NTG0403424

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: GL189_RS08745
• Genome accession: NZ_CP046360
• Coordinates: 1726824..1727891 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159556.1
• Uniprot ID: A0A0B7LLF7
• Organism: Streptococcus pneumoniae strain 574
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1721824..1732891

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL189_RS08720 (GL189_08890)	treR	1722202..1722912 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
GL189_RS08725 (GL189_08895)	-	1722945..1723748 (-)	804	WP_024477717.1	ABC transporter ATP-binding protein	-
GL189_RS08730 (GL189_08900)	-	1723761..1724654 (-)	894	WP_024477718.1	ABC transporter permease	-
GL189_RS08735 (GL189_08905)	-	1724666..1725268 (-)	603	WP_024477719.1	ABC transporter substrate-binding protein	-
GL189_RS08740 (GL189_08910)	amiF	1725887..1726813 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
GL189_RS08745 (GL189_08915)	amiE	1726824..1727891 (-)	1068	WP_000159556.1	ABC transporter ATP-binding protein	Regulator
GL189_RS08750 (GL189_08920)	amiD	1727900..1728826 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
GL189_RS08755 (GL189_08925)	amiC	1728826..1730322 (-)	1497	WP_000759903.1	ABC transporter permease	Regulator
GL189_RS08760 (GL189_08930)	amiA3	1730389..1732368 (-)	1980	WP_000742232.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39504.11 Da
• Isoelectric Point: 4.8764

>NTDB_id=403424 GL189_RS08745 WP_000159556.1 1726824..1727891(-) (amiE) [Streptococcus pneumoniae strain 574]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=403424 GL189_RS08745 WP_000159556.1 1726824..1727891(-) (amiE) [Streptococcus pneumoniae strain 574]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTGACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGAACTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0B7LLF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541