Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GL189_RS01775 Genome accession   NZ_CP046360
Coordinates   341534..342223 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 574     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 336534..347223
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL189_RS01750 (GL189_01820) gpsB 336643..336972 (+) 330 WP_000146522.1 cell division regulator GpsB -
  GL189_RS01760 (GL189_01830) - 337458..338615 (+) 1158 WP_000711372.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  GL189_RS01765 (GL189_01835) mapZ 338628..340022 (+) 1395 WP_032495864.1 cell division site-positioning protein MapZ -
  GL189_RS01770 (GL189_01840) gndA 340098..341522 (+) 1425 WP_000158795.1 NADP-dependent phosphogluconate dehydrogenase -
  GL189_RS01775 (GL189_01845) covR 341534..342223 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  GL189_RS01780 (GL189_01850) cbpC 342321..343337 (+) 1017 WP_061714028.1 choline-binding protein CbpC -
  GL189_RS01785 (GL189_01855) - 343456..344688 (-) 1233 WP_023935619.1 MFS transporter -
  GL189_RS01790 (GL189_01860) - 344731..345318 (-) 588 WP_050072454.1 lanthionine synthetase LanC family protein -
  GL189_RS11095 (GL189_01865) - 345218..345607 (-) 390 WP_016397728.1 lanthionine synthetase LanC family protein -
  GL189_RS11100 - 346219..346386 (+) 168 Protein_359 transposase -
  GL189_RS11105 - 346426..346548 (+) 123 Protein_360 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=403391 GL189_RS01775 WP_000518011.1 341534..342223(+) (covR) [Streptococcus pneumoniae strain 574]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=403391 GL189_RS01775 WP_000518011.1 341534..342223(+) (covR) [Streptococcus pneumoniae strain 574]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment