Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HUS69_RS09305 Genome accession   NZ_CP056073
Coordinates   1960409..1961065 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC50     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1955409..1966065
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUS69_RS09275 (HUS69_09285) dcyD 1956288..1957274 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  HUS69_RS09280 (HUS69_09290) tcyL 1957289..1957957 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HUS69_RS09285 (HUS69_09295) tcyN 1957954..1958706 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HUS69_RS09290 (HUS69_09300) sdiA 1958936..1959658 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  HUS69_RS09295 (HUS69_09305) yecF 1959726..1959950 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HUS69_RS09300 (HUS69_09310) yecU 1959937..1960113 (-) 177 WP_000590344.1 protein YecU -
  HUS69_RS23730 - 1960151..1960267 (-) 117 WP_001302039.1 hypothetical protein -
  HUS69_RS09305 (HUS69_09315) letA 1960409..1961065 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HUS69_RS09310 (HUS69_09320) uvrC 1961062..1962894 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HUS69_RS09315 (HUS69_09325) pgsA 1962951..1963499 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HUS69_RS09335 (HUS69_09345) yecA 1964149..1964814 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=403253 HUS69_RS09305 WP_000611335.1 1960409..1961065(+) (letA) [Escherichia coli strain EC50]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=403253 HUS69_RS09305 WP_000611335.1 1960409..1961065(+) (letA) [Escherichia coli strain EC50]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment