Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   MARKY_RS03900 Genome accession   NC_015387
Coordinates   744392..745306 (-) Length   304 a.a.
NCBI ID   WP_013703570.1    Uniprot ID   F2NM48
Organism   Marinithermus hydrothermalis DSM 14884     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 739392..750306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MARKY_RS03880 (Marky_0764) - 740992..741402 (+) 411 WP_013703566.1 NADH-quinone oxidoreductase subunit 15 -
  MARKY_RS03885 (Marky_0765) - 741566..742954 (+) 1389 WP_013703567.1 leucine-rich repeat protein -
  MARKY_RS03890 (Marky_0766) - 742959..743759 (-) 801 WP_245526792.1 cyclase family protein -
  MARKY_RS03895 (Marky_0767) - 743895..744320 (-) 426 WP_013703569.1 disulfide oxidoreductase -
  MARKY_RS03900 (Marky_0768) pilA 744392..745306 (-) 915 WP_013703570.1 signal recognition particle-docking protein FtsY Machinery gene
  MARKY_RS03905 (Marky_0769) gltX 745303..746748 (-) 1446 WP_013703571.1 glutamate--tRNA ligase -
  MARKY_RS03910 (Marky_0770) - 746768..747568 (-) 801 WP_013703572.1 undecaprenyl-diphosphate phosphatase -
  MARKY_RS03915 (Marky_0771) rpsI 747649..748041 (-) 393 WP_013703573.1 30S ribosomal protein S9 -
  MARKY_RS03920 (Marky_0772) rplM 748041..748475 (-) 435 WP_013703574.1 50S ribosomal protein L13 -

Sequence

Protein


Download         Length: 304 a.a.        Molecular weight: 32709.74 Da        Isoelectric Point: 8.0615

>NTDB_id=40318 MARKY_RS03900 WP_013703570.1 744392..745306(-) (pilA) [Marinithermus hydrothermalis DSM 14884]
MSWFQRLKEGLKKTSQAIAQAVPWGGDPEEVLEELEFALIAADVGVEATQEILEEVRQSGKKDLREAVKQSLVLQLEPDA
RRAKLRKLGFTPNAKKAVVEPKGRVVLMVGVNGVGKTTTIAKLGRYYRQHGRSVMFCAGDTFRAAGGAQLGLWGERLGIP
VIQGPEGSDPGALAFDAAQARKARGIDLLFVDTAGRLHTKHNLMEELKKIKRAIDKADPGEPGEVWLVLDAVTGQNGLQQ
AKRFHEAVGLTGVIVTKLDGTAKGGVLVPIVRELGVPIRFIGVGEGPDDLQPFDAGEFVEALLG

Nucleotide


Download         Length: 915 bp        

>NTDB_id=40318 MARKY_RS03900 WP_013703570.1 744392..745306(-) (pilA) [Marinithermus hydrothermalis DSM 14884]
ATGAGCTGGTTCCAGCGCCTCAAGGAAGGCCTCAAAAAGACGAGCCAGGCGATCGCGCAGGCCGTGCCGTGGGGCGGCGA
CCCGGAGGAGGTGCTCGAGGAGCTCGAGTTCGCCCTGATCGCGGCGGACGTGGGGGTGGAGGCCACCCAGGAGATCCTGG
AGGAGGTGCGTCAGTCCGGGAAGAAGGACCTCCGGGAGGCCGTGAAGCAAAGCCTGGTTCTGCAGCTCGAGCCGGACGCT
CGCCGGGCGAAGCTCCGGAAGCTGGGGTTCACGCCGAACGCGAAGAAGGCCGTGGTGGAGCCCAAGGGCCGGGTCGTGCT
GATGGTGGGCGTGAACGGGGTGGGTAAGACCACTACGATCGCGAAGCTCGGCCGGTACTACCGTCAGCACGGCCGGAGCG
TGATGTTCTGCGCGGGGGACACCTTCCGCGCGGCGGGCGGGGCCCAGCTGGGGCTTTGGGGCGAGCGGCTCGGCATTCCG
GTCATCCAGGGACCGGAGGGGTCGGACCCCGGCGCGCTCGCCTTTGACGCCGCGCAGGCCCGCAAGGCGCGCGGGATCGA
CTTGCTTTTTGTGGACACCGCCGGCCGCCTGCACACCAAGCACAACCTGATGGAGGAGCTGAAGAAGATCAAACGGGCGA
TCGACAAGGCAGATCCCGGCGAACCCGGCGAGGTCTGGCTCGTGTTGGACGCGGTGACGGGACAGAACGGCCTGCAACAA
GCGAAGCGGTTTCACGAAGCGGTCGGGCTCACGGGGGTGATCGTCACCAAGCTCGACGGCACCGCGAAAGGTGGCGTGCT
CGTCCCGATCGTGCGGGAGCTGGGCGTCCCCATCCGTTTCATCGGCGTGGGTGAGGGGCCGGACGACCTCCAACCCTTCG
ACGCCGGGGAGTTCGTAGAGGCCCTTTTGGGATAG

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(105-304)

SRP54-type protein, helical bundle domain (SRP54_N)

(29-65)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F2NM48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

48.726

100

0.503

Multiple sequence alignment