Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   SALIVA_RS08220 Genome accession   NC_017595
Coordinates   1823836..1825941 (-) Length   701 a.a.
NCBI ID   WP_014634941.1    Uniprot ID   -
Organism   Streptococcus salivarius JIM8777     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1818836..1830941
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVA_RS08195 (SALIVA_1673) pptB 1819181..1820215 (-) 1035 WP_371748832.1 ABC transporter permease Regulator
  SALIVA_RS08200 (SALIVA_1674) pptA 1820215..1820946 (-) 732 WP_014634937.1 ABC transporter ATP-binding protein Regulator
  SALIVA_RS08205 (SALIVA_1675) - 1821011..1821430 (+) 420 WP_014634938.1 HIT family protein -
  SALIVA_RS08210 (SALIVA_1676) - 1821427..1821726 (+) 300 WP_014634939.1 hypothetical protein -
  SALIVA_RS10625 (SALIVA_1677) - 1821907..1822074 (-) 168 WP_014634940.1 hypothetical protein -
  SALIVA_RS08215 (SALIVA_1678) - 1822649..1823257 (-) 609 WP_002884297.1 DUF4230 domain-containing protein -
  SALIVA_RS10815 (SALIVA_1680) - 1823275..1823400 (-) 126 WP_002884447.1 hypothetical protein -
  SALIVA_RS08220 (SALIVA_1681) clpE 1823836..1825941 (-) 2106 WP_014634941.1 AAA family ATPase Regulator
  SALIVA_RS08225 (SALIVA_1682) - 1826667..1826921 (-) 255 WP_014634942.1 Txe/YoeB family addiction module toxin -
  SALIVA_RS08230 (SALIVA_1683) - 1826925..1827179 (-) 255 WP_013991075.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  SALIVA_RS08235 (SALIVA_1684) - 1827321..1828412 (-) 1092 WP_014634944.1 nucleotidyltransferase -
  SALIVA_RS08240 (SALIVA_1685) - 1828419..1829159 (-) 741 WP_014634945.1 class I SAM-dependent methyltransferase -
  SALIVA_RS08245 (SALIVA_1686) rsfS 1829364..1829717 (-) 354 WP_014632696.1 ribosome silencing factor -
  SALIVA_RS08250 (SALIVA_1687) yqeK 1829741..1830331 (-) 591 WP_014634946.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77363.30 Da        Isoelectric Point: 4.7718

>NTDB_id=40318 SALIVA_RS08220 WP_014634941.1 1823836..1825941(-) (clpE) [Streptococcus salivarius JIM8777]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPSNEGEAVNPTQHQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTADLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=40318 SALIVA_RS08220 WP_014634941.1 1823836..1825941(-) (clpE) [Streptococcus salivarius JIM8777]
ATGAACAACAACTTTAACAATATGGACGATCTTTTCAATCAATTGATGGGGAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTAGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACATCAAGGTAAAGGACCTAAACAAGATGGTATTCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGACGCTGGTGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCTC
AAGCTATCGTTAATGGTGATGTCCCAGCTGCTATCAAGAACAAAGAAATCATCTCAATTGATATTTCTGGACTTGAAGCT
GGTACGCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAATATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGCGATGGCCAAGGGTCTAAAGGTCTTGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAGGATGAATACCGTAACACTATCTTGAAG
AACGCTGCTCTTGCTCGTCGTTTCAACGAAGTTAAGGTTAATGCTCCTTCTGCTGAAGATACCTTCAAGATTCTCCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCAGTAGATTTCTCTGTCC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCGGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGCAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAGTCTGTAGAACGTATGACTGGTATTCCAGTGTCACAAATGGGTGCAACTGAT
ATCGAACGTTTGAAAGATATGGGTCACCGTTTGCAAACTAAAGTTATCGGTCAAGATAAAGCCGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATTGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGATGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCTGGCTTTGGTTACGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGACGAAGTCATGGGTGTTCGTCCACTCCGCCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(257-351)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

46.648

100

0.466
  clpC Lactococcus lactis subsp. cremoris KW2

49.002

92.867

0.455
  clpE Streptococcus pneumoniae D39

48.678

91.726

0.447
  clpE Streptococcus pneumoniae R6

48.678

91.726

0.447
  clpE Streptococcus pneumoniae TIGR4

48.678

91.726

0.447
  clpE Streptococcus pneumoniae Rx1

48.678

91.726

0.447
  clpC Bacillus subtilis subsp. subtilis str. 168

45.007

95.72

0.431
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.089

92.867

0.391
  clpC Streptococcus pneumoniae TIGR4

43.087

88.73

0.382
  clpC Streptococcus pneumoniae Rx1

43.087

88.73

0.382
  clpC Streptococcus pneumoniae D39

43.087

88.73

0.382
  clpC Streptococcus thermophilus LMD-9

43.436

88.017

0.382
  clpC Streptococcus thermophilus LMG 18311

42.973

88.302

0.379
  clpC Streptococcus mutans UA159

42.332

89.301

0.378

Multiple sequence alignment