Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GL185_RS05675 Genome accession   NZ_CP046357
Coordinates   1139107..1139796 (-) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 525     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1134107..1144796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL185_RS11410 - 1134782..1134904 (-) 123 Protein_1131 hypothetical protein -
  GL185_RS11415 - 1134944..1135111 (-) 168 Protein_1132 transposase -
  GL185_RS11420 (GL185_05720) - 1135723..1136112 (+) 390 WP_016397728.1 lanthionine synthetase LanC family protein -
  GL185_RS05660 (GL185_05725) - 1136012..1136599 (+) 588 WP_050072454.1 lanthionine synthetase LanC family protein -
  GL185_RS05665 (GL185_05730) - 1136642..1137874 (+) 1233 WP_023935619.1 MFS transporter -
  GL185_RS05670 (GL185_05735) cbpC 1137993..1139009 (-) 1017 WP_024477741.1 choline-binding protein CbpC -
  GL185_RS05675 (GL185_05740) covR 1139107..1139796 (-) 690 WP_000518011.1 response regulator transcription factor Regulator
  GL185_RS05680 (GL185_05745) gndA 1139808..1141232 (-) 1425 WP_000158795.1 NADP-dependent phosphogluconate dehydrogenase -
  GL185_RS05685 (GL185_05750) mapZ 1141308..1142702 (-) 1395 WP_032495864.1 mid-cell-anchored protein MapZ -
  GL185_RS05690 (GL185_05755) - 1142715..1143872 (-) 1158 WP_000711372.1 class I SAM-dependent RNA methyltransferase -
  GL185_RS05700 (GL185_05765) gpsB 1144358..1144687 (-) 330 WP_000146522.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=403171 GL185_RS05675 WP_000518011.1 1139107..1139796(-) (covR) [Streptococcus pneumoniae strain 525]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=403171 GL185_RS05675 WP_000518011.1 1139107..1139796(-) (covR) [Streptococcus pneumoniae strain 525]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment