Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   GL184_RS01590 Genome accession   NZ_CP046356
Coordinates   305885..306505 (+) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae strain 521     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 300885..311505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL184_RS01570 (GL184_01595) - 301181..301813 (-) 633 WP_000571415.1 ABC transporter ATP-binding protein -
  GL184_RS01575 (GL184_01600) - 301815..303830 (-) 2016 WP_000732385.1 DUF1430 domain-containing protein -
  GL184_RS01580 (GL184_01605) - 304280..304450 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  GL184_RS01585 (GL184_01610) - 304639..305502 (+) 864 WP_024477662.1 helix-turn-helix domain-containing protein -
  GL184_RS01590 (GL184_01615) comM 305885..306505 (+) 621 WP_000839909.1 hypothetical protein Regulator
  GL184_RS01595 (GL184_01620) tsaE 306591..307034 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  GL184_RS01600 (GL184_01625) - 307024..307542 (+) 519 WP_024477661.1 GNAT family N-acetyltransferase -
  GL184_RS01605 (GL184_01630) brpA 307550..308566 (+) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  GL184_RS01610 (GL184_01635) cinA 308651..309907 (+) 1257 WP_000642706.1 competence/damage-inducible protein A Machinery gene
  GL184_RS01615 (GL184_01640) recA 309962..311128 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=403098 GL184_RS01590 WP_000839909.1 305885..306505(+) (comM) [Streptococcus pneumoniae strain 521]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=403098 GL184_RS01590 WP_000839909.1 305885..306505(+) (comM) [Streptococcus pneumoniae strain 521]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364

Multiple sequence alignment