Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SALIVA_RS07330 Genome accession   NC_017595
Coordinates   1644801..1645445 (-) Length   214 a.a.
NCBI ID   WP_002884791.1    Uniprot ID   -
Organism   Streptococcus salivarius JIM8777     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1639801..1650445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVA_RS07305 (SALIVA_1491) - 1641877..1642875 (-) 999 WP_014634808.1 NAD(P)/FAD-dependent oxidoreductase -
  SALIVA_RS07310 (SALIVA_1492) trmD 1642877..1643596 (-) 720 WP_002886864.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  SALIVA_RS07315 (SALIVA_1493) rimM 1643586..1644104 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  SALIVA_RS07330 (SALIVA_1496) vraR 1644801..1645445 (-) 645 WP_002884791.1 response regulator transcription factor Regulator
  SALIVA_RS07335 (SALIVA_1497) - 1645435..1646445 (-) 1011 WP_013990239.1 sensor histidine kinase -
  SALIVA_RS07340 (SALIVA_1498) liaF 1646442..1647140 (-) 699 WP_014634809.1 cell wall-active antibiotics response protein LiaF -
  SALIVA_RS07345 (SALIVA_1499) - 1647303..1648061 (-) 759 WP_014634810.1 potassium channel family protein -
  SALIVA_RS07350 (SALIVA_1500) stkP/pknB 1648209..1650083 (-) 1875 WP_014634811.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23977.31 Da        Isoelectric Point: 4.5814

>NTDB_id=40302 SALIVA_RS07330 WP_002884791.1 1644801..1645445(-) (vraR) [Streptococcus salivarius JIM8777]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAGNGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPDLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=40302 SALIVA_RS07330 WP_002884791.1 1644801..1645445(-) (vraR) [Streptococcus salivarius JIM8777]
ATGTCGAATAAGATTAATGTGATTTTGGTCGATGACCATGAGATGGTCCGTTTGGGACTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTCGTTGGAGAGGCAGGGAATGGTCGAGAGGGTGTTGATCTTGCCTTGGAACTGCGACCAGATGTCG
TCGTTATGGACCTTGTTATGCCTGAATTAGATGGTGTTCAAGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCCAAG
ATTTTGGTTTTGACTAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGAGCCAAAGGCTATATGCTTAA
AACCAGCAGTGCGGCAGAGATTCTCAATAGTATCCGTAAGGTTTACCGTGGTGAAGAAGCTATCGAAACTGAGGTGGACA
ATAAGATTAAATACCATGATAGCCATCCGGACCTACACGATGACTTGACGGCACGTGAACGTGATATCTTGGCGCTTTTG
GCTAAGGGCTATGACAATCAAACCATTGCTAACGAGTTATTTATTTCATTGAAGACCGTTAAAACTCACGTGTCTAATAT
CCTTGGAAAACTCAATGTTGATGACCGTACTCAGGCTGTCGTTTATGCTTTTAGACATCATTTGGTTTCGCAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment