Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   FOB91_RS01755 Genome accession   NZ_CP046328
Coordinates   360186..361415 (-) Length   409 a.a.
NCBI ID   WP_008808666.1    Uniprot ID   A0AAP2K4Q6
Organism   Streptococcus gordonii strain FDAARGOS_683     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 356127..383697 360186..361415 within 0


Gene organization within MGE regions


Location: 356127..383697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOB91_RS01730 (FOB91_01730) - 356127..356867 (-) 741 WP_012000544.1 esterase family protein -
  FOB91_RS01735 (FOB91_01735) - 356917..357741 (-) 825 WP_041789678.1 alpha/beta hydrolase -
  FOB91_RS01740 (FOB91_01740) - 357835..358632 (-) 798 WP_012000546.1 formate/nitrite transporter family protein -
  FOB91_RS01745 (FOB91_01745) - 358760..359449 (-) 690 WP_012000547.1 glucosaminidase domain-containing protein -
  FOB91_RS01750 (FOB91_01750) yihA 359583..360176 (-) 594 WP_012000548.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  FOB91_RS01755 (FOB91_01755) clpX 360186..361415 (-) 1230 WP_008808666.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  FOB91_RS01765 (FOB91_01765) - 361624..362136 (-) 513 WP_012000549.1 dihydrofolate reductase -
  FOB91_RS01770 (FOB91_01770) - 362289..362783 (-) 495 WP_012000550.1 hypothetical protein -
  FOB91_RS01775 (FOB91_01775) - 362914..363753 (-) 840 WP_012000551.1 thymidylate synthase -
  FOB91_RS01780 (FOB91_01780) - 363852..364811 (-) 960 WP_012000552.1 ROK family glucokinase -
  FOB91_RS01785 (FOB91_01785) - 364986..365831 (-) 846 WP_012000553.1 alpha/beta hydrolase -
  FOB91_RS01790 (FOB91_01790) - 365899..367111 (-) 1213 Protein_356 IS3 family transposase -
  FOB91_RS01795 (FOB91_01795) cshB 367224..374102 (-) 6879 WP_012000554.1 LPXTG-anchored fibrillar adhesin CshB -
  FOB91_RS01800 (FOB91_01800) - 374280..374882 (-) 603 WP_012000555.1 lysozyme family protein -
  FOB91_RS01805 (FOB91_01805) - 374882..375856 (-) 975 WP_012000556.1 nucleoid-associated protein -
  FOB91_RS01810 (FOB91_01810) glyA 375858..377120 (-) 1263 WP_012000557.1 serine hydroxymethyltransferase -
  FOB91_RS01815 (FOB91_01815) - 377168..377758 (-) 591 WP_041789683.1 L-threonylcarbamoyladenylate synthase -
  FOB91_RS01820 (FOB91_01820) prmC 377751..378581 (-) 831 WP_012000559.1 peptide chain release factor N(5)-glutamine methyltransferase -
  FOB91_RS01825 (FOB91_01825) prfA 378581..379660 (-) 1080 WP_012000560.1 peptide chain release factor 1 -
  FOB91_RS01830 (FOB91_01830) - 379693..380268 (-) 576 WP_008808654.1 thymidine kinase -
  FOB91_RS01835 (FOB91_01835) - 380390..380572 (+) 183 WP_001117401.1 4-oxalocrotonate tautomerase -
  FOB91_RS01840 (FOB91_01840) - 380685..381950 (-) 1266 WP_041789886.1 nucleobase:cation symporter-2 family protein -
  FOB91_RS01845 (FOB91_01845) - 381952..382533 (-) 582 WP_012000562.1 xanthine phosphoribosyltransferase -
  FOB91_RS01850 (FOB91_01850) guaC 382714..383697 (-) 984 WP_012000563.1 GMP reductase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45650.21 Da        Isoelectric Point: 4.4870

>NTDB_id=402659 FOB91_RS01755 WP_008808666.1 360186..361415(-) (clpX) [Streptococcus gordonii strain FDAARGOS_683]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=402659 FOB91_RS01755 WP_008808666.1 360186..361415(-) (clpX) [Streptococcus gordonii strain FDAARGOS_683]
ATGCCTACAAATCGTAATGAAGAGATGATGGTATATTGTTCATTCTGTGGGAAGAACCAAGATGAAGTTCAAAAGATTAT
TGCGGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCACAAGAAATTATCCGTGAAGAATTAGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGCCAAGAGCGT
GCTAAAAGAGCGCTAGCTGTAGCGGTATATAATCACTACAAGCGCATTAATTTTCACGATAGTCGTGAAGAAGATGATGT
TGAATTGCAAAAATCAAATATCTTAATGATTGGTCCAACGGGTTCTGGAAAAACTTTTCTTGCTCAAACCTTGGCTAGAA
GTTTAAATGTACCTTTTGCGATTGCTGATGCGACAGCTTTAACAGAGGCTGGTTATGTCGGAGAAGACGTTGAAAATATC
CTTTTAAAACTTTTACAGGCGGCTGATTTCAATATTGAACGTGCAGAACGCGGAATCATATACGTAGATGAGATTGATAA
GATCGCTAAAAAGAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAGGCTCTCTTAAAAATTA
TTGAGGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAACATCCGCAGCAAGAAATGATTCAGGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGGATTGAAGAAATTGTAAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATCGATGAAAACGAGTCCTACATGCAAGCTATTATTGCTGAAGATATTCAAAAATTTG
GAATTATTCCTGAATTAATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGATGACTTGGTTCGTATT
CTTCGTGAGCCTAAGAATGCTTTGGTTAAACAATACCAGGCTCTCTTGTCTTACGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGTGCTCGCGGTCTACGTTCTATCATCGAAGAAA
CCATGATGGATGTGATGTTCGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCCGAATTACTAAAGAAGCTGTTGATGGT
ACGGATAAACCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.575

100

0.856
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57

Multiple sequence alignment