Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SOR_RS07985 Genome accession   NC_015291
Coordinates   1587648..1588337 (-) Length   229 a.a.
NCBI ID   WP_000518001.1    Uniprot ID   A0A1X1GYE0
Organism   Streptococcus oralis Uo5     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1582648..1593337
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SOR_RS07965 (SOR_1629) - 1583599..1584606 (-) 1008 WP_000562392.1 phosphomevalonate kinase -
  SOR_RS07970 (SOR_1630) mvaD 1584593..1585546 (-) 954 WP_000375376.1 diphosphomevalonate decarboxylase -
  SOR_RS07975 (SOR_1631) mvk 1585528..1586406 (-) 879 WP_000159501.1 mevalonate kinase -
  SOR_RS07980 (SOR_1632) cbpC 1586528..1587547 (-) 1020 WP_000670354.1 choline-binding protein CbpC -
  SOR_RS07985 (SOR_1633) covR 1587648..1588337 (-) 690 WP_000518001.1 DNA-binding response regulator Regulator
  SOR_RS07990 (SOR_1634) gndA 1588349..1589773 (-) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  SOR_RS07995 (SOR_1635) mapZ 1589849..1591294 (-) 1446 WP_000039243.1 cell division site-positioning protein MapZ -
  SOR_RS08000 (SOR_1636) - 1591299..1592465 (-) 1167 WP_000711360.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  SOR_RS08005 (SOR_1638) gpsB 1592951..1593280 (-) 330 WP_000146523.1 cell division regulator GpsB -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26751.89 Da        Isoelectric Point: 7.4648

>NTDB_id=40211 SOR_RS07985 WP_000518001.1 1587648..1588337(-) (covR) [Streptococcus oralis Uo5]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNAHLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=40211 SOR_RS07985 WP_000518001.1 1587648..1588337(-) (covR) [Streptococcus oralis Uo5]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCTTGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTCCAGACGGACTATGACTTGATTTTACTGAATG
CTCATCTGGGGGATATGACGGCCCAGGATTTTGCAGACAAGCTGAGTCGGACAAAACCAGCCTCAGTGATTATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATAATCTAGTAGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTCATTGACCAGCACTGTAGTCAGATGAAGGTTC
CAACGTCTTATCGCAACCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAATATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAACAGTTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGACGTAAAAGGTCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X1GYE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment