Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   HUT19_RS18085 Genome accession   NZ_CP054916
Coordinates   4191853..4192911 (+) Length   352 a.a.
NCBI ID   WP_176187005.1    Uniprot ID   -
Organism   Streptomyces sp. NA02950     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4186853..4197911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HUT19_RS18070 (HUT19_18070) - 4187260..4188123 (+) 864 WP_176181480.1 hypothetical protein -
  HUT19_RS18075 (HUT19_18075) - 4188181..4189992 (-) 1812 WP_176181481.1 sigma-70 family RNA polymerase sigma factor -
  HUT19_RS18080 (HUT19_18080) radA/sms 4190174..4191607 (+) 1434 WP_176181482.1 DNA repair protein RadA Machinery gene
  HUT19_RS18085 (HUT19_18085) disA 4191853..4192911 (+) 1059 WP_176187005.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  HUT19_RS18090 (HUT19_18090) - 4193003..4193848 (-) 846 WP_176181483.1 hypothetical protein -
  HUT19_RS18095 (HUT19_18095) - 4194088..4195011 (+) 924 WP_254885635.1 A/G-specific adenine glycosylase -
  HUT19_RS18100 (HUT19_18100) - 4195238..4195849 (+) 612 WP_176181484.1 SigE family RNA polymerase sigma factor -
  HUT19_RS18105 (HUT19_18105) - 4195876..4196538 (+) 663 WP_254885636.1 hypothetical protein -
  HUT19_RS18110 (HUT19_18110) cseB 4196548..4197255 (+) 708 WP_176181486.1 two-component system response regulator CseB -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38236.00 Da        Isoelectric Point: 5.0869

>NTDB_id=402022 HUT19_RS18085 WP_176187005.1 4191853..4192911(+) (disA) [Streptomyces sp. NA02950]
MRASLSAVAPGTALRDGLERVLRGNTGGLIVLGTDRTMESLCTGGFVLDVEFTATRLRELCKLDGALILDKDITKIVRAG
VQLVPDASIPTEETGTRHRTAQRVSIQTGFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVEPERELVVRDYVPEPTAKRT
RTVADALAELDRLTHAELVELPIVARALGYSGSPETLDAAVSPRGFRLLAKVPRLPGAIIERLVEHFGGLQKLLAASVDD
LQMVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=402022 HUT19_RS18085 WP_176187005.1 4191853..4192911(+) (disA) [Streptomyces sp. NA02950]
ATGCGCGCCTCCCTGAGCGCCGTCGCGCCCGGCACGGCACTGCGCGACGGCCTGGAGCGGGTGCTCCGGGGCAATACGGG
CGGGCTGATCGTGCTCGGCACGGACCGGACCATGGAGTCGCTGTGCACCGGCGGCTTCGTCCTCGACGTCGAGTTCACCG
CGACCCGGCTGCGCGAGCTGTGCAAGCTGGACGGCGCGCTGATCCTCGACAAGGACATCACCAAGATCGTGCGGGCGGGG
GTGCAGCTCGTCCCGGACGCGTCGATCCCCACCGAGGAGACCGGCACCCGCCACCGCACCGCGCAGCGCGTCTCGATCCA
GACCGGCTTCCCGGTGGTCTCCGTCAGCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGCAGCGGCGGGTCCTGG
AGGACTCCGCGGCGATCCTCTCCCGCGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTCCGGCTGGACGAGGTC
GCGGGCACCCTCTCCGCCCTGGAGATCGAGGACCTGGTCACGGTCCGGGACGTGAGCGCGGTCGCGCAGCGTCTCGAGAT
GGTCCGGCGCATCGCCACCGAGATCGCCGAGTACGTGGTCGAGCTGGGCACCGACGGGCGGCTGCTCTCCCTCCAGCTCG
ACGAGCTGATCGCGGGTGTGGAGCCGGAGCGCGAGCTCGTGGTGCGGGACTACGTCCCCGAGCCGACCGCCAAGCGCACC
CGCACCGTCGCCGACGCGCTCGCCGAGCTGGACCGGCTGACCCATGCCGAGCTGGTCGAACTGCCGATCGTGGCGCGGGC
ACTGGGCTACAGCGGCTCGCCCGAGACGCTGGACGCGGCGGTTTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGC
GGCTCCCGGGCGCCATCATCGAGCGGCTGGTGGAGCACTTCGGCGGACTGCAGAAGCTGCTGGCCGCCAGCGTGGACGAC
CTCCAGATGGTGGACGGCGTGGGCGAGGCGCGGGCGCGCTCGGTACGCGAGGGGCTCTCCCGGCTGGCCGAGTCCTCGAT
CCTGGAGCGCTACGTCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(302-337)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

46.532

98.295

0.457