Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   GKC13_RS07695 Genome accession   NZ_CP046134
Coordinates   1487760..1489079 (-) Length   439 a.a.
NCBI ID   WP_207560143.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain MAG_rmk202_sterm     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1482760..1494079
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKC13_RS07685 (GKC13_07780) raiA 1486490..1487038 (-) 549 WP_011680772.1 ribosome-associated translation inhibitor RaiA -
  GKC13_RS07690 (GKC13_07785) - 1487117..1487779 (-) 663 WP_014607994.1 ComF family protein -
  GKC13_RS07695 (GKC13_07790) comFA/cflA 1487760..1489079 (-) 1320 WP_207560143.1 DEAD/DEAH box helicase Machinery gene
  GKC13_RS07700 (GKC13_07795) - 1489134..1489760 (+) 627 WP_011225515.1 YigZ family protein -
  GKC13_RS07705 (GKC13_07800) cysK 1489862..1490788 (+) 927 WP_014607992.1 cysteine synthase A -
  GKC13_RS07710 (GKC13_07805) - 1490955..1491615 (-) 661 Protein_1524 CBS and ACT domain-containing protein -
  GKC13_RS07715 (GKC13_07810) - 1491751..1492461 (-) 711 WP_014607989.1 ABC transporter ATP-binding protein -
  GKC13_RS07720 (GKC13_07815) - 1492461..1493225 (-) 765 WP_002949740.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50538.65 Da        Isoelectric Point: 9.5841

>NTDB_id=401530 GKC13_RS07695 WP_207560143.1 1487760..1489079(-) (comFA/cflA) [Streptococcus thermophilus strain MAG_rmk202_sterm]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIIDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPCFFWQGRLQKSLTSDKLPRPLIHQIKKQRKSNFPLLIFFPNIALGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFSQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=401530 GKC13_RS07695 WP_207560143.1 1487760..1489079(-) (comFA/cflA) [Streptococcus thermophilus strain MAG_rmk202_sterm]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGATTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATGATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTATTGACGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTTTAGT
CCTTCCTTGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAGCGATAAGCTTCCAAGGCCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTCCCCAATATAGCATTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAATTGTCAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTTCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAGGAGGGTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae D39

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae R6

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae TIGR4

54.756

98.178

0.538
  comFA/cflA Streptococcus mitis NCTC 12261

54.419

97.95

0.533
  comFA/cflA Streptococcus mitis SK321

53.488

97.95

0.524
  comFA Lactococcus lactis subsp. cremoris KW2

46.429

95.672

0.444
  comFA Latilactobacillus sakei subsp. sakei 23K

36.782

99.089

0.364

Multiple sequence alignment