Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   GKC25_RS14180 Genome accession   NZ_CP046128
Coordinates   2765888..2766529 (-) Length   213 a.a.
NCBI ID   WP_058013793.1    Uniprot ID   A0A2G8IV23
Organism   Bacillus pumilus strain V17C11     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2760888..2771529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GKC25_RS14145 (GKC25_14000) - 2762000..2762431 (+) 432 WP_034317176.1 Na(+)/H(+) antiporter subunit B -
  GKC25_RS14150 (GKC25_14005) - 2762431..2762772 (+) 342 WP_003213576.1 Na(+)/H(+) antiporter subunit C -
  GKC25_RS14155 (GKC25_14010) - 2762765..2764243 (+) 1479 WP_034659818.1 Na+/H+ antiporter subunit D -
  GKC25_RS14160 (GKC25_14015) - 2764250..2764729 (+) 480 WP_034659819.1 Na+/H+ antiporter subunit E -
  GKC25_RS14165 (GKC25_14020) - 2764729..2765010 (+) 282 WP_008345849.1 Na(+)/H(+) antiporter subunit F1 -
  GKC25_RS14170 (GKC25_14025) mnhG 2764994..2765368 (+) 375 WP_003213369.1 monovalent cation/H(+) antiporter subunit G -
  GKC25_RS14175 (GKC25_14030) - 2765475..2765864 (-) 390 WP_034659822.1 hotdog fold thioesterase -
  GKC25_RS14180 (GKC25_14035) comA 2765888..2766529 (-) 642 WP_058013793.1 response regulator transcription factor Regulator
  GKC25_RS14185 (GKC25_14040) comP 2766610..2768922 (-) 2313 WP_095285837.1 ATP-binding protein Regulator
  GKC25_RS14190 (GKC25_14045) comX 2768979..2769146 (-) 168 WP_081311380.1 competence pheromone ComX -
  GKC25_RS14195 (GKC25_14050) - 2769143..2770057 (-) 915 WP_034659828.1 polyprenyl synthetase family protein -
  GKC25_RS14200 (GKC25_14055) degQ 2770209..2770349 (-) 141 WP_003213123.1 degradation enzyme regulation protein DegQ Regulator
  GKC25_RS14205 (GKC25_14060) - 2770855..2771208 (+) 354 WP_095285836.1 inner spore coat protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 24154.55 Da        Isoelectric Point: 4.5688

>NTDB_id=401398 GKC25_RS14180 WP_058013793.1 2765888..2766529(-) (comA) [Bacillus pumilus strain V17C11]
MKKILVIDDHPAVMEGTKSILESDQQLSVDCLSPDAEAAFLKTHDFSIYDVILMDLNLGDINGMDIAKQILETNQQVKII
IYTGYEVDDYFEEAIRAGLHGAISKTETKDKIIEYIHRTLQGEVVIQLSYLKKLISQQQEKPEQAQQTDHELLTERECLI
LREVEKGYTNQEIADVLHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSESVL

Nucleotide


Download         Length: 642 bp        

>NTDB_id=401398 GKC25_RS14180 WP_058013793.1 2765888..2766529(-) (comA) [Bacillus pumilus strain V17C11]
ATGAAGAAGATATTGGTCATTGATGATCATCCGGCTGTCATGGAAGGGACAAAAAGCATATTAGAATCAGATCAGCAGCT
ATCAGTCGATTGTTTAAGTCCTGATGCAGAAGCCGCCTTTTTAAAGACGCATGACTTTTCCATCTATGATGTGATTTTGA
TGGATTTAAATCTCGGGGATATCAATGGAATGGACATTGCGAAACAAATTCTAGAAACCAACCAGCAAGTGAAAATTATC
ATTTATACAGGGTATGAAGTAGATGATTATTTTGAAGAGGCCATTCGGGCTGGATTGCACGGTGCAATTAGTAAAACAGA
GACAAAAGACAAAATTATTGAATACATACACCGCACATTGCAAGGAGAAGTTGTCATTCAGCTATCCTATTTAAAGAAAT
TAATTTCACAGCAGCAAGAAAAGCCAGAACAGGCGCAGCAGACCGATCATGAGCTGTTAACAGAGCGAGAGTGTTTGATC
CTCAGAGAAGTGGAAAAAGGATACACGAACCAAGAGATTGCCGATGTGCTTCATTTGAGCAAACGCTCGATTGAATACAG
CTTGACGTCCATCTTTAATAAGCTGAATGTTGGCTCTCGAACCGAAGCGGTGTTAATTGCAAAATCTGAAAGTGTGCTGT
AA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2G8IV23

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

71.495

100

0.718

Multiple sequence alignment