Detailed information NTG0400531

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: GJS33_RS07000
• Genome accession: NZ_CP046041
• Coordinates: 1492959..1494311 (-)
• Length: 450 a.a.
• NCBI ID: WP_012677636.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain AZ-45470
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1490748..1492007	1492959..1494311	flank	952

Gene organization within MGE regions

Location: 1490748..1494311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJS33_RS06990 (GJS33_06990)	-	1490748..1492007 (+)	1260	WP_014622678.1	ISL3-like element ISSeq1 family transposase	-
GJS33_RS06995 (GJS33_06995)	vicX	1492146..1492955 (-)	810	WP_021320992.1	MBL fold metallo-hydrolase	Regulator
GJS33_RS07000 (GJS33_07000)	vicK	1492959..1494311 (-)	1353	WP_012677636.1	cell wall metabolism sensor histidine kinase VicK	Regulator

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51541.94 Da
• Isoelectric Point: 5.5557

>NTDB_id=400531 GJS33_RS07000 WP_012677636.1 1492959..1494311(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=400531 GJS33_RS07000 WP_012677636.1 1492959..1494311(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain AZ-45470]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCATAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAACGACCTATCAGAT
GTTTTTCGTCTGACCCATGAAAACCTTGCCCAAGAGAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGTGAGCAGG
CGCTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCACCTTACACCTACCGAGAGCTGGTCTCAAAGACACCGATT
GTGACCTTAAATCGTCGTAATGACACAGGAGAGTTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTAGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAGGAGCGTGAGCGCAGACTCTTTGTCT
CAAATGTTAGCCATGAGCTTCGCACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATAGCCCCAAGCTTTATAAAGGTCTCACTAGACGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACCAGTACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCTGA
TGGTGGGAAAATTATCGTAAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGTTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCGCAGGGGGGTACCGGC
TTAGGGCTGGCTATTGCCAAAGAAATTATCAAGCAGCACCGAGGCTTTATCTGGGCTAAGAGTGACTATGGCAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (95-197)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	73.671	92	0.678
micB	Streptococcus pneumoniae Cp1015	66.824	94.444	0.631