Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FOC72_RS10930 Genome accession   NZ_CP054570
Coordinates   2244855..2246798 (+) Length   647 a.a.
NCBI ID   WP_032914008.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2239855..2251798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS10910 (FOC72_10910) argR 2240649..2241086 (+) 438 WP_002894105.1 arginine repressor -
  FOC72_RS10915 (FOC72_10915) hexA 2241165..2243714 (+) 2550 WP_002894103.1 DNA mismatch repair protein MutS Machinery gene
  FOC72_RS10920 (FOC72_10920) - 2243763..2244233 (-) 471 WP_002894101.1 DUF3021 family protein -
  FOC72_RS10925 (FOC72_10925) brsR 2244230..2244670 (-) 441 WP_002894100.1 LytTR family DNA-binding domain-containing protein Regulator
  FOC72_RS10930 (FOC72_10930) hexB 2244855..2246798 (+) 1944 WP_032914008.1 DNA mismatch repair endonuclease MutL Machinery gene
  FOC72_RS10935 (FOC72_10935) - 2246834..2247355 (-) 522 WP_002894097.1 RDD family protein -
  FOC72_RS10940 (FOC72_10940) - 2247339..2247845 (-) 507 WP_032914287.1 helix-turn-helix domain-containing protein -
  FOC72_RS10945 (FOC72_10945) ruvA 2248015..2248605 (+) 591 WP_032914006.1 Holliday junction branch migration protein RuvA Machinery gene
  FOC72_RS10950 (FOC72_10950) - 2248615..2249187 (+) 573 WP_002894092.1 DNA-3-methyladenine glycosylase I -
  FOC72_RS10955 (FOC72_10955) - 2249197..2250045 (-) 849 WP_002894091.1 helix-turn-helix domain-containing protein -
  FOC72_RS10960 (FOC72_10960) - 2250435..2250773 (+) 339 WP_002894090.1 hypothetical protein -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73289.41 Da        Isoelectric Point: 5.0232

>NTDB_id=400221 FOC72_RS10930 WP_032914008.1 2244855..2246798(+) (hexB) [Streptococcus sanguinis strain FDAARGOS_770]
MSKIIELPEILANQIAAGEVIERPSSVVKELVENSIDAGASQITIEIEEAGLKTIQVTDNGEGIDHEDVPLALRRHATSK
IKKQADLFRIRTLGFRGEAIPSIASVSRFTIETATEAGQHGTLLVAQGGEIEEHEPTSSPVGTKIKIEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLISDGREMTRTAGSGNLRQAIAGIYGLATAKKMVEISASDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVINIQIDPYLADVNVHPTKQEVRISKERELMALISQ
AIATSLKEQDLIPDALENLAKSTVKRATKPEQTSLPLKENRLYYDKEQNDFFLKPQVAEQQLSFEESAEPIHEATNEKAE
PQPTSVKFAERKPVSYDQLDHPELDQVSLERAVDKLEQEEKSSFPELEYFGQMHGTYLFAQGKGGLYIIDQHAAQERVKY
EYYREKIGDVDNSQQQLLVPYIFEFPADDILRIKQRMELLEDAGIFLEEYGANQFILREHPIWFKEEEIEAGIYEMCDML
LLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLLFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=400221 FOC72_RS10930 WP_032914008.1 2244855..2246798(+) (hexB) [Streptococcus sanguinis strain FDAARGOS_770]
ATGTCAAAAATTATCGAACTTCCAGAAATTCTAGCCAATCAGATTGCGGCCGGTGAAGTCATTGAGCGGCCTAGCAGCGT
GGTCAAGGAGCTAGTGGAAAATTCAATTGATGCGGGTGCAAGTCAGATTACCATCGAAATAGAGGAGGCTGGACTCAAGA
CTATCCAGGTAACGGATAATGGTGAAGGCATAGACCACGAAGATGTCCCTCTGGCACTTCGCCGCCATGCTACCAGTAAA
ATCAAGAAACAAGCGGATCTCTTTCGGATTCGGACACTGGGTTTTCGTGGTGAGGCCATTCCTTCCATTGCTTCTGTTTC
GCGTTTCACCATTGAGACAGCGACTGAAGCCGGCCAGCACGGAACCCTGCTAGTTGCCCAAGGCGGTGAGATTGAAGAGC
ATGAGCCTACCAGCAGTCCAGTGGGAACGAAAATCAAGATTGAAGATCTCTTCTTCAATACTCCAGCCCGGCTCAAGTAT
ATGAAGAGCCAGCAGGCTGAGCTGTCCCATATCGTTGATGTGATTAATCGGCTTAGTCTGGCCCATCCGGAAGTGGCTTT
CACCCTTATCAGTGACGGCCGCGAAATGACACGGACTGCCGGCAGTGGTAATCTGCGTCAGGCTATTGCAGGAATCTATG
GTTTGGCAACAGCTAAGAAAATGGTGGAAATCTCTGCATCGGATTTGGATTTTGAAGTGAGTGGCTATGTCAGTTTGCCT
GAGCTGACTCGTGCGAATCGGAATTATATTACCATTCTCATCAACGGCCGCTACATTAAGAATTTCCTGCTCAATCGCGC
TATTTTGGACGGCTACGGCAGCAAGCTTATGGTAGGTCGCTTTCCACTCGCGGTCATCAATATTCAGATTGACCCCTATC
TGGCCGATGTCAATGTCCATCCGACCAAGCAAGAGGTGCGAATTTCTAAAGAGCGGGAACTCATGGCCTTGATTTCGCAA
GCTATTGCAACCAGTCTCAAGGAGCAGGATCTTATCCCGGATGCTTTGGAAAATCTAGCCAAATCAACTGTTAAGCGTGC
GACTAAGCCCGAACAGACCAGCCTCCCGCTGAAAGAAAATCGCCTCTACTACGATAAGGAGCAGAATGACTTCTTCCTCA
AGCCACAGGTGGCCGAGCAGCAGCTATCCTTCGAAGAATCAGCGGAGCCTATTCATGAAGCGACAAATGAAAAAGCAGAG
CCACAACCAACTTCGGTCAAATTTGCAGAGAGAAAGCCAGTTAGCTATGACCAACTAGACCATCCAGAGCTTGATCAGGT
CAGTCTGGAGCGGGCTGTGGATAAGTTGGAGCAGGAAGAGAAGTCAAGCTTCCCAGAGTTAGAATATTTCGGCCAGATGC
ATGGCACTTATCTCTTTGCTCAGGGCAAGGGTGGTCTTTACATTATTGACCAGCATGCTGCCCAGGAGCGGGTCAAGTAT
GAGTATTATCGGGAGAAGATTGGAGATGTGGACAATAGCCAGCAGCAGCTCTTAGTGCCCTATATCTTTGAATTTCCAGC
GGACGATATACTGCGGATCAAGCAGCGGATGGAGCTGTTAGAAGATGCTGGCATCTTTTTAGAGGAGTACGGAGCCAATC
AGTTTATCCTCCGTGAGCATCCCATTTGGTTCAAGGAAGAGGAGATTGAAGCAGGTATCTATGAGATGTGTGATATGCTT
CTCCTGACCAAGGAAGTTTCTATCAAGAAATATCGAGCAGAGCTGGCCATTATGATGAGCTGCAAACGCTCCATCAAGGC
CAATCACAGTCTGGATGACTACTCTGCGCGTGACTTGCTCTTTCAGCTGTCCCAGTGTGACAATCCTTACAACTGCCCAC
ACGGCCGACCGGTCTTAGTCAATTTTACCAAGTCGGATATGGAAAAAATGTTTCGCCGCATTCAGGAAAATCATACTAGC
CTGCGGGAGTTGGGGAAATACTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(449-591)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.658

100

0.779