Detailed information NTG0400209

Bioinformatically predicted

Overview

• Name: lytF
• Type: Regulator
• Locus tag: FOC72_RS10040
• Genome accession: NZ_CP054570
• Coordinates: 2074145..2076094 (+)
• Length: 649 a.a.
• NCBI ID: WP_002894339.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain FDAARGOS_770
• Function: cell lysis (predicted from homology) Cell lysis

Genomic Context

Location: 2069145..2081094

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC72_RS10025 (FOC72_10025)	-	2070677..2071768 (-)	1092	WP_002894344.1	RES domain-containing protein	-
FOC72_RS10030 (FOC72_10030)	-	2071772..2072716 (-)	945	WP_002894342.1	sce7725 family protein	-
FOC72_RS10035 (FOC72_10035)	-	2072729..2073556 (-)	828	WP_002894340.1	sce7726 family protein	-
FOC72_RS10040 (FOC72_10040)	lytF	2074145..2076094 (+)	1950	WP_002894339.1	murein hydrolase LytF	Regulator
FOC72_RS10045 (FOC72_10045)	purH	2076231..2077778 (-)	1548	WP_002894337.1	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	-
FOC72_RS10050 (FOC72_10050)	-	2077780..2078244 (-)	465	WP_002894335.1	GNAT family N-acetyltransferase	-
FOC72_RS10055 (FOC72_10055)	purN	2078289..2078840 (-)	552	WP_002894333.1	phosphoribosylglycinamide formyltransferase	-
FOC72_RS10060 (FOC72_10060)	purM	2078837..2079859 (-)	1023	WP_002894331.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 649 a.a.
• Molecular weight: 72062.51 Da
• Isoelectric Point: 6.7906

>NTDB_id=400209 FOC72_RS10040 WP_002894339.1 2074145..2076094(+) (lytF) [Streptococcus sanguinis strain FDAARGOS_770]
MKKYQKLFLLSGAVLGLFAGHSTVHATETPESEVKILGPTDRASNVDVTVNDRTASISYTRSQAQEPYLIAHAVWSEENG
QDDLKWYDTPQTPITDIDLSNHPGYGTFHVHTYIRIGERLVALNATTFHVDKPASKTNASVSGGTGRISFSRNKDQAHSK
IVHAVWSEEKGSDDLQWYDAGEESTEFNLSKHRGYGRYFVDTYENVNGKMIFLSGTTFHLENPKPIIETSFPQTGIMEIT
VKNVPDTMHRIVLPTWSDKKGQDDLQWYEASKNPDGSYSARVELRKHNYDTGAYNIHLYGQSYVQPESTGITGTTVEVDS
GKLPSDEEQKPLFTVENINPKQGTYTVKTTETSLSKPIQSVRVPIWSTSNQSNLKWYAATPNGDGSFSATFDIRNHQALS
GTYNNHVYVTYKDGSERSYAADAVSMSTDQIQAKVAVRKTEANRYEVTVTDAYGDGDIILPTWSEVNGQDDIKWYTANKV
GNGTYKFTVDTQNHKGSGLFNTHVYRRKAGQLIGLTGTSYHVEKSSVQSANIQPNYAAANATTYPVGQCTWGAKALAPWA
GNYWGNGGQWAASARRAGFRTGSTPEVGAIACWDDGGYGHVGVVTHVESNTRIQIQESNYLGKQYISNFRGWFDPTASYW
GRLTYIYPK

Nucleotide

• Length: 1950 bp

>NTDB_id=400209 FOC72_RS10040 WP_002894339.1 2074145..2076094(+) (lytF) [Streptococcus sanguinis strain FDAARGOS_770]
ATGAAGAAATATCAAAAACTGTTTTTATTATCCGGAGCTGTCCTAGGTCTCTTTGCAGGCCACTCAACAGTTCATGCGAC
CGAAACGCCTGAATCTGAAGTCAAAATTCTAGGTCCTACTGATCGTGCCAGCAATGTCGATGTGACTGTGAACGATCGTA
CAGCTTCTATTAGTTATACCCGTTCCCAAGCACAAGAACCTTATCTTATTGCTCATGCTGTTTGGTCTGAAGAAAACGGA
CAGGATGATTTGAAATGGTATGATACACCACAAACACCCATCACTGACATTGACTTAAGCAACCATCCAGGATATGGTAC
GTTTCATGTTCATACCTATATACGGATAGGAGAGCGCTTGGTAGCTCTAAATGCCACTACCTTTCATGTAGATAAACCAG
CTAGTAAAACGAATGCATCCGTCTCAGGAGGTACAGGGCGCATTAGCTTTTCCCGCAACAAAGACCAAGCTCACTCAAAG
ATTGTCCATGCTGTCTGGTCAGAAGAAAAAGGCAGCGACGACCTTCAGTGGTATGACGCAGGAGAAGAATCAACTGAATT
TAATCTTTCCAAACATCGTGGTTATGGACGATACTTCGTTGACACTTACGAAAATGTAAACGGAAAAATGATTTTCCTAT
CTGGTACTACGTTCCATCTTGAAAATCCGAAACCGATAATCGAAACCAGCTTCCCTCAGACCGGCATTATGGAAATTACT
GTCAAAAACGTACCCGATACCATGCATCGAATTGTTCTTCCAACTTGGTCTGATAAGAAAGGGCAAGATGATCTGCAATG
GTACGAAGCAAGCAAAAATCCAGATGGTAGCTACAGCGCTCGGGTGGAACTCAGAAAGCATAACTACGACACTGGGGCTT
ACAATATCCACCTTTACGGCCAAAGCTATGTTCAACCGGAATCAACTGGTATAACAGGAACGACAGTTGAAGTTGACAGT
GGAAAATTACCTTCGGACGAGGAACAGAAACCTCTTTTTACGGTGGAAAATATCAACCCCAAACAAGGGACCTACACCGT
GAAAACTACCGAAACTAGCTTATCTAAACCTATTCAATCTGTTCGGGTGCCAATTTGGAGCACTAGCAATCAGAGCAATC
TTAAATGGTATGCAGCCACTCCTAACGGAGATGGCTCCTTCAGCGCAACCTTTGATATCCGTAATCATCAGGCTTTGTCT
GGAACCTATAACAACCATGTATATGTCACCTATAAGGACGGCAGTGAGCGTAGCTACGCAGCAGATGCCGTCTCAATGTC
TACCGACCAAATTCAAGCCAAGGTTGCAGTCAGGAAAACTGAAGCTAATCGCTATGAGGTGACAGTGACAGACGCCTACG
GAGATGGCGATATTATTCTGCCAACTTGGTCAGAAGTCAATGGGCAAGATGATATCAAATGGTATACCGCCAATAAGGTC
GGCAATGGAACATACAAGTTTACCGTAGATACTCAGAATCACAAGGGAAGCGGTCTATTTAACACCCATGTCTATCGTAG
AAAAGCGGGACAGTTAATCGGCCTGACTGGAACTAGCTATCATGTTGAAAAATCAAGCGTTCAATCAGCTAATATTCAGC
CTAACTATGCCGCTGCTAATGCGACAACCTATCCTGTCGGTCAATGTACTTGGGGAGCCAAGGCTCTAGCTCCTTGGGCA
GGAAATTACTGGGGCAACGGCGGTCAATGGGCAGCTAGTGCCAGAAGAGCTGGATTCCGTACCGGCAGTACGCCTGAGGT
TGGCGCCATCGCCTGCTGGGATGACGGCGGCTACGGCCATGTCGGTGTCGTCACGCATGTCGAATCCAATACCCGCATCC
AGATCCAAGAGTCTAACTATCTCGGCAAGCAGTACATCAGCAACTTCCGTGGCTGGTTTGACCCAACTGCTTCCTACTGG
GGCCGCCTGACCTATATCTACCCTAAATAA

Domains

Predicted by InterProScan.

• CHAP domain (CHAP) (542-619)

• GBS Bsp-like repeat (GBS_Bsp-like) (233-307)

• GBS Bsp-like repeat (GBS_Bsp-like) (335-418)

• GBS Bsp-like repeat (GBS_Bsp-like) (70-116)

• GBS Bsp-like repeat (GBS_Bsp-like) (147-218)

• GBS Bsp-like repeat (GBS_Bsp-like) (438-514)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lytF	Streptococcus gordonii strain NCTC7865	44.571	80.894	0.361
lytF	Streptococcus gordonii str. Challis substr. CH1	44.571	80.894	0.361