Detailed information NTG0399660

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: HTZ88_RS02620
• Genome accession: NZ_CP054418
• Coordinates: 473303..475897 (+)
• Length: 864 a.a.
• NCBI ID: WP_014973956.1
• Uniprot ID: K0D978
• Organism: Leuconostoc carnosum strain 4010
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 468303..480897

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HTZ88_RS02585 (HTZ88_02570)	-	468433..468591 (-)	159	WP_014973950.1	hypothetical protein	-
HTZ88_RS02590 (HTZ88_02575)	-	468675..468950 (-)	276	WP_014973951.1	hypothetical protein	-
HTZ88_RS02595 (HTZ88_02580)	-	469036..469638 (-)	603	WP_014973952.1	DUF1643 domain-containing protein	-
HTZ88_RS02600	-	469703..469981 (-)	279	WP_014973953.1	ImmA/IrrE family metallo-endopeptidase	-
HTZ88_RS02605	-	469994..470134 (-)	141	WP_019040553.1	hypothetical protein	-
HTZ88_RS02610 (HTZ88_02590)	-	470247..470771 (-)	525	WP_014973954.1	NADPH-dependent FMN reductase	-
HTZ88_RS02615 (HTZ88_02595)	recG/mmsA	471227..473257 (+)	2031	WP_135198074.1	ATP-dependent DNA helicase RecG	Machinery gene
HTZ88_RS02620 (HTZ88_02600)	hexA	473303..475897 (+)	2595	WP_014973956.1	DNA mismatch repair protein MutS	Machinery gene
HTZ88_RS02625 (HTZ88_02605)	hexB	475991..477976 (+)	1986	WP_014973957.1	DNA mismatch repair endonuclease MutL	Machinery gene
HTZ88_RS02630 (HTZ88_02610)	-	478043..478558 (+)	516	WP_014973958.1	DUF1456 family protein	-
HTZ88_RS02635 (HTZ88_02615)	ndk	478612..479025 (+)	414	WP_014973959.1	nucleoside-diphosphate kinase	-
HTZ88_RS02640 (HTZ88_02620)	murB	479142..480020 (+)	879	WP_014973960.1	UDP-N-acetylmuramate dehydrogenase	-

Sequence

Protein

• Length: 864 a.a.
• Molecular weight: 96575.84 Da
• Isoelectric Point: 4.8491

>NTDB_id=399660 HTZ88_RS02620 WP_014973956.1 473303..475897(+) (hexA) [Leuconostoc carnosum strain 4010]
MAKIVDTPMMVQYHEIKAQYPDAFVFYRLGDFYELFEDDAILGAKILELTLTARNKNSENPVPMAGIPHHAAQNYIDILV
DQGHKVAIVEQMEDPAVAKGMVKRDVVQLITPGTKMLGGAGADKENNYLAALRPNGNDLAMAYIDLSTGELKATTIGNFN
DVIDELSSLEVKEVVLRKDDELTIKHQVANQLGERGLVISWQSDVTANATVSFLTQPLTSIAETETTAMLLNYIFDTQRR
NLDHIVPATSYERLTYLKFNQDTRSNLDLIENTRTKKRAGSLLGLIDETKTAMGGRLLKQWLLKPLREQQEIEKRLDLVQ
AFQNDFFTRGALQDDLKSVYDLERLAARAAMGTMNARELVQLKKSLLAIPSIKTTLSATEGVLYDAGDKLDSMVDLAGLI
DEAIVDDPPVSVREGNIINDGFDEKIDTYRRVLTDNQKWLAQLETDERKVTGISSLKVGYNKNFGYFIEVTKANINKLEP
DRYERRQTLTNAERFVTPELKAHERLIIEAQAKRTEREYELFVTIRERLKANISRIQKLARLVARLDVLASLADVADNRR
FVRPTFTSHNMIAISQGRHPVVEALLGSGEFVANDVMLDEDNAMQLITGPNMAGKSTYMRELALIVILAQMGSFVPAEQA
ELPIFDQIFTRIGANDDIAMGQSTFMVEMAEANLALREATAHSLILFDELGRGTATYDGMALAQAIIEFLDAHIHAKTLF
STHYHELTALADRHDSITNVHVGAVEDDNGELHFLHQIQEGPADKSYGIHVAALAGLPRELINNATTILSHLESDDVVTD
HQLVQQSVTSEKHDESQQVELFNVDAVDSETEKVLEHLDKLDILNMTPVDAMNALNDLKKLRKK

Nucleotide

• Length: 2595 bp

>NTDB_id=399660 HTZ88_RS02620 WP_014973956.1 473303..475897(+) (hexA) [Leuconostoc carnosum strain 4010]
ATGGCCAAAATAGTAGACACACCAATGATGGTGCAATATCATGAAATTAAGGCACAATACCCTGATGCATTTGTTTTTTA
TCGTTTAGGTGATTTTTATGAACTTTTTGAAGATGATGCGATATTAGGGGCTAAAATACTTGAATTAACACTGACAGCAC
GTAATAAAAATTCAGAAAACCCCGTGCCAATGGCGGGTATACCGCATCATGCTGCGCAAAATTATATTGATATTTTAGTA
GATCAAGGTCATAAAGTTGCTATTGTTGAGCAAATGGAAGATCCTGCCGTTGCTAAGGGTATGGTGAAGCGAGATGTTGT
TCAGCTGATTACGCCAGGCACAAAAATGCTTGGCGGTGCGGGTGCTGATAAAGAAAACAACTATCTAGCTGCTCTTAGAC
CAAACGGTAATGATTTGGCAATGGCTTATATTGATCTATCTACAGGCGAATTAAAAGCAACAACTATCGGTAACTTTAAT
GATGTGATTGATGAATTAAGTTCGTTGGAAGTTAAAGAAGTTGTGTTACGTAAAGATGACGAGCTTACCATAAAACATCA
AGTTGCTAATCAACTTGGGGAACGTGGTCTAGTAATTTCTTGGCAGTCAGATGTGACAGCAAATGCAACAGTTAGTTTTT
TGACACAACCCTTAACAAGCATTGCTGAAACTGAAACGACAGCAATGTTACTTAATTATATTTTTGATACGCAGCGCCGT
AATTTGGATCACATTGTGCCTGCTACGAGTTATGAGCGACTAACTTATTTGAAATTTAACCAAGACACACGTTCTAATTT
AGACTTAATTGAAAATACGCGTACGAAAAAACGTGCAGGTTCACTGCTAGGATTAATTGATGAGACGAAGACAGCTATGG
GTGGTCGGCTACTGAAACAGTGGCTACTAAAACCATTACGTGAGCAACAGGAGATTGAAAAGCGACTTGACTTGGTACAG
GCGTTTCAAAATGATTTTTTTACACGTGGTGCTTTGCAAGATGATTTGAAATCAGTATATGATTTGGAACGATTAGCAGC
TCGTGCGGCTATGGGTACGATGAATGCACGAGAACTTGTGCAACTCAAAAAATCATTATTAGCTATTCCAAGCATTAAAA
CCACTTTATCAGCAACAGAAGGAGTACTTTACGATGCTGGTGACAAGCTTGATAGCATGGTTGATTTGGCAGGGTTGATA
GATGAAGCTATTGTTGATGACCCACCGGTGAGTGTCCGTGAAGGTAATATTATTAACGACGGATTCGATGAAAAGATAGA
TACATATCGCAGAGTTTTGACTGACAATCAAAAATGGCTAGCCCAATTAGAAACTGATGAGCGTAAAGTTACCGGTATTA
GTTCATTGAAAGTCGGGTATAATAAAAATTTTGGTTATTTTATTGAAGTGACTAAAGCTAACATTAATAAATTAGAACCA
GATCGTTATGAGCGACGACAGACACTTACAAATGCAGAACGCTTTGTCACGCCAGAATTAAAAGCGCATGAACGTTTGAT
TATTGAGGCACAAGCTAAACGAACAGAAAGAGAATATGAATTATTTGTAACGATTCGTGAACGACTAAAGGCAAATATTA
GTCGTATTCAAAAGCTGGCAAGGTTAGTTGCGCGCTTGGATGTTTTAGCTTCACTAGCTGATGTCGCTGACAATCGCCGT
TTCGTACGTCCTACCTTTACTAGTCATAACATGATAGCCATATCTCAAGGAAGACATCCTGTGGTAGAAGCATTGCTCGG
TTCAGGTGAGTTTGTGGCAAATGATGTGATGTTAGATGAAGACAATGCCATGCAACTGATTACTGGTCCTAATATGGCTG
GAAAATCAACTTATATGCGTGAATTAGCCTTAATTGTTATCTTGGCACAAATGGGCAGTTTTGTACCAGCAGAACAAGCT
GAATTACCTATTTTTGATCAAATATTTACGCGAATTGGTGCTAATGATGATATTGCTATGGGACAGTCAACTTTTATGGT
TGAAATGGCAGAAGCTAACCTAGCTTTGCGAGAAGCAACAGCACATTCGCTTATTTTATTTGACGAATTAGGGCGTGGTA
CGGCAACTTATGACGGTATGGCACTGGCGCAAGCAATTATCGAATTTTTAGATGCGCATATTCATGCCAAAACACTGTTT
TCAACACATTATCATGAATTAACTGCATTAGCTGACCGGCATGATAGCATTACCAACGTTCATGTTGGTGCAGTAGAAGA
TGATAACGGGGAATTGCATTTTCTACATCAAATTCAAGAAGGACCAGCTGATAAATCTTATGGTATTCATGTTGCGGCAC
TGGCTGGCTTGCCACGCGAACTCATTAACAATGCTACGACCATTCTTTCTCATTTAGAAAGTGATGATGTCGTTACTGAT
CACCAGCTTGTCCAACAATCAGTGACGTCAGAAAAACATGACGAATCACAACAAGTTGAATTGTTCAATGTTGATGCTGT
TGATTCAGAGACAGAAAAAGTATTAGAACACTTAGATAAATTAGATATTTTAAACATGACACCTGTAGATGCCATGAATG
CACTAAATGACTTAAAAAAGTTAAGAAAAAAATAG

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (421-512)

• MutS domain I (MutS_I) (7-114)

• MutS domain III (MutS_III) (262-553)

• MutS domain II (MutS_II) (127-245)

• MutS domain V (MutS_V) (606-793)

3D structure

• AlphaFold DB: K0D978

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	47.368	98.958	0.469
mutS	Pseudomonas stutzeri strain ATCC 17587	38.844	100	0.389