Detailed information NTG0399435

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: GJE16_RS09340
• Genome accession: NZ_CP045931
• Coordinates: 1834106..1835116 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain AUSMDU00010538
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1829106..1840116

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJE16_RS09315 (GJE16_09315)	-	1829171..1830385 (-)	1215	WP_047475499.1	pyridoxal phosphate-dependent aminotransferase	-
GJE16_RS09320 (GJE16_09320)	-	1830541..1830835 (-)	295	Protein_1816	hypothetical protein	-
GJE16_RS09325 (GJE16_09325)	-	1830997..1831449 (+)	453	WP_000079148.1	universal stress protein	-
GJE16_RS09330 (GJE16_09330)	-	1831484..1832872 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
GJE16_RS09335 (GJE16_09335)	-	1832938..1833900 (+)	963	WP_001124777.1	asparaginase	-
GJE16_RS09340 (GJE16_09340)	ccpA	1834106..1835116 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
GJE16_RS09345 (GJE16_09345)	-	1835541..1836140 (-)	600	WP_000866719.1	response regulator transcription factor	-
GJE16_RS09350 (GJE16_09350)	-	1836142..1837239 (-)	1098	WP_000893546.1	sensor histidine kinase	-
GJE16_RS09355 (GJE16_09355)	-	1837239..1837976 (-)	738	WP_000832834.1	ABC transporter permease	-
GJE16_RS09360 (GJE16_09360)	-	1837978..1838862 (-)	885	WP_000219348.1	ABC transporter ATP-binding protein	-
GJE16_RS09365 (GJE16_09365)	-	1838849..1839043 (-)	195	WP_000820180.1	hypothetical protein	-
GJE16_RS09370 (GJE16_09370)	-	1839040..1839246 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=399435 GJE16_RS09340 WP_000990607.1 1834106..1835116(-) (ccpA) [Streptococcus pneumoniae strain AUSMDU00010538]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=399435 GJE16_RS09340 WP_000990607.1 1834106..1835116(-) (ccpA) [Streptococcus pneumoniae strain AUSMDU00010538]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568