Detailed information NTG0399434

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GJE16_RS09180
• Genome accession: NZ_CP045931
• Coordinates: 1805395..1806432 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain AUSMDU00010538
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1800395..1811432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GJE16_RS09155 (GJE16_09155)	-	1801134..1802465 (-)	1332	WP_000390039.1	hemolysin family protein	-
GJE16_RS09160 (GJE16_09160)	endA	1802756..1803580 (-)	825	WP_047474853.1	DNA-entry nuclease EndA	Machinery gene
GJE16_RS09165 (GJE16_09165)	-	1803619..1803807 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
GJE16_RS09170 (GJE16_09170)	murA	1803800..1805083 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
GJE16_RS09175 (GJE16_09175)	-	1805107..1805337 (-)	231	WP_000250392.1	DUF1146 family protein	-
GJE16_RS09180 (GJE16_09180)	sepM	1805395..1806432 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
GJE16_RS09185 (GJE16_09185)	coaD	1806416..1806904 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
GJE16_RS09190 (GJE16_09190)	rsmD	1806894..1807433 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
GJE16_RS09195 (GJE16_09195)	asnA	1807498..1808490 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
GJE16_RS09200 (GJE16_09200)	-	1808602..1809285 (-)	684	WP_001016913.1	Bax inhibitor-1 family protein	-
GJE16_RS09205 (GJE16_09205)	-	1809341..1810081 (-)	741	WP_088795428.1	TrmH family RNA methyltransferase	-
GJE16_RS09210 (GJE16_09210)	-	1810115..1810393 (+)	279	WP_001174613.1	acylphosphatase	-
GJE16_RS09215 (GJE16_09215)	yidC	1810471..1811397 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=399434 GJE16_RS09180 WP_000727276.1 1805395..1806432(-) (sepM) [Streptococcus pneumoniae strain AUSMDU00010538]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=399434 GJE16_RS09180 WP_000727276.1 1805395..1806432(-) (sepM) [Streptococcus pneumoniae strain AUSMDU00010538]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588