Detailed information NTG0399148

Bioinformatically predicted

Overview

• Name: comP
• Type: Regulator
• Locus tag: GII87_RS17165
• Genome accession: NZ_CP045922
• Coordinates: 3253117..3255426 (-)
• Length: 769 a.a.
• NCBI ID: WP_003242894.1
• Uniprot ID: Q99027
• Organism: Bacillus subtilis strain P8_B1
• Function: phosphorylation of ComA (predicted from homology) Competence regulation

Genomic Context

Location: 3248117..3260426

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GII87_RS17125 (GII87_17125)	mrpB	3248584..3249015 (+)	432	WP_003228819.1	Na(+)/H(+) antiporter subunit B	-
GII87_RS17130 (GII87_17130)	mrpC	3249015..3249356 (+)	342	WP_003220730.1	Na(+)/H(+) antiporter subunit C	-
GII87_RS17135 (GII87_17135)	mrpD	3249349..3250830 (+)	1482	WP_003244432.1	Na+/H+ antiporter subunit D	-
GII87_RS17140 (GII87_17140)	mrpE	3250836..3251312 (+)	477	WP_003244015.1	Na+/H+ antiporter subunit E	-
GII87_RS17145 (GII87_17145)	mrpF	3251312..3251596 (+)	285	WP_003228814.1	Na(+)/H(+) antiporter subunit F1	-
GII87_RS17150 (GII87_17150)	mnhG	3251580..3251954 (+)	375	WP_003244302.1	monovalent cation/H(+) antiporter subunit G	-
GII87_RS17155 (GII87_17155)	yuxO	3251993..3252373 (-)	381	WP_003228810.1	hotdog fold thioesterase	-
GII87_RS17160 (GII87_17160)	comA	3252392..3253036 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
GII87_RS17165 (GII87_17165)	comP	3253117..3255426 (-)	2310	WP_003242894.1	two-component system sensor histidine kinase ComP	Regulator
GII87_RS17170 (GII87_17170)	comX	3255441..3255608 (-)	168	WP_003242801.1	competence pheromone ComX	Regulator
GII87_RS17175 (GII87_17175)	comQ	3255596..3256495 (-)	900	WP_003243039.1	ComX modifying isoprenyl transferase ComQ	Regulator
GII87_RS17180 (GII87_17180)	degQ	3256680..3256820 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
GII87_RS17185 (GII87_17185)	-	3257042..3257167 (+)	126	WP_003228793.1	hypothetical protein	-
GII87_RS17190 (GII87_17190)	-	3257281..3257649 (+)	369	WP_003243784.1	hypothetical protein	-
GII87_RS17195 (GII87_17195)	pdeH	3257625..3258854 (-)	1230	WP_003243525.1	cyclic di-GMP phosphodiesterase	-

Sequence

Protein

• Length: 769 a.a.
• Molecular weight: 89308.77 Da
• Isoelectric Point: 8.2618

>NTDB_id=399148 GII87_RS17165 WP_003242894.1 3253117..3255426(-) (comP) [Bacillus subtilis strain P8_B1]
MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQFMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHL
KWGYLSHINSLDILRSGKKIHLKDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISI
AYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIFNLGIEFFQDYLQVDIDFLATLN
LVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLILTNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQ
FVANKMFDIEFILGRMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFRLKRFSEKF
NYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKVIFLDKHEVGPDWNFYQEEFENVTSEIGKII
EVNQGFLMKVGERGGSSYVLLCLSNINTPRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLM
FAIEEKQRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVISMTRETCHELRPQLLYD
LGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLYRIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDG
VGFDQEKNTEHSMSMGLSGIKERVRALDGRLRIETSEGKGFKADIEIEL

Nucleotide

• Length: 2310 bp

>NTDB_id=399148 GII87_RS17165 WP_003242894.1 3253117..3255426(-) (comP) [Bacillus subtilis strain P8_B1]
TTGAAGAACTTAATAAAAAAATTCACAATAGCTGTAATTGTTTTGAGTATCCTTTATATAAGCTATACAACTTATATCAG
TATGAATGGAATTATTATTGGGACTAAGATTCATAAAAATGATAAAAGTCAATTTATGATAGAAGAAATATCGGAATCTT
CATATGGACAATTTGTTGGTCTGAGACAGGGAGACATCATATTAAAAATTAATAAAGAAAAACCTTCAGACAAACATTTG
AAATGGGGATATTTGAGTCATATTAACAGTCTGGATATTTTGAGAAGTGGAAAAAAGATTCATCTCAAAGATTTTGATTT
AGTTACTCTAAATAGACCTTATAGTTTTTTTCTGTTCGTACTTCCTTTGTTTTTTTATTTTTTAAGCATAATATGTATTT
TTTATATACTTAAAGTAAATAAAAAAAGGAGATCATTTGCTGCCTATATTCTTATTCTATTGTTATTAGACATTTCGATA
GCATATATAAGTGCAGGCGGACCATTTAGAGGACATATAATCAATCGGTATATTAACTTGTTTACTTTTATATCTTCTCC
TATTCTTTATCTTCAATTTATACAAAGATACCTTGGAGAAATAGGTAAAACTTTTTTGAATAGAATTTCTTTTCTTTATA
TCATACCAATATTTAATCTTGGTATTGAGTTTTTTCAAGACTATTTACAAGTAGATATTGATTTTTTAGCAACTCTTAAT
TTGGTTTCTTTTGCAACTTTGACTCTATTTTCTTTTTCAGCGATATACTTACATCTTAATAAATATAAATATGCTGAGCA
TTCGTTTATTCTTAAATTACTAATTTTAACAAACACTCTTTCATTTGCGCCTTTTTTGATATTTTTTGTTCTTCCAATAA
TATTTACAGGTAATTATATTTTCCCGGCATTAGCTTCGGCGTCATTACTAGTACTAATTCCGTTCGGGTTAGTATACCAA
TTTGTAGCCAATAAGATGTTTGATATAGAGTTTATCTTAGGAAGAATGAGATACTATGCTCTACTTGCCATGATACCAAC
TCTTCTAATAGTTGGTGCATTAGTTCTGTTTGATGTAATGGACATCCAGATGAACCCTGTGCGTCAAACTGTATTTTTTT
TCGTTGTCATGTTCGCTGTCTTTTATTTTAAAGAGGTCATGGATTTTAAATTTCGGTTAAAACGTTTCTCCGAAAAATTC
AACTATCAGGACAGTATTTTTAAATATACTCAGCTAATGAGGGGTGTAACTTCTCTTCAACAAGTTTTTAAAGAACTGAA
AAATACTATACTGGATGTTTTGCTTGTAAGCAAAGCTTATACCTTTGAGGTTACTCCTGATCACAAAGTGATATTTTTAG
ATAAGCATGAAGTTGGACCGGACTGGAATTTTTATCAAGAGGAATTTGAAAACGTAACTTCAGAAATTGGGAAAATTATA
GAAGTCAATCAAGGCTTTCTTATGAAAGTTGGTGAACGAGGCGGTAGTTCTTATGTTCTGCTTTGTTTATCTAATATTAA
CACTCCCCGGCTAACACGTGATGAAATATCGTGGCTGAAAACACTGTCTTTTTATACAAGTGTGTCCATGGAAAATGTCC
TGCATATTGAGGAGCTCATGGAACATTTGAAGGACTTAAAACAAGAGGGAACCAACCCCATCTGGCTGAAAAAGCTAATG
TTTGCAATCGAAGAAAAACAGCGTTCAGGACTCGCCCGCGATCTCCACGATTCGGTTCTTCAGGATTTGATTTCCTTAAA
ACGCCAGTGTGAGCTGTTTTTGGGTGATTTCAAGAAGGATGATAATCCGTGCCGTGAAGAGGTGCAGGACAAGCTTGTAC
AGATGAATGAGCAGATGTCTGATGTGATTTCGATGACGAGGGAGACGTGTCATGAGCTGCGGCCGCAGCTTCTGTATGAT
CTTGGATTGGTGAAGGCGCTGTCGAAGCTGGTGGCGCAGCAGCAGGAGCGGGTTCCGTTTCATATCCGTTTAAATACCGG
GAGATTTACGGCTTCCCTTGATCTGGATTCGCAGCTGAATTTGTACCGGATCATTCAAGAGTTTCTGTCTAATGCGGTCA
AGCACTCTCAGGCGACGGATGTGCTGATTATGCTCATCAGTATTCAAAACAAAATCGTTCTTCATTATGAGGACGATGGC
GTTGGGTTTGATCAAGAAAAAAATACTGAGCATTCCATGAGCATGGGGCTTTCTGGCATTAAGGAGAGAGTCAGGGCTTT
AGATGGGCGCCTTCGGATTGAAACAAGTGAAGGAAAGGGCTTTAAGGCTGATATTGAAATCGAATTGTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (568-638)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (679-765)

3D structure

• AlphaFold DB: Q99027

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Bacillus subtilis subsp. subtilis str. 168	100	100	1