Detailed information NTG0398831

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB466_RS05755
• Genome accession: NZ_CP045866
• Coordinates: 1171968..1173011 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN007894
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1166968..1178011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB466_RS05725 (GIX97_05750)	-	1167389..1168645 (-)	1257	WP_001795108.1	aminopeptidase	-
AB466_RS05730 (GIX97_05755)	-	1168648..1168848 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB466_RS05735 (GIX97_05760)	-	1168995..1169459 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB466_RS05740 (GIX97_05765)	-	1169466..1169741 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB466_RS05745 (GIX97_05770)	-	1170019..1171236 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AB466_RS05750 (GIX97_05775)	vraR	1171349..1171978 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB466_RS05755 (GIX97_05780)	vraS	1171968..1173011 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB466_RS05760 (GIX97_05785)	liaF	1173008..1173709 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB466_RS05765 (GIX97_05790)	-	1173724..1174110 (-)	387	WP_001110179.1	hypothetical protein	-
AB466_RS05770 (GIX97_05795)	map	1174327..1175085 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB466_RS05775 (GIX97_05800)	-	1175616..1176602 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
AB466_RS05780 (GIX97_05805)	-	1177033..1177446 (-)	414	WP_001557448.1	hypothetical protein	-
AB466_RS05785 (GIX97_05810)	-	1177475..1177585 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=398831 AB466_RS05755 WP_001017131.1 1171968..1173011(-) (vraS) [Staphylococcus aureus strain CFSAN007894]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=398831 AB466_RS05755 WP_001017131.1 1171968..1173011(-) (vraS) [Staphylococcus aureus strain CFSAN007894]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1