Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   HR073_RS06625 Genome accession   NZ_CP054227
Coordinates   1434105..1436126 (+) Length   673 a.a.
NCBI ID   WP_000042533.1    Uniprot ID   Q324B3
Organism   Escherichia coli strain EcPF15     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1429105..1441126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HR073_RS06605 (HR073_06600) bioB 1429923..1430963 (+) 1041 WP_000951213.1 biotin synthase BioB -
  HR073_RS06610 (HR073_06605) bioF 1430960..1432114 (+) 1155 WP_000118805.1 8-amino-7-oxononanoate synthase -
  HR073_RS06615 (HR073_06610) bioC 1432101..1432856 (+) 756 WP_000246782.1 malonyl-ACP O-methyltransferase BioC -
  HR073_RS06620 (HR073_06615) bioD 1432849..1433526 (+) 678 WP_000044833.1 dethiobiotin synthase -
  HR073_RS06625 (HR073_06620) uvrB 1434105..1436126 (+) 2022 WP_000042533.1 excinuclease ABC subunit UvrB Machinery gene
  HR073_RS06630 (HR073_06625) yvcK 1436164..1437072 (-) 909 WP_001304790.1 uridine diphosphate-N-acetylglucosamine-binding protein YvcK -
  HR073_RS06635 (HR073_06630) moaA 1437469..1438458 (+) 990 WP_001295301.1 GTP 3',8-cyclase MoaA -
  HR073_RS06640 (HR073_06635) moaB 1438480..1438992 (+) 513 WP_000084639.1 molybdenum cofactor biosynthesis protein B -
  HR073_RS06645 (HR073_06640) moaC 1438995..1439480 (+) 486 WP_000080885.1 cyclic pyranopterin monophosphate synthase MoaC -
  HR073_RS06650 (HR073_06645) moaD 1439473..1439718 (+) 246 WP_000598612.1 molybdopterin synthase sulfur carrier subunit -
  HR073_RS06655 (HR073_06650) moaE 1439720..1440172 (+) 453 WP_001544393.1 molybdopterin synthase catalytic subunit MoaE -
  HR073_RS06660 (HR073_06655) ybhL 1440309..1441013 (+) 705 WP_000373624.1 Bax inhibitor-1/YccA family protein -

Sequence

Protein


Download         Length: 673 a.a.        Molecular weight: 76226.06 Da        Isoelectric Point: 4.8843

>NTDB_id=398313 HR073_RS06625 WP_000042533.1 1434105..1436126(+) (uvrB) [Escherichia coli strain EcPF15]
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS

Nucleotide


Download         Length: 2022 bp        

>NTDB_id=398313 HR073_RS06625 WP_000042533.1 1434105..1436126(+) (uvrB) [Escherichia coli strain EcPF15]
ATGAGTAAACCGTTCAAACTGAATTCCGCTTTTAAACCTTCTGGCGATCAGCCAGAGGCGATTCGACGTCTCGAAGAGGG
GCTGGAAGATGGCCTGGCGCACCAGACGTTACTTGGCGTGACTGGCTCCGGGAAAACCTTCACCATTGCCAATGTCATTG
CTGATCTTCAGCGCCCTACCATGGTACTTGCGCCCAACAAAACGCTGGCGGCCCAGTTGTATGGCGAAATGAAAGAGTTC
TTCCCGGAAAACGCGGTGGAATATTTCGTCTCCTACTACGACTACTATCAGCCGGAAGCCTATGTACCGAGTTCCGACAC
CTTCATTGAGAAAGATGCCTCGGTTAACGAACATATTGAACAGATGCGTTTGTCCGCCACCAAAGCGATGCTGGAGCGGC
GTGATGTGGTTGTGGTGGCGTCTGTTTCCGCGATTTATGGTCTGGGCGATCCTGATTTATATCTCAAGATGATGCTCCAT
CTCACGGTCGGCATGATTATCGATCAGCGCGCGATCCTGCGCCGACTGGCGGAGCTGCAATACGCTCGTAATGATCAGGC
ATTCCAGCGTGGTACTTTCCGCGTTCGTGGTGAGGTGATTGATATCTTCCCAGCAGAATCGGATGACATTGCACTTCGCG
TGGAGCTGTTTGACGAGGAAGTGGAACGATTGTCGTTATTTGACCCGCTCACCGGGCAGATTGTTTCCACTATTCCACGT
TTTACCATCTACCCGAAAACGCACTACGTCACGCCGCGCGAGCGCATCGTACAGGCGATGGAAGAGATCAAAGAAGAACT
GGCCGCCAGACGCAAAGTGCTGTTGGAGAACAACAAGTTGCTTGAAGAGCAGCGGCTGACCCAGCGTACCCAGTTTGATC
TGGAGATGATGAACGAGCTGGGCTACTGTTCCGGGATTGAGAACTACTCGCGCTTCCTCTCCGGTCGTGGACCGGGTGAG
CCACCGCCGACGCTGTTTGATTACCTGCCTGCCGATGGGCTGCTGGTGGTCGATGAATCACACGTCACCATTCCGCAAAT
TGGCGGCATGTATCGCGGTGACCGGGCGCGTAAAGAGACGCTGGTGGAGTACGGCTTCCGCCTGCCATCAGCGCTGGATA
ACCGTCCGCTGAAATTTGAAGAGTTCGAAGCATTAGCGCCGCAAACCATCTATGTTTCGGCGACGCCGGGTAATTACGAG
CTGGAAAAATCGGGCGGCGATGTGGTGGATCAGGTGGTGCGTCCAACCGGATTGCTTGATCCGATTATCGAAGTGCGGCC
AGTGGCGACACAGGTCGATGATCTTCTATCGGAGATTCGTCAGCGAGCGGCAATTAACGAACGCGTACTGGTTACAACTC
TGACCAAGCGAATGGCGGAAGATCTCACGGAATATCTCGAAGAACACGGCGAGCGCGTGCGTTATCTTCACTCAGATATC
GACACCGTCGAACGTATGGAGATTATCCGCGACTTGCGTCTGGGCGAGTTCGACGTGCTGGTGGGGATCAACTTACTGCG
CGAAGGTCTGGATATGCCGGAGGTTTCGCTGGTGGCGATCCTCGACGCCGACAAAGAAGGCTTCCTGCGTTCTGAACGTT
CGTTGATCCAGACTATTGGTCGTGCGGCGCGTAACGTTAACGGTAAAGCGATTCTCTACGGCGATAAGATCACCCCGTCA
ATGGCGAAAGCGATTGGCGAAACCGAACGTCGCCGCGAGAAACAGCAGAAGTACAACGAGGAACACGGCATTACGCCGCA
AGGCTTGAACAAGAAAGTGGTCGATATTCTGGCGTTGGGGCAGAACATTGCCAAAACCAAAGCGAAGGGCAGAGGAAAAT
CGCGACCGATTGTTGAGCCGGATAATGTGCCGATGGATATGTCGCCTAAAGCGTTGCAGCAGAAGATCCATGAACTGGAA
GGGTTGATGATGCAACACGCGCAGAATCTGGAGTTCGAAGAAGCGGCGCAAATTCGTGACCAGTTGCATCAGTTGCGTGA
GCTGTTTATTGCCGCGTCGTGA

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(159-249)

UvrB/uvrC motif (UVR)

(634-667)

Ultra-violet resistance protein B (UvrB)

(552-593)

Type III restriction enzyme, res subunit (ResIII)

(13-92)

Helicase conserved C-terminal domain (Helicase_C)

(436-544)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q324B3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae TIGR4

56.372

99.108

0.559
  uvrB Streptococcus pneumoniae R6

56.222

99.108

0.557
  uvrB Streptococcus pneumoniae D39

56.222

99.108

0.557

Multiple sequence alignment