Detailed information    

insolico Bioinformatically predicted

Overview


Name   comW   Type   Regulator
Locus tag   INV104_RS00135 Genome accession   NC_017591
Coordinates   22353..22589 (+) Length   78 a.a.
NCBI ID   WP_000939548.1    Uniprot ID   -
Organism   Streptococcus pneumoniae INV104     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context


Location: 17353..27589
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INV104_RS11420 (INV104_00140) - 20409..21255 (+) 847 Protein_14 IS630 family transposase -
  INV104_RS11425 (INV104_00150) - 21290..22087 (-) 798 Protein_15 transposase -
  INV104_RS00135 (INV104_00160) comW 22353..22589 (+) 237 WP_000939548.1 sigma(X)-activator ComW Regulator
  INV104_RS00140 (INV104_00170) - 22820..24106 (+) 1287 WP_001818679.1 adenylosuccinate synthase -
  INV104_RS00145 (INV104_00180) tadA 24307..24774 (+) 468 WP_000291870.1 tRNA adenosine(34) deaminase TadA -
  INV104_RS00150 (INV104_00190) - 24961..25404 (+) 444 WP_000701992.1 dUTP diphosphatase -
  INV104_RS00155 (INV104_00200) - 25406..25921 (+) 516 WP_000691235.1 histidine phosphatase family protein -
  INV104_RS00160 (INV104_00210) radA 25935..27296 (+) 1362 WP_078157384.1 DNA repair protein RadA Machinery gene

Sequence


Protein


Download         Length: 78 a.a.        Molecular weight: 9716.17 Da        Isoelectric Point: 6.7051

>NTDB_id=39765 INV104_RS00135 WP_000939548.1 22353..22589(+) (comW) [Streptococcus pneumoniae INV104]
MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=39765 INV104_RS00135 WP_000939548.1 22353..22589(+) (comW) [Streptococcus pneumoniae INV104]
ATGTTACAAAAAATTTATGAGCAGATGACTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

97.436

100

0.974

  comW Streptococcus pneumoniae D39

97.436

100

0.974

  comW Streptococcus pneumoniae R6

97.436

100

0.974

  comW Streptococcus pneumoniae TIGR4

97.436

100

0.974

  comW Streptococcus mitis SK321

76.923

100

0.769

  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756


Multiple sequence alignment