Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HRS05_RS14575 Genome accession   NZ_CP054161
Coordinates   3063873..3064529 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain STO_Bone2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3058873..3069529
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRS05_RS14545 (HRS05_14475) dcyD 3059753..3060739 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  HRS05_RS14550 (HRS05_14480) tcyL 3060754..3061422 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  HRS05_RS14555 (HRS05_14485) tcyN 3061419..3062171 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HRS05_RS14560 (HRS05_14490) sdiA 3062401..3063123 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  HRS05_RS14565 (HRS05_14495) yecF 3063190..3063414 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  HRS05_RS14570 (HRS05_14500) yecU 3063401..3063577 (-) 177 WP_000590347.1 protein YecU -
  HRS05_RS14575 (HRS05_14505) letA 3063873..3064529 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HRS05_RS14580 (HRS05_14510) uvrC 3064526..3066358 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HRS05_RS14585 (HRS05_14515) pgsA 3066415..3066963 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HRS05_RS14605 (HRS05_14535) yecA 3067613..3068278 (+) 666 WP_000847881.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=397643 HRS05_RS14575 WP_000611328.1 3063873..3064529(+) (letA) [Escherichia coli strain STO_Bone2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=397643 HRS05_RS14575 WP_000611328.1 3063873..3064529(+) (letA) [Escherichia coli strain STO_Bone2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment