Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HQ617_RS06235 Genome accession   NZ_CP054055
Coordinates   1207474..1209255 (-) Length   593 a.a.
NCBI ID   WP_001003954.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain GBS47     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1202474..1214255
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HQ617_RS06215 (HQ617_06180) - 1202745..1203329 (-) 585 WP_000130600.1 uracil-DNA glycosylase family protein -
  HQ617_RS06220 (HQ617_06185) pepV 1203426..1204832 (-) 1407 WP_000150958.1 dipeptidase PepV -
  HQ617_RS06225 (HQ617_06190) - 1204879..1205481 (-) 603 WP_000670189.1 nitroreductase family protein -
  HQ617_RS06230 (HQ617_06195) - 1205651..1207432 (+) 1782 WP_235065581.1 glycerophosphodiester phosphodiesterase -
  HQ617_RS06235 (HQ617_06200) uvrC 1207474..1209255 (-) 1782 WP_001003954.1 excinuclease ABC subunit UvrC Machinery gene
  HQ617_RS06240 (HQ617_06205) - 1209414..1210181 (+) 768 WP_000567585.1 epoxyqueuosine reductase QueH -
  HQ617_RS06245 (HQ617_06210) - 1210240..1211580 (-) 1341 WP_000285046.1 MATE family efflux transporter -
  HQ617_RS06250 (HQ617_06215) - 1211680..1212096 (-) 417 WP_000245056.1 VOC family protein -
  HQ617_RS06255 (HQ617_06220) - 1212100..1212597 (-) 498 WP_000582587.1 hypothetical protein -
  HQ617_RS06260 (HQ617_06225) - 1212819..1213415 (+) 597 WP_000162275.1 Ltp family lipoprotein -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68319.81 Da        Isoelectric Point: 9.5330

>NTDB_id=397434 HQ617_RS06235 WP_001003954.1 1207474..1209255(-) (uvrC) [Streptococcus agalactiae strain GBS47]
MNELIKHKLELLPDSPGCYLHKDKNGTIIYVGKAKNLKNRVKSYFHGSHNTKTELLVSEIEDFEYIVTTSNTEALLLEIN
LIQENMPKYNIRLKDDKSYPYIKITNERYPRLMITRQVKKSDGTYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCNAHTVCQTNKAYWDSLREDVKQFLNGKDNKIVNGLTEKMKSAAMTMEFERAAEYRDLIEAISLLRTKQRVIHQ
DMKDRDVFGYFVDKGWMCVQVFFVRNGKLIQRDVNMFPYYNEPEEDFLTYIGQFYQDTKHFLPKEVFIPQDIDAKSVETI
VGCKIVKPQRGEKKQLVNLAIKNARVSLQQKFDLLEKDIRKTHGAIENLGNLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVNGKPSKKDYRKFKIKTVIGPDDYASMREVIHRRYSRVLKDGLTPPDLIVIDGGQGQVNIARDVIENQLGLAIPIAGLQ
KNDKHQTHELLFGDPLEVVELPRNSEEFFLLHRIQDEVHRFAITFHRQLRSKNSFSSKLDGITGLGPKRKQLLMKHFKSL
SSIQKADIEDIIMCGIPRNVAESLRDSLNDPPK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=397434 HQ617_RS06235 WP_001003954.1 1207474..1209255(-) (uvrC) [Streptococcus agalactiae strain GBS47]
ATGAATGAACTGATTAAACATAAGCTAGAATTGTTACCAGACAGTCCTGGTTGTTACCTTCATAAAGATAAGAATGGGAC
AATTATTTATGTAGGTAAGGCTAAAAATCTTAAGAATCGTGTGAAAAGTTATTTTCATGGGAGTCATAATACTAAGACAG
AACTTTTGGTCTCTGAGATTGAAGACTTTGAATACATTGTGACAACATCTAATACCGAAGCTCTATTATTGGAAATTAAT
TTAATCCAAGAAAATATGCCGAAGTATAATATTCGATTGAAAGATGATAAGTCTTACCCATATATCAAAATAACAAATGA
ACGTTATCCTCGTCTTATGATTACACGTCAAGTAAAAAAATCAGATGGCACTTATTTTGGACCTTATCCGGATTCTGGGG
CAGCAACTGAGATTAAGCGGTTACTAGATAGGCTCTTTCCTTTTAAGAAATGTACTAATCCAGCAAATAAAGTATGCTTT
TATTATCATTTAGGGCAATGCAATGCACATACAGTTTGTCAAACTAATAAAGCTTATTGGGATAGTCTGAGAGAAGATGT
AAAACAGTTTCTTAATGGTAAAGATAATAAAATTGTTAACGGATTAACTGAAAAAATGAAGAGCGCTGCTATGACTATGG
AATTTGAGCGTGCGGCTGAATATCGAGATTTGATCGAAGCAATTAGTTTGTTGCGTACTAAGCAGCGTGTTATTCATCAA
GATATGAAGGATAGAGATGTTTTTGGTTATTTCGTTGATAAGGGTTGGATGTGTGTACAGGTCTTTTTTGTTCGAAATGG
AAAATTGATTCAGCGTGACGTGAATATGTTTCCTTATTATAATGAACCAGAGGAAGATTTTCTAACTTACATAGGGCAAT
TTTATCAAGATACAAAACATTTTCTACCCAAAGAAGTCTTTATTCCACAGGATATTGATGCTAAGTCGGTTGAAACAATT
GTAGGCTGTAAGATTGTTAAACCACAACGTGGTGAAAAGAAACAGTTAGTAAATCTGGCAATAAAAAATGCTCGTGTCAG
TTTACAACAGAAGTTTGACTTACTGGAAAAAGATATTCGTAAAACTCATGGGGCAATTGAAAATTTAGGTAATCTTCTTA
ATATCCCTAAACCAGTACGCATAGAAGCATTTGATAATTCCAATATTCAAGGGACAAGTCCAGTAGCTGCTATGGTGGTA
TTTGTGAATGGAAAGCCAAGTAAAAAAGACTATCGAAAGTTTAAAATTAAGACTGTTATCGGACCAGATGATTATGCTAG
TATGAGAGAAGTCATTCATCGGCGTTATAGTAGGGTTTTAAAAGATGGCTTGACACCTCCGGACTTGATTGTAATTGATG
GTGGTCAGGGGCAAGTAAATATAGCGCGTGATGTTATTGAGAACCAATTAGGTTTAGCCATACCTATTGCAGGTTTGCAA
AAGAATGATAAACACCAAACACATGAATTACTTTTTGGAGATCCTTTAGAAGTAGTAGAACTACCGCGTAATTCAGAAGA
ATTTTTCTTACTTCACCGTATTCAAGATGAGGTACATCGTTTTGCTATTACTTTTCATCGTCAATTACGCTCCAAAAATT
CCTTTTCTTCAAAATTAGATGGTATCACTGGGTTGGGACCCAAACGTAAACAATTGCTAATGAAACATTTTAAAAGCTTA
TCTAGTATCCAAAAAGCTGATATTGAGGACATTATTATGTGTGGTATTCCTAGGAATGTAGCAGAAAGTCTCCGAGATTC
TCTTAATGATCCTCCTAAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(197-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.57

99.325

0.761
  uvrC Streptococcus pneumoniae R6

76.231

99.325

0.757
  uvrC Streptococcus pneumoniae D39

76.231

99.325

0.757

Multiple sequence alignment