Detailed information NTG0397216

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: HRD51_RS23360
• Genome accession: NZ_CP054019
• Coordinates: 5209892..5211013 (-)
• Length: 373 a.a.
• NCBI ID: WP_205366134.1
• Uniprot ID: -
• Organism: Streptomyces sp. A1-5
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 5204892..5216013

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HRD51_RS23340 (HRD51_23005)	-	5205783..5206742 (-)	960	WP_235094014.1	A/G-specific adenine glycosylase	-
HRD51_RS23345 (HRD51_23010)	-	5206923..5207582 (+)	660	WP_235094015.1	pyridoxamine 5'-phosphate oxidase family protein	-
HRD51_RS23350 (HRD51_23015)	-	5207894..5208721 (+)	828	WP_235094016.1	hypothetical protein	-
HRD51_RS23355 (HRD51_23020)	-	5208850..5209848 (+)	999	WP_235094017.1	NAD-dependent epimerase/dehydratase family protein	-
HRD51_RS23360 (HRD51_23025)	disA	5209892..5211013 (-)	1122	WP_205366134.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
HRD51_RS23365 (HRD51_23030)	radA/sms	5211146..5212558 (-)	1413	WP_235094018.1	DNA repair protein RadA	Machinery gene
HRD51_RS23370 (HRD51_23035)	-	5212786..5214543 (+)	1758	WP_235094019.1	sigma-70 family RNA polymerase sigma factor	-
HRD51_RS23375 (HRD51_23040)	-	5214568..5215434 (-)	867	WP_039634085.1	hypothetical protein	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 40257.09 Da
• Isoelectric Point: 4.9340

>NTDB_id=397216 HRD51_RS23360 WP_205366134.1 5209892..5211013(-) (disA) [Streptomyces sp. A1-5]
MAANDRASSPGRSAGTGTESLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGFDKTVESMCTGGFVLDVEFTATRLRE
LCKLDGALVLDKDITKILRAGVQLVPDASIPTEETGTRHRTAQRVSIQTNFPVVSVSQSMRLIALYVDGERRVLEESAAI
LSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLTLQLEELIAG
VEPERELVARDYVPEPTAKRSRTVAEALAELDALTHPELLELPIVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGAV
IDRLVDHFGGLQKLLAASVDDLQAVEGVGETRARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1122 bp

>NTDB_id=397216 HRD51_RS23360 WP_205366134.1 5209892..5211013(-) (disA) [Streptomyces sp. A1-5]
GTGGCAGCGAACGACCGGGCGTCGTCTCCCGGCAGGTCCGCAGGGACCGGCACCGAGAGCCTGATGCGCGCCTCGCTGAG
CGCCGTCGCGCCCGGTACGGCCCTGCGGGACGGCCTGGAACGCATCCTCCGCGGCAACACGGGCGGCCTGATCGTCCTCG
GCTTCGACAAGACCGTCGAGTCCATGTGCACCGGCGGCTTCGTCCTCGACGTCGAGTTCACCGCGACCCGCCTGCGCGAG
CTGTGCAAGCTCGACGGCGCGCTGGTCCTCGACAAGGACATCACCAAGATCCTCCGGGCCGGGGTCCAGCTGGTGCCGGA
CGCCTCGATCCCCACCGAGGAGACCGGCACCCGCCACCGCACCGCCCAGCGGGTCTCCATCCAGACCAACTTCCCGGTGG
TCTCGGTCAGCCAGTCCATGCGCCTGATCGCGCTCTACGTGGACGGCGAGCGCCGCGTCCTGGAGGAGTCCGCCGCGATC
CTCTCCCGCGCCAACCAGGCGCTGGCCACCCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTCGCCGGCACCCTCTCCGC
CCTGGAGATCGAGGACCTGGTCACGGTCCGCGACGTCTCCGCGGTCGCCCAGCGCCTGGAGATGGTCCGCCGGATCGCCA
CCGAGATCGCCGAGTACGTCGTCGAACTGGGCACCGACGGCCGCCTGCTGACCCTCCAGCTCGAAGAGCTGATCGCCGGG
GTGGAGCCGGAGCGCGAGCTGGTCGCCCGGGACTACGTCCCCGAGCCCACCGCCAAGCGCTCCCGCACGGTCGCCGAGGC
ACTGGCCGAGCTGGACGCCCTCACCCACCCCGAGCTGCTCGAACTCCCCATAGTGGCCCGCGCGTTGGGCTACAGCGGCT
CGCCCGAGACGCTGGACTCGGCGGTCTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTCCCCCGCCTCCCCGGCGCCGTC
ATCGACCGCCTGGTCGACCACTTCGGCGGCCTCCAGAAGCTCCTCGCCGCCAGCGTCGACGACCTCCAGGCGGTCGAGGG
TGTCGGCGAGACCCGCGCCCGCTCGGTCCGCGAGGGCCTCTCCCGCCTGGCGGAGTCGTCGATCCTGGAGCGGTACGTCT
AG

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller linker region (DisA-linker) (154-296)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (37-150)

• Helix-hairpin-helix motif (HHH) (331-358)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	44.818	95.71	0.429