Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FOC63_RS06500 Genome accession   NZ_CP054015
Coordinates   1277331..1277975 (+) Length   214 a.a.
NCBI ID   WP_009853571.1    Uniprot ID   A0A060RG88
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1272331..1282975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS06480 (FOC63_06480) - 1272905..1273642 (+) 738 WP_009853567.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  FOC63_RS06485 (FOC63_06485) pknB 1273642..1275519 (+) 1878 WP_009853568.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  FOC63_RS06490 (FOC63_06490) liaF 1275630..1276325 (+) 696 WP_009853569.1 cell wall-active antibiotics response protein LiaF -
  FOC63_RS06495 (FOC63_06495) - 1276322..1277347 (+) 1026 WP_009853570.1 sensor histidine kinase -
  FOC63_RS06500 (FOC63_06500) vraR 1277331..1277975 (+) 645 WP_009853571.1 response regulator transcription factor Regulator
  FOC63_RS06505 (FOC63_06505) - 1278094..1279494 (+) 1401 WP_009853572.1 Cof-type HAD-IIB family hydrolase -
  FOC63_RS06510 (FOC63_06510) - 1279494..1279850 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  FOC63_RS06515 (FOC63_06515) cysK 1279964..1280893 (-) 930 WP_009853573.1 cysteine synthase A -
  FOC63_RS06520 (FOC63_06520) - 1280997..1281623 (-) 627 WP_009853574.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23939.71 Da        Isoelectric Point: 4.6633

>NTDB_id=397138 FOC63_RS06500 WP_009853571.1 1277331..1277975(+) (vraR) [Streptococcus gallolyticus strain FDAARGOS_755]
MTQKIKVILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=397138 FOC63_RS06500 WP_009853571.1 1277331..1277975(+) (vraR) [Streptococcus gallolyticus strain FDAARGOS_755]
ATGACCCAGAAAATTAAAGTTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGTTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTTGGCGAAGCTGGAAATGGTTTAGATGGTATCAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGTGGTGTCGAAGCAACATTAAAGCTTCTAGAAGAATGGAAGGAAGCTAAA
ATTCTTGTTTTAACATCTTACCTTGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGCGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAATCAAACTATTGCTGATGAGCTATTTATCTCACTAAAAACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTTGATGACCGTACACAAGCAGTCGTTTATGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RG88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.262

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393