Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   FOC63_RS04610 Genome accession   NZ_CP054015
Coordinates   909416..909709 (+) Length   97 a.a.
NCBI ID   WP_012961329.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain FDAARGOS_755     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 904416..914709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC63_RS04585 (FOC63_04585) - 906407..906775 (+) 369 WP_009853228.1 DUF1033 family protein -
  FOC63_RS04590 (FOC63_04590) comGA 906846..907787 (+) 942 WP_009853229.1 competence type IV pilus ATPase ComGA Machinery gene
  FOC63_RS04595 (FOC63_04595) comGB 907669..908754 (+) 1086 WP_012961328.1 competence type IV pilus assembly protein ComGB Machinery gene
  FOC63_RS04600 (FOC63_04600) comGC 908754..909047 (+) 294 WP_009853231.1 competence type IV pilus major pilin ComGC Machinery gene
  FOC63_RS04605 (FOC63_04605) comGD 909031..909462 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  FOC63_RS04610 (FOC63_04610) comGE 909416..909709 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE Machinery gene
  FOC63_RS04615 (FOC63_04615) comGF 909663..910130 (+) 468 WP_012961330.1 competence type IV pilus minor pilin ComGF Machinery gene
  FOC63_RS04620 (FOC63_04620) comGG 910102..910416 (+) 315 WP_009853235.1 competence type IV pilus minor pilin ComGG Machinery gene
  FOC63_RS04625 (FOC63_04625) comGH 910489..911445 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  FOC63_RS04630 (FOC63_04630) - 911498..912697 (+) 1200 WP_009853237.1 acetate kinase -
  FOC63_RS04635 (FOC63_04635) - 912859..913059 (+) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  FOC63_RS04640 (FOC63_04640) - 913069..913278 (+) 210 WP_009853239.1 hypothetical protein -
  FOC63_RS04645 (FOC63_04645) - 913291..913743 (+) 453 WP_009853240.1 hypothetical protein -
  FOC63_RS04650 (FOC63_04650) - 913755..914393 (+) 639 WP_009853241.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10952.89 Da        Isoelectric Point: 8.4757

>NTDB_id=397116 FOC63_RS04610 WP_012961329.1 909416..909709(+) (comGE) [Streptococcus gallolyticus strain FDAARGOS_755]
MVNIKRQKLKAYILLESLIALGLLAMITSIVLGEIDKNRQSMQESLRQQEALNVATMAVQTGQNHLKMNGVEVEIIKKDG
EVYVYEGKTEILHVKKD

Nucleotide


Download         Length: 294 bp        

>NTDB_id=397116 FOC63_RS04610 WP_012961329.1 909416..909709(+) (comGE) [Streptococcus gallolyticus strain FDAARGOS_755]
GTGGTAAATATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAAAGCTTGATAGCACTAGGATTGTTAGCGATGAT
TACGAGTATTGTTTTAGGGGAAATTGATAAAAATAGGCAGTCTATGCAAGAAAGTTTACGGCAGCAGGAAGCTCTTAATG
TGGCAACAATGGCTGTGCAAACAGGACAAAATCATTTGAAGATGAATGGTGTTGAGGTTGAGATTATCAAAAAAGATGGA
GAGGTCTATGTTTATGAGGGGAAAACGGAAATATTACACGTTAAAAAAGACTAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

47.917

98.969

0.474
  comGE Streptococcus mutans UA159

47.917

98.969

0.474
  comGE/cglE Streptococcus mitis SK321

42.553

96.907

0.412
  comGE/cglE Streptococcus pneumoniae Rx1

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae D39

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae R6

41.489

96.907

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

41.489

96.907

0.402
  comGE/cglE Streptococcus mitis NCTC 12261

41.489

96.907

0.402