Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FOC73_RS05740 Genome accession   NZ_CP053998
Coordinates   1183113..1185056 (+) Length   647 a.a.
NCBI ID   WP_004181935.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1178113..1190056
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS05710 (FOC73_05710) argR 1178318..1178746 (+) 429 WP_170314548.1 arginine repressor -
  FOC73_RS05715 (FOC73_05715) - 1178746..1179105 (+) 360 WP_002889586.1 YlbF family regulator -
  FOC73_RS05720 (FOC73_05720) hexA 1179098..1181656 (+) 2559 WP_004181956.1 DNA mismatch repair protein MutS Machinery gene
  FOC73_RS05725 (FOC73_05725) - 1181690..1182145 (-) 456 WP_004181953.1 DUF3021 domain-containing protein -
  FOC73_RS05730 (FOC73_05730) - 1182142..1182579 (-) 438 WP_004181975.1 LytTR family DNA-binding domain-containing protein -
  FOC73_RS05735 (FOC73_05735) - 1182758..1183063 (+) 306 WP_004181965.1 hypothetical protein -
  FOC73_RS05740 (FOC73_05740) hexB 1183113..1185056 (+) 1944 WP_004181935.1 DNA mismatch repair endonuclease MutL Machinery gene
  FOC73_RS05745 (FOC73_05745) - 1185187..1185408 (+) 222 WP_002886321.1 hypothetical protein -
  FOC73_RS05750 (FOC73_05750) ruvA 1185565..1186155 (+) 591 WP_004181981.1 Holliday junction branch migration protein RuvA Machinery gene
  FOC73_RS05755 (FOC73_05755) - 1186164..1186718 (+) 555 WP_004181971.1 DNA-3-methyladenine glycosylase I -
  FOC73_RS05760 (FOC73_05760) cinA 1186815..1188083 (+) 1269 WP_004181942.1 competence/damage-inducible protein A Machinery gene
  FOC73_RS05765 (FOC73_05765) recA 1188119..1189258 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  FOC73_RS05770 (FOC73_05770) spx 1189427..1189825 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72526.72 Da        Isoelectric Point: 5.3747

>NTDB_id=396916 FOC73_RS05740 WP_004181935.1 1183113..1185056(+) (hexB) [Streptococcus salivarius strain FDAARGOS_771]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISYLTIVTAAAGEAYGTKLVAKGGKIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQISGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRGATKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLISESESPVSSVENKP
QPSVKQAQRSVDEGDSEHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMSLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=396916 FOC73_RS05740 WP_004181935.1 1183113..1185056(+) (hexB) [Streptococcus salivarius strain FDAARGOS_771]
ATGCCAAAAATCATCGAATTACCTGAGGTGTTAGCCAACCAGATTGCTGCTGGTGAGGTCGTAGAGCGCCCAGCCAGTGT
TGTTAAAGAGTTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGATAATGGCGAAGGAATGGCTCAAGCTGATGTGGCCATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCCTCAATAGCTTCTATCAG
CTACCTAACTATTGTGACAGCAGCGGCTGGAGAAGCCTATGGGACTAAACTGGTTGCTAAAGGTGGAAAAATTGAGAGTC
AGGATCCTATTTCAACACCGGTTGGAACAAAGATTACCGTTGAAAATCTATTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTAAGTCTAGCTCATCCCGAGGTTGCCTT
TACCTTGCTTAATGATGGTCGTCAGTTGACACAGATATCAGGTACTGGAGACCTCCGTCAGGCTATTGCCGGGATTTATG
GTTTAACAACGGCTAAAAAAATGGTGGAAATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGATATGTTAGTCTCCCT
GAGTTGACCCGTGCGAATCGTAACTACATCACGATTCTCATTAACGGACGTTATATTAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTTCCTATTGCGGTTATTGATATTCAGATTGATCCTTATT
TGGCTGATGTCAATGTTCACCCAACCAAGCAGGAAGTACGTATTTCTAAAGAAAAAGAGCTTATGGCCCTTATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCGAGTACTAGAGGTGC
AACTAAGCCAGTGCAAACGAGTTTACCACTCAAACAGACCAATCTTTACTATGATAGCAGTCGTAATGATTTTTTTGTCA
AACCAGAGACCGTCCAAGAGGATATCAAACCTCTTATATCGGAGTCAGAGTCTCCAGTTTCATCGGTAGAAAATAAACCG
CAACCTTCTGTTAAACAGGCACAACGTTCAGTAGATGAAGGTGATAGCGAACACGAAAAACTTGATTATAAAAACAAGTC
GAAAATGAAGCGCATGCTTGAAACTCTGGACAATGAGGAAACATCAACCTTCCCTGAATTAGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATTGGTGAGGTTGACAGCAGTTTACAGCAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCAGACTACATTAGTTTACAAGAAAAAATGTCCCTTCTTAACCAGGTTGGTATCTATTTAGAGCCTTATGGGAACAACA
CTTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCAGCGGTCTATGAAATGTGTGACATGCTT
CTTTTGACGAATGAAGTGTCTGTTAAGACCTACCGTGCTGAGTTGGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTCCTAGTACAGCTTGCACAGTGTAAAAATCCCTACAATTGCCCTC
ACGGACGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAAAAAATGTTCCGTCGTATCCAAGAAAATCATACAAGT
CTACGTGACCTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-122)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.902

100

0.699