Detailed information NTG0396915

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FOC73_RS05720
• Genome accession: NZ_CP053998
• Coordinates: 1179098..1181656 (+)
• Length: 852 a.a.
• NCBI ID: WP_004181956.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_771
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1174098..1186656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC73_RS05690 (FOC73_05690)	-	1175280..1175474 (+)	195	WP_004181980.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
FOC73_RS05695 (FOC73_05695)	-	1175501..1175701 (+)	201	WP_004181983.1	hypothetical protein	-
FOC73_RS05700 (FOC73_05700)	-	1175694..1175849 (+)	156	WP_004181943.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
FOC73_RS05705 (FOC73_05705)	argS	1176472..1178163 (-)	1692	WP_004181950.1	arginine--tRNA ligase	-
FOC73_RS05710 (FOC73_05710)	argR	1178318..1178746 (+)	429	WP_170314548.1	arginine repressor	-
FOC73_RS05715 (FOC73_05715)	-	1178746..1179105 (+)	360	WP_002889586.1	YlbF family regulator	-
FOC73_RS05720 (FOC73_05720)	hexA	1179098..1181656 (+)	2559	WP_004181956.1	DNA mismatch repair protein MutS	Machinery gene
FOC73_RS05725 (FOC73_05725)	-	1181690..1182145 (-)	456	WP_004181953.1	DUF3021 domain-containing protein	-
FOC73_RS05730 (FOC73_05730)	-	1182142..1182579 (-)	438	WP_004181975.1	LytTR family DNA-binding domain-containing protein	-
FOC73_RS05735 (FOC73_05735)	-	1182758..1183063 (+)	306	WP_004181965.1	hypothetical protein	-
FOC73_RS05740 (FOC73_05740)	hexB	1183113..1185056 (+)	1944	WP_004181935.1	DNA mismatch repair endonuclease MutL	Machinery gene
FOC73_RS05745 (FOC73_05745)	-	1185187..1185408 (+)	222	WP_002886321.1	hypothetical protein	-
FOC73_RS05750 (FOC73_05750)	ruvA	1185565..1186155 (+)	591	WP_004181981.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95507.71 Da
• Isoelectric Point: 4.6413

>NTDB_id=396915 FOC73_RS05720 WP_004181956.1 1179098..1181656(+) (hexA) [Streptococcus salivarius strain FDAARGOS_771]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQSYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEADEQVLVKQLTLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAAIVERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQ
EKPATETHINEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=396915 FOC73_RS05720 WP_004181956.1 1179098..1181656(+) (hexA) [Streptococcus salivarius strain FDAARGOS_771]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTT
CCGTATGGGTGATTTTTACGAATTATTTTATGATGATGCCGTTAAGGCTGCCCAGATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAACGCCGATAATCCCATTCCTATGGCTGGTGTTCCTTATCATTCAGCTCAATCTTATATTGATGTCTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGT
TCAGGTTATCACGCCAGGAACAGTGGTTGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGG
CCGGAAGTCGATTCGGCCTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTAGTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTT
GGTGAAGCAACTCACCCTTCTACTTTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAG
ACTTGGAAAGCAGTGTAGCGGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGCTCAGCCATTTACAAAAA
GCTCAGCACTATGAGATTAAGGATTACTTGCAGATGTCCTATGCGACCAAGTCGAGTTTGGATTTACTGGAAAATGCTAG
AACAGGTAAGAAACATGGTTCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTACGTACTT
GGATTGATAGACCTTTAGTGAATCAGGCTGCAATCGTGGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTC
GAGCGTAGTGATCTGACTGAGAGTCTTAAAGGGGTTTACGATATTGAGCGCCTGGCCAGCCGTGTTTCCTTTGGAAAGGC
TAATCCTAAAGATTTGATTCAGCTAGGTCATACCCTAGCTCAGGTTCCAGTTATTAAGGCGATTTTGGAGTCTTTTGATG
ACGAGGCCTTGTCACGTCTTTTACAAGAGTTAGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATTGATCCC
GATGCTCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGTGAGGGGACATCATGGATTGCGGATATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGTTTTGGAACTGCTGAGTTGGCTAAGATTGAAGGTGAGATGCTTGAGGCACGTGAAAAGTC
ATCAACGCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTA
AGGCCATTGCGACAGTCGATGTGCTTCAGAGTTTGGCTGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAAT
GATGAGCATCGTATCGTTATTGATCAAGGCCGTCATGCGGTGGTTGAGAAGGTTATGGGTGTTCAGGAGTACATTCCAAA
CACGATTACCTTTGACAGTCAGACCAATGTTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACCTATATGCGTC
AGTTGGCCTTGTCAGTCGTTATGGCTCAGATGGGGGCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCC
ATCTATACACGTATTGGTGCTGCAGATGACTTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAACCA
GGCCATTAAGCGAGCAACACCTAATTCCTTGATTATTTTTGATGAGTTGGGGCGTGGAACAGCCACCTACGATGGTATGG
CTTTGGCCCAGTCTATCATCGAGTTTATTCATGATAAAGTGGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCT
TCACAAGATTGTCGATGGCCCAGCCGATAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACTATCTTGACACAATTAGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAA
GAGAAGCCTGCCACTGAAACGCATATCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGA
GTTACGTGATTTGGACATTTACAATATGACACCGATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.74	100	0.738
mutS	Pseudomonas stutzeri strain ATCC 17587	35.838	100	0.364