Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   STH8232_RS07100 Genome accession   NC_017581
Coordinates   1372242..1372886 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus JIM 8232     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1367242..1377886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STH8232_RS07075 (STH8232_1640) - 1369343..1370341 (-) 999 WP_014621791.1 NAD(P)/FAD-dependent oxidoreductase -
  STH8232_RS07080 (STH8232_1641) trmD 1370343..1371062 (-) 720 WP_002951382.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  STH8232_RS07085 (STH8232_1642) rimM 1371052..1371570 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  STH8232_RS07100 (STH8232_1645) vraR 1372242..1372886 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  STH8232_RS07105 (STH8232_1646) - 1372876..1373886 (-) 1011 WP_014621792.1 sensor histidine kinase -
  STH8232_RS07110 (STH8232_1647) liaF 1373883..1374581 (-) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  STH8232_RS11950 (STH8232_1649) - 1374836..1375003 (-) 168 WP_014621794.1 potassium channel family protein -
  STH8232_RS07115 (STH8232_1651) stkP/pknB 1375641..1377512 (-) 1872 WP_014621795.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=39659 STH8232_RS07100 WP_002951384.1 1372242..1372886(-) (vraR) [Streptococcus thermophilus JIM 8232]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=39659 STH8232_RS07100 WP_002951384.1 1372242..1372886(-) (vraR) [Streptococcus thermophilus JIM 8232]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGATAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment