Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   GH742_RS06985 Genome accession   NZ_CP045732
Coordinates   1493776..1495119 (+) Length   447 a.a.
NCBI ID   WP_203456702.1    Uniprot ID   -
Organism   Legionella sp. MW5194     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1488776..1500119
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GH742_RS06960 (GH742_06925) - 1488911..1489309 (+) 399 WP_203456697.1 CoA-binding protein -
  GH742_RS06965 (GH742_06930) - 1489341..1489712 (+) 372 WP_203456698.1 gamma-glutamylcyclotransferase family protein -
  GH742_RS06970 (GH742_06935) - 1489748..1490212 (-) 465 WP_203456699.1 hypothetical protein -
  GH742_RS06975 (GH742_06940) - 1490369..1492096 (+) 1728 WP_203456700.1 hypothetical protein -
  GH742_RS06980 (GH742_06945) - 1492190..1493779 (+) 1590 WP_203456701.1 PAS domain-containing sensor histidine kinase -
  GH742_RS06985 (GH742_06950) pilR 1493776..1495119 (+) 1344 WP_203456702.1 sigma-54 dependent transcriptional regulator Regulator
  GH742_RS06990 (GH742_06955) - 1495116..1495844 (-) 729 WP_239005304.1 RES family NAD+ phosphorylase -
  GH742_RS06995 (GH742_06960) - 1495841..1496239 (-) 399 WP_203456703.1 MbcA/ParS/Xre antitoxin family protein -
  GH742_RS07000 (GH742_06965) - 1496311..1497660 (-) 1350 WP_239005322.1 M48 family metalloprotease -
  GH742_RS07005 (GH742_06970) ribD 1497919..1498977 (+) 1059 WP_203456705.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  GH742_RS07010 (GH742_06975) - 1498977..1499591 (+) 615 WP_203456706.1 riboflavin synthase -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49499.36 Da        Isoelectric Point: 6.6351

>NTDB_id=396434 GH742_RS06985 WP_203456702.1 1493776..1495119(+) (pilR) [Legionella sp. MW5194]
MSKTKILVVDDEPDICELLSLTLKRMGLNCDTANTYQQGIHYINSEDYSLVLTDMHLPDGDGIELVKYIQKSRPQIPVAV
ITAYGNVDGAVNTLKAGAFDYVSKPIDLPMLKDLVKTALSMQQKPMVSRDDVLLGNSPIMQELRQNIGKLARSQAPVFIL
GESGVGKELVAQLIHSQGPRAEKPFIPVNCGAIPSELMESEFFGHKKGSFTGAIGDKSGLFVAANGGTLFLDEIAELPLA
MQVKLLRAIQEKAIKPIGEHNEIPVDVRILSASHKNLQNEIACGRFRQDLYYRVNVIELRVPTLQERLSDIPLLANHILQ
HLAAEQHRPMEPLSKACIQALQNYHFPGNVRELENILERAMAMCEGNTISVEDLHLPAAPSMPVEDKTVPQPVTPVPKNL
DGSLYEHEKELILSALEKTKWNRTAAAKLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=396434 GH742_RS06985 WP_203456702.1 1493776..1495119(+) (pilR) [Legionella sp. MW5194]
ATGAGTAAGACCAAGATCCTTGTGGTGGATGATGAACCGGACATCTGTGAATTGTTGTCGCTAACCTTAAAGCGCATGGG
CTTAAATTGCGATACGGCCAATACTTATCAGCAAGGCATTCATTACATCAATTCAGAGGATTATTCCCTGGTCCTTACGG
ACATGCATCTCCCTGACGGTGATGGCATTGAACTCGTAAAATACATTCAAAAAAGCCGCCCACAGATTCCAGTGGCCGTC
ATCACGGCCTACGGTAACGTGGACGGTGCGGTCAATACGCTTAAGGCCGGGGCGTTTGATTACGTCTCCAAGCCAATCGA
TCTTCCCATGCTTAAGGATTTGGTAAAAACGGCCTTGTCCATGCAGCAAAAGCCCATGGTTTCACGCGATGATGTGCTGC
TCGGCAATAGCCCCATCATGCAGGAATTAAGACAAAACATCGGTAAACTGGCTCGTAGTCAGGCGCCTGTCTTTATACTT
GGCGAGTCCGGGGTAGGCAAGGAATTGGTGGCGCAGTTGATTCATAGCCAGGGACCGCGTGCCGAAAAACCCTTTATTCC
GGTAAACTGCGGCGCTATCCCCTCGGAGCTCATGGAATCGGAATTTTTTGGCCATAAAAAAGGCAGCTTCACCGGCGCCA
TCGGTGACAAGTCCGGCCTGTTTGTGGCAGCCAATGGCGGCACCCTTTTTTTGGATGAGATTGCCGAGCTGCCCTTGGCC
ATGCAGGTAAAACTTTTACGGGCGATTCAGGAAAAAGCCATTAAGCCCATCGGCGAACACAATGAAATCCCTGTTGATGT
ACGGATTTTGAGCGCCAGTCATAAAAACCTGCAGAATGAAATTGCCTGCGGGCGATTCCGACAGGATTTGTATTACCGTG
TCAATGTGATTGAATTGCGGGTGCCGACTCTCCAGGAACGGTTATCGGATATCCCACTGCTGGCCAACCACATATTGCAG
CATTTGGCCGCTGAGCAGCATCGCCCCATGGAACCCTTGTCCAAGGCCTGTATTCAGGCTCTGCAGAATTATCATTTTCC
CGGTAACGTGCGCGAGCTTGAAAACATTCTGGAGCGGGCAATGGCGATGTGCGAGGGGAATACCATCAGCGTGGAGGATT
TGCATTTACCGGCAGCCCCCAGCATGCCTGTTGAAGATAAGACTGTACCGCAGCCTGTTACCCCCGTGCCGAAAAACCTC
GATGGATCGCTTTACGAACATGAGAAAGAGTTGATTCTAAGCGCCCTTGAAAAAACAAAATGGAACCGCACAGCGGCGGC
TAAACTGTTAGGGGTCAGTTTCAGAACATTAAGGTATCGCCTGAAGAAACTCGGCCTGGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(133-299)

Bacterial regulatory protein, Fis family (HTH_8)

(406-444)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.513

100

0.602
  pilR Acinetobacter baumannii strain A118

50.327

100

0.517

Multiple sequence alignment