Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   GG844_RS12770 Genome accession   NZ_CP045719
Coordinates   1578803..1580932 (-) Length   709 a.a.
NCBI ID   WP_001911453.1    Uniprot ID   -
Organism   Vibrio cholerae O395 substr. TCP2     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1573803..1585932
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GG844_RS12750 (GG844_12750) kdsB 1575096..1575854 (-) 759 WP_000011329.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  GG844_RS12755 (GG844_12755) - 1575854..1576033 (-) 180 WP_000350068.1 Trm112 family protein -
  GG844_RS12760 (GG844_12760) lpxK 1576014..1577021 (-) 1008 WP_002034410.1 tetraacyldisaccharide 4'-kinase -
  GG844_RS12765 (GG844_12765) msbA 1577024..1578772 (-) 1749 WP_000052153.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  GG844_RS12770 (GG844_12770) comEC 1578803..1580932 (-) 2130 WP_001911453.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  GG844_RS12775 (GG844_12775) - 1581055..1581585 (+) 531 WP_001881633.1 DUF2062 domain-containing protein -
  GG844_RS12785 (GG844_12785) lolE 1581700..1582944 (-) 1245 WP_000493010.1 lipoprotein-releasing ABC transporter permease subunit LolE -
  GG844_RS12790 (GG844_12790) lolD 1582945..1583631 (-) 687 WP_001061290.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  GG844_RS12795 (GG844_12795) lolC 1583624..1584832 (-) 1209 WP_000468900.1 lipoprotein-releasing ABC transporter permease subunit LolC -
  GG844_RS12800 (GG844_12800) - 1585008..1585583 (+) 576 WP_000999601.1 PilZ domain-containing protein -

Sequence

Protein


Download         Length: 709 a.a.        Molecular weight: 80009.33 Da        Isoelectric Point: 7.7984

>NTDB_id=396309 GG844_RS12770 WP_001911453.1 1578803..1580932(-) (comEC) [Vibrio cholerae O395 substr. TCP2]
MVLLGYHRVGRQFLGFVAAILTIVLQGNLIRDQSNVLYQAGPDIIIKGRVDSFFTQTRYAYEGFVLIHEVNGQTLNKMTR
PRIRLSAPLLLQPNDRVEFSVTLKPIVGRLNQTGFDLEAHYMAQSVVARAVVKPDTAYQIVQESGIRSSLFFELEQLTHT
SPYQGLILALTFGERKGIDEQEWQALRNSGLIHLVAISGLHIGIAFSVGYFLGLGMMRFHAQLLWSPFVCGALLAVLYAW
LAGFTLPTQRALIMCLLNVALIMLAFPLSALKRILLTLVAVLLWSPFASLSNSFWMSFLAVAIVLYQLASQSQRQVWWKA
LLWAQVFLVCLMAPVTAYFFGGLSVTAVLYNLVFIPWFSLVIVPALFLGLLLMVVWPSVAAAYWPWVDWTFLPLDWALQF
ADVGWWVVPSKVQGVVAASVAILLLYRFMSLKACSLLLGMIGLWWWFPSLTPLWRMDVLDVGHGLAIVIEQDERAIVYDT
GSSWPGGSYVQSVIEPMLQQRGLRQVDGVILSHLDNDHAGDWQGLAERWQPNWIRASQLGTEFMPCIRGESWQWQSLHFT
VLWPPQAVSRAYNQHSCVIRMTDTQSNHSVLLSGDVTAMGEWLLARDGAQLQSEVMIVPHHGSKTSSTAEFIAQVNPKLA
IASVAKDNRWNLPNPQVVARYQAQQVEWLDTGHAGQISLFFYLDQLDWFTQRSLGWQPWYRQMLRKGVE

Nucleotide


Download         Length: 2130 bp        

>NTDB_id=396309 GG844_RS12770 WP_001911453.1 1578803..1580932(-) (comEC) [Vibrio cholerae O395 substr. TCP2]
ATGGTTTTGCTCGGTTATCACCGAGTTGGCCGTCAATTCCTTGGCTTCGTGGCTGCCATACTAACCATTGTGCTACAGGG
CAACCTTATACGAGATCAATCCAATGTGCTCTATCAAGCAGGGCCGGATATTATCATAAAAGGCCGTGTTGACAGCTTTT
TTACGCAAACTCGTTACGCTTATGAGGGTTTTGTCCTCATTCATGAAGTGAATGGACAAACCTTAAACAAAATGACTCGC
CCTCGCATACGTTTAAGTGCCCCTTTACTGTTACAACCCAATGATCGCGTCGAATTTTCGGTAACTCTCAAGCCGATAGT
GGGTCGACTCAACCAAACCGGCTTTGATTTAGAAGCGCATTACATGGCGCAATCTGTCGTCGCACGAGCGGTCGTAAAAC
CTGACACTGCTTATCAAATTGTGCAAGAGAGTGGCATAAGGTCAAGTTTGTTTTTTGAGCTAGAGCAATTAACGCATACC
AGCCCATACCAAGGATTGATCTTAGCCCTGACGTTTGGCGAGCGAAAAGGTATTGATGAGCAAGAGTGGCAAGCCTTACG
CAATAGTGGCTTAATTCATTTAGTGGCCATTTCGGGGCTGCACATTGGTATCGCTTTTAGCGTGGGGTATTTTCTCGGGC
TCGGCATGATGCGTTTTCATGCTCAGTTATTGTGGTCCCCTTTTGTGTGTGGGGCTTTACTGGCGGTGCTCTACGCTTGG
CTGGCCGGATTTACGTTGCCTACTCAGCGTGCATTGATTATGTGCTTACTCAATGTGGCGTTGATCATGTTGGCTTTTCC
TCTTTCCGCGCTCAAGCGGATTCTACTCACCTTAGTCGCGGTCTTGCTTTGGTCGCCATTCGCCTCACTTTCAAACAGTT
TCTGGATGTCGTTTTTGGCGGTCGCGATTGTTCTCTACCAATTAGCCAGTCAAAGCCAGCGTCAGGTGTGGTGGAAAGCT
CTTCTTTGGGCGCAGGTGTTCCTCGTCTGTTTAATGGCACCGGTCACGGCCTATTTTTTCGGTGGCTTAAGCGTAACGGC
AGTTCTGTACAATTTGGTGTTTATTCCTTGGTTTTCGTTGGTGATTGTCCCAGCTTTGTTTTTGGGTCTATTACTCATGG
TGGTATGGCCTAGTGTGGCCGCCGCTTACTGGCCTTGGGTGGATTGGACGTTTTTACCGCTCGATTGGGCTTTGCAGTTT
GCCGATGTAGGCTGGTGGGTGGTCCCCAGCAAAGTACAAGGTGTGGTCGCAGCGAGTGTGGCCATCCTCTTGCTTTATCG
ATTTATGAGCCTAAAAGCCTGCAGCTTATTATTGGGTATGATTGGCTTATGGTGGTGGTTTCCCTCTCTCACTCCACTTT
GGCGAATGGATGTGCTGGATGTTGGACATGGCTTGGCGATTGTGATTGAGCAAGATGAGCGAGCAATTGTCTACGATACA
GGCAGCAGTTGGCCGGGAGGCAGCTATGTGCAAAGCGTGATTGAGCCTATGCTCCAACAGCGGGGGCTACGCCAAGTGGA
TGGAGTGATTTTAAGTCATCTTGATAATGATCATGCGGGTGATTGGCAAGGTTTAGCTGAGCGCTGGCAACCCAATTGGA
TTCGTGCCAGCCAACTCGGGACAGAGTTTATGCCTTGTATCCGTGGTGAAAGCTGGCAGTGGCAATCTCTCCATTTTACG
GTGTTATGGCCACCACAAGCGGTTAGCCGAGCGTACAACCAGCATTCGTGTGTGATTCGTATGACCGATACTCAGTCTAA
CCATTCTGTACTGCTCTCCGGGGATGTCACAGCCATGGGGGAGTGGCTGCTTGCTCGCGACGGAGCGCAACTGCAAAGTG
AGGTGATGATCGTGCCGCACCACGGCAGTAAAACATCGTCCACCGCAGAGTTTATTGCCCAAGTGAATCCCAAACTTGCG
ATTGCTTCTGTGGCGAAAGATAACCGCTGGAATTTGCCTAATCCGCAAGTCGTGGCACGTTATCAAGCTCAGCAAGTTGA
GTGGCTAGATACTGGACACGCTGGGCAAATTAGCCTCTTTTTCTATCTAGATCAGCTGGATTGGTTTACCCAGCGTAGCC
TTGGCTGGCAGCCTTGGTATAGGCAGATGCTGCGTAAAGGAGTAGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(6-135)

Competence protein (Competence)

(170-426)

Metallo-beta-lactamase superfamily (Lactamase_B)

(461-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Vibrio cholerae strain A1552

100

100

1
  comEC Vibrio parahaemolyticus RIMD 2210633

41.433

100

0.416
  comEC Vibrio campbellii strain DS40M4

41.301

99.718

0.412

Multiple sequence alignment