Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   HPM97_RS22620 Genome accession   NZ_CP053851
Coordinates   4803110..4803766 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CE1803A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4798110..4808766
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPM97_RS22590 (HPM97_22585) yecA 4799361..4800026 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  HPM97_RS22610 (HPM97_22605) pgsA 4800676..4801224 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HPM97_RS22615 (HPM97_22610) uvrC 4801281..4803113 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  HPM97_RS22620 (HPM97_22615) letA 4803110..4803766 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  HPM97_RS22625 (HPM97_22620) yecU 4804061..4804237 (+) 177 WP_032245964.1 protein YecU -
  HPM97_RS22630 (HPM97_22625) yecF 4804224..4804448 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  HPM97_RS22635 (HPM97_22630) sdiA 4804515..4805237 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  HPM97_RS22640 (HPM97_22635) tcyN 4805467..4806219 (-) 753 WP_063624912.1 L-cystine ABC transporter ATP-binding protein TcyN -
  HPM97_RS22645 (HPM97_22640) tcyL 4806216..4806884 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  HPM97_RS22650 (HPM97_22645) dcyD 4806899..4807885 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=395841 HPM97_RS22620 WP_000611328.1 4803110..4803766(-) (letA) [Escherichia coli strain CE1803A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=395841 HPM97_RS22620 WP_000611328.1 4803110..4803766(-) (letA) [Escherichia coli strain CE1803A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCAACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGTCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment