Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   HICON_RS04840 Genome accession   NC_014922
Coordinates   951932..952624 (+) Length   230 a.a.
NCBI ID   WP_013525531.1    Uniprot ID   A0AAV2U3Y4
Organism   Haemophilus influenzae F3047     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 946932..957624
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HICON_RS04820 (HICON_11750) ampD 948206..948766 (-) 561 WP_006996183.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  HICON_RS04825 (HICON_11760) pilA 948881..949330 (+) 450 WP_006996184.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  HICON_RS04830 (HICON_11770) pilB 949327..950721 (+) 1395 WP_013525533.1 GspE/PulE family protein Machinery gene
  HICON_RS04835 (HICON_11780) pilC 950718..951935 (+) 1218 WP_013525532.1 type II secretion system F family protein Machinery gene
  HICON_RS04840 (HICON_11790) pilD 951932..952624 (+) 693 WP_013525531.1 prepilin peptidase Machinery gene
  HICON_RS04845 (HICON_11800) rho 952679..953941 (-) 1263 WP_005666690.1 transcription termination factor Rho -
  HICON_RS04850 (HICON_11810) metJ 954189..954506 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  HICON_RS04855 (HICON_11820) cueR 954520..954906 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  HICON_RS04860 (HICON_11830) - 954983..955189 (+) 207 WP_013525530.1 heavy-metal-associated domain-containing protein -
  HICON_RS04865 (HICON_11840) - 955264..955470 (+) 207 WP_013525530.1 heavy-metal-associated domain-containing protein -
  HICON_RS04870 (HICON_11850) - 955445..957613 (+) 2169 WP_013525529.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26800.82 Da        Isoelectric Point: 8.8532

>NTDB_id=39463 HICON_RS04840 WP_013525531.1 951932..952624(+) (pilD) [Haemophilus influenzae F3047]
MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNFLPFQSSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWFGLTLLILWAISYLDWHYQLISTTLCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIQLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYWY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=39463 HICON_RS04840 WP_013525531.1 951932..952624(+) (pilD) [Haemophilus influenzae F3047]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTGCCATTTCAGTCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGTTCGGACTCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACTACACTCTGTTTATGGTTACTTACAATCGGTTTATTTGGGGCAGACAATAACTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCAGTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATAATTTATTTCGTCAAATATTACTGGTATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

90.435

100

0.904
  pilD Haemophilus influenzae Rd KW20

90

100

0.9

Multiple sequence alignment