Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GE022_RS09965 Genome accession   NZ_CP053790
Coordinates   2060665..2062647 (-) Length   660 a.a.
NCBI ID   WP_039994902.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2055665..2067647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS09940 (GE022_009930) cinA 2056510..2057781 (-) 1272 WP_164405491.1 competence/damage-inducible protein A Machinery gene
  GE022_RS09945 (GE022_009935) - 2057898..2058251 (-) 354 WP_164228190.1 VOC family protein -
  GE022_RS09950 (GE022_009940) - 2058254..2058826 (-) 573 WP_164405490.1 DNA-3-methyladenine glycosylase I -
  GE022_RS09955 (GE022_009945) ruvA 2058836..2059432 (-) 597 WP_164405489.1 Holliday junction branch migration protein RuvA Machinery gene
  GE022_RS09960 (GE022_009950) - 2059416..2060654 (-) 1239 WP_164405488.1 MDR family MFS transporter -
  GE022_RS09965 (GE022_009955) hexB 2060665..2062647 (-) 1983 WP_039994902.1 DNA mismatch repair endonuclease MutL Machinery gene
  GE022_RS10785 - 2062741..2063653 (-) 913 Protein_1926 tyrosine-type recombinase/integrase -
  GE022_RS09980 (GE022_009970) - 2064279..2064854 (-) 576 WP_164405487.1 TMEM175 family protein -
  GE022_RS09985 (GE022_009975) - 2064916..2065404 (-) 489 WP_164405486.1 prolyl-tRNA synthetase associated domain-containing protein -
  GE022_RS09990 (GE022_009980) - 2065439..2066071 (-) 633 WP_164405485.1 helix-turn-helix domain-containing protein -
  GE022_RS09995 (GE022_009985) - 2066433..2066984 (-) 552 WP_164405484.1 hypothetical protein -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74407.98 Da        Isoelectric Point: 5.7465

>NTDB_id=394562 GE022_RS09965 WP_039994902.1 2060665..2062647(-) (hexB) [Streptococcus canis strain HL_77_2]
MTNIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQITIEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEAIHGSILVATGGKIETLEPISTPIGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIAIQLDPYLADVNVHPTKQEVRISKERELMALISA
AISESLREQDLIPDALENLAKSSTRHFSKPEQTQLPLQSRGLYYDPQKNDFFVKESAVAEKMPETDFHYGDVDNCVKVEK
TESLPHSEEDTGPSSVKHASRPQDSLVNPDHPDFDLKNKQKLSQMLDRLENEEKSAFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGDVDSSLQQLLVPYLFEFSGSDFINLQEKMTLLNEVGIFLEVYGHNTFILREHPIWMKEE
EIESGVYEMCDMLLLTNEVSVKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=394562 GE022_RS09965 WP_039994902.1 2060665..2062647(-) (hexB) [Streptococcus canis strain HL_77_2]
ATGACAAACATTATTGAATTACCGGAAGTTCTCGCCAACCAAATCGCAGCTGGTGAGGTTGTAGAAAGACCAGCAAGTGT
TGTCAAGGAGTTGGTTGAGAATGCTATTGATGCTAAAAGTAGCCAGATTACCATTGAAATTGAAGAGTCTGGTCTTAAAA
TGATACAGATTACAGACAATGGTGAAGGGATGTCACATGAAGACCTACCCTTGAGTTTGCGTCGTCATGCCACCAGTAAA
ATTAAAAGTCAGAGTGACCTTTTTCGAATTAGGACGCTTGGATTTCGAGGAGAAGCTTTACCGTCGGTTGCCTCCATTAG
TAAAATCACGATAAAAACTGCAACAAAAGAAGCTATACATGGCTCTATTCTCGTTGCTACGGGTGGGAAAATTGAGACGC
TTGAACCAATCTCAACACCTATTGGAACCAAAATTAAGGTTGAAAACCTTTTTTACAACACTCCTGCCCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAATTAGCTCACATTGTAGATGTGGTCAATCGGTTGAGTTTGGCTCACCCAGAAGTTGCTTT
TACACTGATTAGTGATGGTCGTCAATTAACTCAGACCTCAGGGACTGGCGATTTGCGCCAAGCTATTGCTGGTATTTACG
GCTTGAATACTGCGAAGAAAATGATTGCTATCTCTAATGCTGATCTGGATTTTGAAGTGTCTGGATATGTCAGTTTACCA
GAGTTGACACGTGCTAATCGAAACTATATGACAATTTTAATCAATGGACGCTACATTAAAAACTTCTTGCTCAATCGAGC
TATCTTAGATGGTTATGGTTCTAAATTGATGGTTGGACGTTTTCCGATTGTTGTGATTGCTATTCAGCTTGATCCTTACT
TAGCTGATGTCAATGTCCACCCCACAAAGCAAGAGGTTCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATCAGTGCA
GCTATTTCTGAAAGCCTTAGGGAACAAGACTTAATTCCAGATGCACTTGAAAATTTAGCCAAATCAAGCACACGACATTT
TTCCAAACCAGAGCAAACACAACTTCCTTTACAGTCTAGGGGACTTTACTATGATCCGCAAAAGAATGACTTTTTTGTCA
AAGAATCGGCTGTCGCGGAAAAAATGCCTGAAACTGATTTTCATTACGGCGATGTTGACAACTGTGTAAAGGTTGAAAAG
ACAGAGTCGCTACCTCACTCAGAAGAAGACACAGGACCTTCTTCAGTAAAGCATGCTAGCCGTCCCCAAGATAGTTTAGT
GAATCCTGATCATCCTGACTTTGACTTAAAAAATAAACAAAAGTTATCTCAAATGTTGGATCGCTTGGAAAATGAAGAAA
AATCAGCATTTCCTGAATTAGATTATTTTGGTCAGATGCATGGGACTTATCTCTTTGCTCAAGGCAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATATGAATATTATCGTGATAAGATTGGCGATGTTGACAGTAGTTT
ACAGCAGTTGTTAGTGCCTTACTTATTTGAGTTTTCTGGTTCGGATTTCATTAATTTACAGGAAAAAATGACACTTCTAA
ATGAAGTCGGTATCTTTCTGGAAGTTTATGGGCACAATACTTTCATTCTGAGAGAGCATCCTATTTGGATGAAAGAAGAA
GAGATTGAATCTGGTGTCTATGAAATGTGTGATATGTTACTTTTGACAAATGAGGTATCTGTCAAAACTTATCGAGCAGA
GTTAGCGATTATGATGAGCTGTAAACGGTCTATTAAAGCTAATCACAGTTTAGATGATTATTCAGCAAGGAATCTTTTGC
TGCAATTAGCGCAATGCCAAAATCCTTATAACTGTCCTCATGGCAGACCCGTTTTGATTAACTTTAGCAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCACACTAGTCTACGAGAATTAGGAAAATATTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(462-604)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

68.477

100

0.688