Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GE023_RS08140 Genome accession   NZ_CP053789
Coordinates   1634937..1635578 (-) Length   213 a.a.
NCBI ID   WP_003044709.1    Uniprot ID   A0A2D4DP75
Organism   Streptococcus canis strain HL_98_2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1629937..1640578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS08120 (GE023_008115) - 1631289..1631921 (+) 633 WP_159305988.1 YigZ family protein -
  GE023_RS08125 (GE023_008120) cysK 1632039..1632974 (+) 936 WP_003044700.1 cysteine synthase A -
  GE023_RS08130 (GE023_008125) - 1633141..1633500 (-) 360 WP_003044703.1 S1 RNA-binding domain-containing protein -
  GE023_RS08135 (GE023_008130) - 1633500..1634900 (-) 1401 WP_125073665.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  GE023_RS08140 (GE023_008135) vraR 1634937..1635578 (-) 642 WP_003044709.1 response regulator transcription factor Regulator
  GE023_RS08145 (GE023_008140) - 1635571..1636575 (-) 1005 WP_159305987.1 sensor histidine kinase -
  GE023_RS08150 (GE023_008145) liaF 1636572..1637264 (-) 693 WP_093998979.1 cell wall-active antibiotics response protein LiaF -
  GE023_RS08155 (GE023_008150) pknB 1637391..1639286 (-) 1896 WP_099982918.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  GE023_RS08160 (GE023_008155) - 1639283..1640023 (-) 741 WP_003044720.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23810.42 Da        Isoelectric Point: 4.8940

>NTDB_id=394435 GE023_RS08140 WP_003044709.1 1634937..1635578(-) (vraR) [Streptococcus canis strain HL_98_2]
MRKISVILVDDHEMVRMGLKSFLNLQADIDVIGEASNGREGVDLALTLKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=394435 GE023_RS08140 WP_003044709.1 1634937..1635578(-) (vraR) [Streptococcus canis strain HL_98_2]
ATGCGTAAAATAAGTGTAATTTTAGTGGATGATCATGAAATGGTTCGCATGGGACTCAAAAGTTTTTTGAATTTACAGGC
TGATATTGATGTGATCGGTGAAGCTTCCAATGGGCGTGAAGGGGTCGATTTGGCCTTGACTTTGAAACCAGATGTGTTGG
TGATGGACTTGGTGATGCCAGAGTTAGGTGGTGTAGAAGCGACCTTGGAAATTCTTGACAAGTGGAAAGATGCCAAGGTA
CTGGTTTTAACCTCCTACTTAGATAATGAAAAAATTTACCCTGTCATTGATGCAGGTGCCAAGGGGTATATGTTAAAAAC
ATCGAGTGCAGCTGAAATTTTAAATGCCATTCGCAAGGTTTCAAAGGGAGAACTAGCCATTGAAACAGAGGTTGACAAAA
AAATTAAGGCGCATGATCAACACCCTGACTTGCACGAGGAGTTAACCGCGCGTGAGTATGATATTTTACACCTTTTAGCT
AAAGGGTATGATAATCAGACCATCGCTGATGAACTCTTTATTTCCTTAAAAACCGTCAAAACTCATGTGTCCAATATCCT
AGCCAAGTTAGAAGTTGATGATCGAACCCAAGCAGTTGTCTATGCTTTTCGACACCATTTAGTCCCCCAAGACGATAATT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2D4DP75

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.942

96.714

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376