Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   GBR75_RS06015 Genome accession   NZ_CP045468
Coordinates   1244977..1245849 (+) Length   290 a.a.
NCBI ID   WP_000620183.1    Uniprot ID   A0A6B1RG35
Organism   Staphylococcus aureus strain SAW1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1239977..1250849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GBR75_RS05990 (GBR75_06105) - 1240122..1240889 (+) 768 WP_160210514.1 ribonuclease HII -
  GBR75_RS05995 (GBR75_06110) sucC 1240998..1242164 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  GBR75_RS06000 (GBR75_06115) sucD 1242186..1243094 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  GBR75_RS06005 (GBR75_06120) - 1243381..1243533 (+) 153 Protein_1172 cell wall hydrolase -
  GBR75_RS06010 (GBR75_06125) fmhC 1243561..1244805 (+) 1245 WP_000672856.1 FemA/FemB family glycyltransferase FmhC -
  GBR75_RS06015 (GBR75_06130) dprA 1244977..1245849 (+) 873 WP_000620183.1 DNA-processing protein DprA Machinery gene
  GBR75_RS06020 (GBR75_06135) topA 1246022..1248097 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  GBR75_RS06025 (GBR75_06140) trmFO 1248253..1249560 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33532.95 Da        Isoelectric Point: 9.5191

>NTDB_id=394380 GBR75_RS06015 WP_000620183.1 1244977..1245849(+) (dprA) [Staphylococcus aureus strain SAW1]
MIRLFLLKLYWAHFSTKQIHQFLMAYPNVIKEGGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDTEYPVLLKEIYQFPLLLFYKGNINLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQIHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=394380 GBR75_RS06015 WP_000620183.1 1244977..1245849(+) (dprA) [Staphylococcus aureus strain SAW1]
TTGATTAGACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGGGGGCAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATACTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
AAATTTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATAGCAGTTTTAGCCTTTGGCCATCAAATACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGAGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6B1RG35

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

98.276

100

0.983
  dprA Staphylococcus aureus N315

97.931

100

0.979

Multiple sequence alignment