Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   HPC60_RS11570 Genome accession   NZ_CP053671
Coordinates   2280998..2281663 (+) Length   221 a.a.
NCBI ID   WP_023188627.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis strain G121     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2275998..2286663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPC60_RS11540 (HPC60_06290) - 2277142..2277468 (-) 327 WP_025016835.1 lactococcin 972 family bacteriocin -
  HPC60_RS11545 (HPC60_06295) - 2277768..2278496 (-) 729 WP_023188628.1 LytTR family transcriptional regulator DNA-binding domain-containing protein -
  HPC60_RS11550 (HPC60_06300) - 2278688..2278909 (+) 222 WP_010906270.1 YqgQ family protein -
  HPC60_RS11555 (HPC60_06305) - 2278942..2279913 (+) 972 WP_017865099.1 ROK family glucokinase -
  HPC60_RS11560 (HPC60_06310) - 2279916..2280302 (+) 387 WP_004254540.1 rhodanese-like domain-containing protein -
  HPC60_RS11565 (HPC60_06315) - 2280385..2280831 (-) 447 WP_004254538.1 DNA starvation/stationary phase protection protein -
  HPC60_RS11570 (HPC60_06320) cclA/cilC 2280998..2281663 (+) 666 WP_023188627.1 A24 family peptidase Machinery gene
  HPC60_RS11575 (HPC60_06325) dinB 2281614..2282708 (-) 1095 WP_023188626.1 DNA polymerase IV -
  HPC60_RS11580 (HPC60_06330) - 2282787..2283278 (-) 492 WP_023188625.1 prolyl-tRNA synthetase associated domain-containing protein -
  HPC60_RS11585 (HPC60_06335) - 2283357..2284850 (-) 1494 WP_015427125.1 basic amino acid/polyamine antiporter -
  HPC60_RS11590 (HPC60_06340) - 2285042..2286172 (-) 1131 WP_014570781.1 aminotransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25655.77 Da        Isoelectric Point: 8.3252

>NTDB_id=393383 HPC60_RS11570 WP_023188627.1 2280998..2281663(+) (cclA/cilC) [Lactococcus lactis subsp. lactis strain G121]
MDILFIFVIGSIFGSFFGLIVDRIPLRKSIIFGRSHCDSCQQLLAYRDLIPIFSQISSGSHCRYCKSEITYLYVFLEFSS
ALIFVLAWVNYLKPSQFLLIILSLILSAFDYRQHSFPFVIWFIFALSFILIFPLSPLFYFWLILAVLAEKFNLRVGSGDF
LWFFTASFSLTFLNEMLLLQIACSLGIIYYLITKKRVEIAFIPFLTIAYLMLLFGHQILSP

Nucleotide


Download         Length: 666 bp        

>NTDB_id=393383 HPC60_RS11570 WP_023188627.1 2280998..2281663(+) (cclA/cilC) [Lactococcus lactis subsp. lactis strain G121]
ATGGACATTTTATTTATATTTGTAATTGGAAGTATTTTTGGCTCCTTTTTTGGCTTAATAGTTGACCGTATTCCACTAAG
AAAATCAATTATTTTTGGACGCTCACATTGTGATTCTTGTCAGCAACTTTTAGCCTATCGTGATCTAATTCCTATTTTTT
CTCAAATAAGCTCTGGCTCACATTGCCGTTATTGTAAAAGTGAAATTACATATTTATATGTTTTTTTGGAGTTCTCATCA
GCTTTAATTTTTGTTTTAGCTTGGGTAAATTATCTTAAACCTAGTCAATTTTTACTGATTATTCTTTCACTAATTTTATC
TGCTTTTGATTATCGTCAGCACAGTTTTCCTTTTGTTATCTGGTTTATTTTTGCACTCAGTTTTATTTTAATATTTCCTC
TTTCTCCCCTTTTCTATTTTTGGCTTATTTTAGCCGTCTTAGCTGAAAAATTCAATTTAAGAGTTGGCAGCGGTGATTTT
TTATGGTTTTTTACCGCTTCATTTTCTCTAACTTTCTTAAACGAAATGCTGCTCCTTCAAATCGCTTGTTCACTTGGTAT
CATTTATTATCTAATCACAAAAAAACGAGTTGAAATTGCCTTCATCCCGTTTCTAACTATTGCATATCTAATGTTGCTTT
TTGGGCACCAAATTCTGTCACCGTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

36.986

99.095

0.367
  cclA/cilC Streptococcus pneumoniae Rx1

37.209

97.285

0.362
  cclA/cilC Streptococcus pneumoniae D39

37.209

97.285

0.362
  cclA/cilC Streptococcus pneumoniae R6

37.209

97.285

0.362