Detailed information NTG0393351

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: GCS73_RS06655
• Genome accession: NZ_CP045308
• Coordinates: 1443556..1446288 (-)
• Length: 910 a.a.
• NCBI ID: WP_012979015.1
• Uniprot ID: -
• Organism: Legionella longbeachae strain B41211CHC
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1438556..1451288

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GCS73_RS06630 (GCS73_06560)	-	1438699..1439235 (+)	537	Protein_1230	IS5 family transposase	-
GCS73_RS06635 (GCS73_06570)	-	1439408..1440808 (-)	1401	WP_003632056.1	APC family permease	-
GCS73_RS06640 (GCS73_06575)	-	1441139..1441462 (-)	324	WP_003632054.1	BolA family protein	-
GCS73_RS06645 (GCS73_06580)	pilA2	1441544..1441978 (-)	435	WP_003632053.1	pilin	Machinery gene
GCS73_RS06650 (GCS73_06585)	-	1442271..1443515 (-)	1245	WP_003632052.1	6-phosphofructokinase	-
GCS73_RS06655 (GCS73_06590)	letS	1443556..1446288 (-)	2733	WP_012979015.1	two-component system sensor histidine kinase LetS	Regulator
GCS73_RS06660 (GCS73_06595)	gltX	1446420..1447835 (+)	1416	WP_003632050.1	glutamate--tRNA ligase	-
GCS73_RS06665 (GCS73_06600)	-	1447832..1449106 (+)	1275	WP_003632048.1	serine hydrolase domain-containing protein	-
GCS73_RS06670 (GCS73_06605)	-	1449246..1450229 (+)	984	WP_003632046.1	hypothetical protein	-
GCS73_RS06675 (GCS73_06610)	gstA	1450288..1450890 (+)	603	WP_003632045.1	glutathione transferase GstA	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 102712.32 Da
• Isoelectric Point: 7.7707

>NTDB_id=393351 GCS73_RS06655 WP_012979015.1 1443556..1446288(-) (letS) [Legionella longbeachae strain B41211CHC]
MKSIGIKYQLRITTLIPVFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRGDDRTLQGLINASTINPE
VKALAFYSSDGQLLAYRGGKHSLNKPFTAPKFTGDYIKSKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMASRADDI
LGWLSLDIDTRSMIIKRYQMLIVTIFITLFGLLVGLTIHYFLSKQIYLPISRLRRSMKQILRNEFETEIKTTSSGELGII
EQGCSHLQKKHLETIRDLNHHIEVATADLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLALAAPNAHKKGIDLIPITEL
NVPKIVLGDPFRVKQFISNLVTNAVKFTDHGYVLIRTNVEQETEKDYTLCITITDTGLGISPEDQSKLFTAFNQADTSIT
RRYGGSGLGLVICKKLCEEMKGRITFASELNKGSVFTAYIKVEKLVAYEVERNQVHPFAHFKMLCFDDNPMQLEALCNGL
GYWGIKCIAVSSLNQLAKELKDNKDCQIAFLNINKGYEQQITKLIAEHNYFPYVLISKWLINDYAALGAQGFLYKPISIQ
KLQDIIESLTNQENIEKSVNHELEGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTRSNITSVDNGEIAVSVCNEKKFSL
ILLDLRMPKINGLEAARLIRQKSEFNRHTPIVLISANGRDVNDIDLKKAGVNFCLQKPIDEKQLLIQILRIADKAKHSAI
DWQLCIQKASGNQSLAEEFLARFVEELLKNREEFIQLMHEKNVKQLGEVAHKLHGACCFSGVPTLQKKVVQVEKLAAHAA
SIEELAMPFAELIQSIDAVISEYENQKIKT

Nucleotide

• Length: 2733 bp

>NTDB_id=393351 GCS73_RS06655 WP_012979015.1 1443556..1446288(-) (letS) [Legionella longbeachae strain B41211CHC]
TTGAAAAGCATTGGTATAAAGTATCAACTACGAATTACTACTTTAATTCCTGTTTTTCTCGTCGCCCTACTCCTTGCCAT
TTTTTATAATGGGTTGTTTGGTAATGACTTAAAACAACACATGTCTCGCCTTGGTGAAGCATATATCCGGCAATTACTTC
CGGCTGCCCAGTATGCTATGCTGCGTGGGGACGATCGAACCTTACAAGGCCTAATCAATGCCTCTACAATCAACCCCGAA
GTTAAAGCACTTGCTTTTTATAGTAGCGACGGTCAACTCCTTGCTTATCGTGGTGGCAAACATTCGCTTAACAAACCATT
TACTGCACCTAAATTCACCGGGGATTACATCAAAAGTAAACAAATTAACCCCTTTACTATTAATTTTATCGCGCCGGTTA
CGATTCCAAAATTCAATTTGTATTCCAATTCTTCTTTTAAAAATATTTTAAGTCCCATGGCATCCCGTGCTGATGACATT
CTTGGGTGGTTGTCTCTTGATATTGATACTCGTTCAATGATAATCAAACGTTATCAGATGCTTATTGTCACTATTTTCAT
TACTTTATTTGGGTTATTAGTAGGATTAACCATTCACTACTTTCTCTCCAAACAAATTTATTTACCTATTTCTCGTTTAC
GACGAAGCATGAAACAAATTTTGCGTAACGAGTTTGAAACAGAAATAAAAACAACAAGCTCTGGTGAATTAGGCATAATT
GAACAGGGATGTTCCCATTTGCAAAAAAAACACCTTGAAACGATACGTGATCTAAACCACCACATTGAGGTAGCCACGGC
TGATTTACAACAAAGTTTGGAACTCTTGGAAGAAAAAAATATTGAACTCTCCCTCGAAAAGAAAAAAATTGAAGAAAAAA
GTCGGCAAAAATCTGAGTTCATAGCCAATATGAGCCATGAAATTCGTACGCCGATGAATGGAGTTATTGGTTTTACTAAC
GTTTTGCTTGAAAGTAAACTCGATCCATTACAACTGGATTATGTAAAAACAATTAAATCATCAGCACAAGACTTATTAGG
GATTATCAATGATATTCTCGATTTCTCAAAAATTGATGCAGGAAAACTTCATCTCGATTGTATTCCGTTAAATATTCGCC
ATTGTATTGATGAAGTACTCGCTCTTGCAGCACCTAATGCCCATAAGAAGGGAATCGACTTAATTCCTATAACAGAACTA
AACGTACCTAAAATTGTTTTAGGGGATCCCTTCAGGGTGAAACAATTCATTAGCAACCTGGTAACTAATGCTGTTAAATT
TACCGATCATGGATATGTATTAATCCGTACCAATGTGGAGCAGGAAACGGAAAAAGATTACACTTTATGCATTACAATTA
CTGATACAGGCCTAGGTATTTCTCCTGAAGACCAAAGCAAATTATTTACAGCCTTCAATCAAGCAGATACAAGTATTACC
CGTCGTTATGGGGGCTCCGGACTTGGCTTGGTAATTTGCAAAAAACTCTGCGAGGAAATGAAAGGCCGTATTACTTTCGC
CAGCGAACTCAACAAAGGTTCTGTATTTACCGCTTATATCAAGGTTGAAAAATTGGTTGCTTATGAAGTTGAAAGAAATC
AAGTGCATCCTTTTGCGCATTTCAAAATGCTTTGTTTTGACGATAACCCAATGCAATTGGAAGCCCTGTGTAATGGCTTA
GGATATTGGGGAATAAAATGTATCGCTGTAAGTTCACTCAATCAACTCGCGAAAGAGCTGAAAGACAATAAAGACTGCCA
AATCGCATTTCTTAATATCAATAAAGGCTACGAACAGCAAATTACCAAGCTAATAGCCGAACATAATTATTTTCCCTATG
TATTAATCTCTAAATGGCTTATCAATGATTATGCAGCACTTGGAGCACAGGGATTTTTATATAAACCCATTAGCATCCAA
AAACTCCAAGATATTATTGAGTCATTAACAAATCAGGAAAATATTGAAAAGTCGGTTAACCATGAATTAGAAGGTTTAAG
GGAACAATTACGTTTCTTACATCCTGATCTTCTTATAGCTGAAGATAATCCAGTAAATAAAATGCTTCTTGATTCTTTAT
TAGGGACTCGTTCCAACATTACATCCGTTGATAATGGCGAAATAGCCGTATCGGTGTGTAATGAAAAGAAATTCAGTCTC
ATCTTGCTTGATTTGCGTATGCCTAAAATAAATGGCTTGGAAGCTGCTCGACTTATCCGCCAAAAATCAGAGTTTAATCG
TCATACACCAATAGTATTGATTAGTGCAAATGGTAGAGATGTTAATGATATTGATTTAAAGAAAGCTGGTGTAAATTTTT
GTTTGCAAAAGCCTATAGACGAAAAACAATTATTAATTCAAATTTTACGTATTGCAGATAAAGCAAAACACTCAGCAATA
GATTGGCAACTATGTATTCAAAAAGCCTCAGGAAATCAATCACTTGCTGAAGAGTTTCTTGCTCGGTTTGTAGAAGAATT
GCTTAAAAATCGTGAAGAGTTTATCCAATTAATGCATGAAAAAAATGTGAAGCAACTGGGCGAAGTGGCGCATAAACTTC
ATGGAGCATGTTGTTTTAGTGGTGTTCCCACGTTACAAAAAAAAGTAGTTCAGGTTGAAAAACTTGCTGCGCATGCTGCT
TCAATCGAAGAGTTAGCTATGCCTTTCGCAGAATTAATTCAAAGCATCGATGCGGTGATTAGTGAATACGAAAATCAAAA
AATAAAAACTTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Single cache domain 4 (sCache_4) (35-179)

• Hpt domain (Hpt) (818-899)

• Response regulator receiver domain (Response_reg) (678-786)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	77.925	99.56	0.776