Detailed information NTG0393314

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: GCB94_RS07385
• Genome accession: NZ_CP045306
• Coordinates: 1446413..1449148 (-)
• Length: 911 a.a.
• NCBI ID: WP_085956275.1
• Uniprot ID: -
• Organism: Legionella longbeachae strain B1445CHC
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1441413..1454148

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GCB94_RS07360 (GCB94_07325)	-	1441556..1442089 (+)	534	Protein_1228	IS5 family transposase	-
GCB94_RS07365 (GCB94_07335)	-	1442265..1443665 (-)	1401	WP_003632056.1	APC family permease	-
GCB94_RS07370 (GCB94_07340)	-	1443996..1444319 (-)	324	WP_003632054.1	BolA family protein	-
GCB94_RS07375 (GCB94_07345)	pilA2	1444401..1444835 (-)	435	WP_003632053.1	pilin	Machinery gene
GCB94_RS07380 (GCB94_07350)	-	1445128..1446372 (-)	1245	WP_003632052.1	6-phosphofructokinase	-
GCB94_RS07385 (GCB94_07355)	letS	1446413..1449148 (-)	2736	WP_085956275.1	response regulator	Regulator
GCB94_RS07390 (GCB94_07360)	gltX	1449277..1450692 (+)	1416	WP_003632050.1	glutamate--tRNA ligase	-
GCB94_RS07395 (GCB94_07365)	-	1450689..1451963 (+)	1275	WP_003632048.1	serine hydrolase domain-containing protein	-
GCB94_RS07400 (GCB94_07370)	-	1452103..1453086 (+)	984	WP_003632046.1	hypothetical protein	-
GCB94_RS07405 (GCB94_07375)	gstA	1453145..1453747 (+)	603	WP_003632045.1	glutathione transferase GstA	-

Sequence

Protein

• Length: 911 a.a.
• Molecular weight: 102825.48 Da
• Isoelectric Point: 7.7707

>NTDB_id=393314 GCB94_RS07385 WP_085956275.1 1446413..1449148(-) (letS) [Legionella longbeachae strain B1445CHC]
MLKSIGIKYQLRITTLIPVFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRGDDRTLQGLINASTINP
EVKALAFYSSDGQLLAYRGGKHSLNKPFTAPKFTGDYIKSKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMASRADD
ILGWLSLDIDTRSMIIKRYQMLIVTIFITLFGLLVGLTIHYFLSKQIYLPISRLRRSMKQILRNEFETEIKTTSSGELGI
IEQGCSHLQKKHLETIRDLNHHIEVATADLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLALAAPNAHKKGIDLIPITE
LNVPKIVLGDPFRVKQFISNLVTNAVKFTDHGYVLIRTNVEQETEKDYTLCITITDTGLGISPEDQSKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMKGRITFASELNKGSVFTAYIKVEKLVAYEVERNQVHPFAHFKMLCFDDNPMQLEALCNG
LGYWGIKCIAVSSLNQLAKELKDNKDCQIAFLNINKGYEQQITKLIAEHNYFPYVLISKWLINDYAALGAQGFLYKPISI
QKLQDIIESLTNQENIEKSVNHELEGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTRSNITSVDNGEIAVSVCNEKKFS
LILLDLRMPKINGLEAARLIRQKSEFNRHTPIVLISANGRDVNDIDLKKAGVNFCLQKPIDEKQLLIQILRIADKAKHSA
IDWQLCIQKASGNQSLAEEFLARFVEELLKNREEFIQLMHEKNVKQLGEVAHKLHGACCFSGVPTLQKKVVQVEKLAAHA
ASIEELAMPFAELIQSIDAVISEYENQKIKT

Nucleotide

• Length: 2736 bp

>NTDB_id=393314 GCB94_RS07385 WP_085956275.1 1446413..1449148(-) (letS) [Legionella longbeachae strain B1445CHC]
ATCTTGAAAAGCATTGGTATAAAGTATCAACTACGAATTACTACTTTAATTCCTGTTTTTCTCGTCGCCCTACTCCTTGC
CATTTTTTATAATGGGTTGTTTGGTAATGACTTAAAACAACACATGTCTCGCCTTGGTGAAGCATATATCCGGCAATTAC
TTCCGGCTGCCCAGTATGCTATGCTGCGTGGGGACGATCGAACCTTACAAGGCCTAATCAATGCCTCTACAATCAACCCC
GAAGTTAAAGCACTTGCTTTTTATAGTAGCGACGGTCAACTCCTTGCTTATCGTGGTGGCAAACATTCGCTTAACAAACC
ATTTACTGCACCTAAATTCACCGGGGATTACATCAAAAGTAAACAAATTAACCCCTTTACTATTAATTTTATCGCGCCGG
TTACGATTCCAAAATTCAATTTGTATTCCAATTCTTCTTTTAAAAATATTTTAAGTCCCATGGCATCCCGTGCTGATGAC
ATTCTTGGGTGGTTGTCTCTTGATATTGATACTCGTTCAATGATAATCAAACGTTATCAGATGCTTATTGTCACTATTTT
CATTACTTTATTTGGGTTATTAGTAGGATTAACCATTCACTACTTTCTCTCCAAACAAATTTATTTACCTATTTCTCGTT
TACGACGAAGCATGAAACAAATTTTGCGTAACGAGTTTGAAACAGAAATAAAAACAACAAGCTCTGGTGAATTAGGCATA
ATTGAACAGGGATGTTCCCATTTGCAAAAAAAACACCTTGAAACGATACGTGATCTAAACCACCACATTGAGGTAGCCAC
GGCTGATTTACAACAAAGTTTGGAACTCTTGGAAGAAAAAAATATTGAACTCTCCCTCGAAAAGAAAAAAATTGAAGAAA
AAAGTCGGCAAAAATCTGAGTTCATAGCCAATATGAGCCATGAAATTCGTACGCCGATGAATGGAGTTATTGGTTTTACT
AACGTTTTGCTTGAAAGTAAACTCGATCCATTACAACTGGATTATGTAAAAACAATTAAATCATCAGCACAAGACTTATT
AGGGATTATCAATGATATTCTCGATTTCTCAAAAATTGATGCAGGAAAACTTCATCTCGATTGTATTCCGTTAAATATTC
GCCATTGTATTGATGAAGTACTCGCTCTTGCAGCACCTAATGCCCATAAGAAGGGAATCGACTTAATTCCTATAACAGAA
CTAAACGTACCTAAAATTGTTTTAGGGGATCCCTTCAGGGTGAAACAATTCATTAGCAACCTGGTAACTAATGCTGTTAA
ATTTACCGATCATGGATATGTATTAATCCGTACCAATGTGGAGCAGGAAACGGAAAAAGATTACACTTTATGCATTACAA
TTACTGATACAGGCCTAGGTATTTCTCCTGAAGACCAAAGCAAATTATTTACAGCCTTCAATCAAGCAGATACAAGTATT
ACCCGTCGTTATGGGGGCTCCGGACTTGGCTTGGTAATTTGCAAAAAACTCTGCGAGGAAATGAAAGGCCGTATTACTTT
CGCCAGCGAACTCAACAAAGGTTCTGTATTTACCGCTTATATCAAGGTTGAAAAATTGGTTGCTTATGAAGTTGAAAGAA
ATCAAGTGCATCCTTTTGCGCATTTCAAAATGCTTTGTTTTGACGATAACCCAATGCAATTGGAAGCCCTGTGTAATGGC
TTAGGATATTGGGGAATAAAATGTATCGCTGTAAGTTCACTCAATCAACTCGCGAAAGAGCTGAAAGACAATAAAGACTG
CCAAATCGCATTTCTTAATATCAATAAAGGCTACGAACAGCAAATTACCAAGCTAATAGCCGAACATAATTATTTTCCCT
ATGTATTAATCTCTAAATGGCTTATCAATGATTATGCAGCACTTGGAGCACAGGGATTTTTATATAAACCCATTAGCATC
CAAAAACTCCAAGATATTATTGAGTCATTAACAAATCAGGAAAATATTGAAAAGTCGGTTAACCATGAATTAGAAGGTTT
AAGGGAACAATTACGTTTCTTACATCCTGATCTTCTTATAGCTGAAGATAATCCAGTAAATAAAATGCTTCTTGATTCTT
TATTAGGGACTCGTTCCAACATTACATCCGTTGATAATGGCGAAATAGCCGTATCGGTGTGTAATGAAAAGAAATTCAGT
CTCATCTTGCTTGATTTGCGTATGCCTAAAATAAATGGCTTGGAAGCTGCTCGACTTATCCGCCAAAAATCAGAGTTTAA
TCGTCATACACCAATAGTATTGATTAGTGCAAATGGTAGAGATGTTAATGATATTGATTTAAAGAAAGCTGGTGTAAATT
TTTGTTTGCAAAAGCCTATAGACGAAAAACAATTATTAATTCAAATTTTACGTATTGCAGATAAAGCAAAACACTCAGCA
ATAGATTGGCAACTATGTATTCAAAAAGCCTCAGGAAATCAATCACTTGCTGAAGAGTTTCTTGCTCGGTTTGTAGAAGA
ATTGCTTAAAAATCGTGAAGAGTTTATCCAATTAATGCATGAAAAAAATGTGAAGCAACTGGGCGAAGTGGCGCATAAAC
TTCATGGAGCATGTTGTTTTAGTGGTGTTCCCACGTTACAAAAAAAAGTAGTTCAGGTTGAAAAACTTGCTGCGCATGCT
GCTTCAATCGAAGAGTTAGCTATGCCTTTCGCAGAATTAATTCAAAGCATCGATGCGGTGATTAGTGAATACGAAAATCA
AAAAATAAAAACTTAG

Domains

Predicted by InterproScan.

• Single cache domain 4 (sCache_4) (36-180)

• Hpt domain (Hpt) (819-900)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• Response regulator receiver domain (Response_reg) (679-787)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	78.06	99.561	0.777