Detailed information    

insolico Bioinformatically predicted

Overview

Name   comK/comK1   Type   Regulator
Locus tag   D5R78_RS09580 Genome accession   NZ_CP045187
Coordinates   1979560..1980144 (+) Length   194 a.a.
NCBI ID   WP_011276196.1    Uniprot ID   A0A2A1KAP4
Organism   Staphylococcus haemolyticus strain VB19458     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1980673..1987744 1979560..1980144 flank 529
IScluster/Tn 1980673..1987744 1979560..1980144 flank 529


Gene organization within MGE regions


Location: 1979560..1987744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D5R78_RS09580 (D5R78_004930) comK/comK1 1979560..1980144 (+) 585 WP_011276196.1 competence protein ComK Regulator
  D5R78_RS09595 (D5R78_004915) - 1980673..1981988 (+) 1316 Protein_1897 ISL3 family transposase -
  D5R78_RS09600 (D5R78_004910) - 1982487..1982960 (+) 474 WP_011276199.1 PH domain-containing protein -
  D5R78_RS09605 (D5R78_004905) - 1983031..1983606 (+) 576 WP_011276200.1 hypothetical protein -
  D5R78_RS09610 (D5R78_004900) - 1983694..1983777 (+) 84 WP_227528431.1 Ltp family lipoprotein -
  D5R78_RS09615 (D5R78_004895) - 1983825..1984814 (-) 990 WP_037569657.1 lipoate--protein ligase -
  D5R78_RS09620 (D5R78_004890) - 1985015..1985191 (+) 177 WP_011276202.1 YkvS family protein -
  D5R78_RS09625 (D5R78_004885) - 1985208..1985810 (+) 603 WP_011276203.1 type II CAAX prenyl endopeptidase Rce1 family protein -

Sequence

Protein


Download         Length: 194 a.a.        Molecular weight: 23002.43 Da        Isoelectric Point: 9.2942

>NTDB_id=392531 D5R78_RS09580 WP_011276196.1 1979560..1980144(+) (comK/comK1) [Staphylococcus haemolyticus strain VB19458]
MTNISQSQNTVYIIRKGDMIIKPVIDDYEQTKGSEIWKYDSTIVSSPFKTQKIVERSCKFYGNSYISKKSETQRIAGITS
KPPILLTPLFPTYFFPTHSDRLEENMWINMHYVHEIKPLKNRKCKIIFANHQTLTLNVSYHSIWHQYSNCIFYYYMVDKQ
SRMKSNNPEMPIDYEKTTLNIFEALSHYSLLQDK

Nucleotide


Download         Length: 585 bp        

>NTDB_id=392531 D5R78_RS09580 WP_011276196.1 1979560..1980144(+) (comK/comK1) [Staphylococcus haemolyticus strain VB19458]
ATGACAAATATTTCTCAAAGCCAAAATACTGTATATATTATTCGAAAAGGAGATATGATAATCAAACCCGTCATTGATGA
TTATGAGCAAACAAAAGGATCAGAAATATGGAAATATGATTCCACAATAGTTTCAAGCCCATTCAAAACTCAAAAAATCG
TCGAACGCTCATGTAAATTTTATGGTAATAGCTATATTAGTAAGAAATCCGAAACACAACGAATTGCCGGCATTACTAGT
AAACCACCTATTTTATTGACTCCTCTCTTCCCCACTTATTTTTTCCCTACGCATTCAGACCGTTTAGAAGAAAACATGTG
GATTAATATGCATTATGTACATGAAATTAAACCTCTTAAAAATCGAAAATGTAAAATTATTTTTGCAAATCATCAAACAT
TAACACTTAATGTTTCCTACCACAGTATTTGGCACCAATACTCTAACTGCATTTTTTATTATTACATGGTCGATAAACAA
TCTCGTATGAAGTCAAACAATCCAGAAATGCCAATAGATTATGAGAAAACGACTTTAAATATTTTCGAAGCACTTTCACA
TTATTCACTATTACAAGATAAATAG

Domains

Predicted by InterproScan.

ComK protein (ComK)

(11-161)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A1KAP4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comK/comK1 Staphylococcus aureus MW2

68.617

96.907

0.665
  comK/comK1 Staphylococcus aureus N315

68.617

96.907

0.665

Multiple sequence alignment