Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HO400_RS11735 Genome accession   NZ_CP053597
Coordinates   2495499..2497331 (+) Length   610 a.a.
NCBI ID   WP_001283424.1    Uniprot ID   B1IZZ1
Organism   Escherichia coli strain T7Express_LysY     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2490499..2502331
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HO400_RS11705 (HO400_11710) hiuH 2490830..2491243 (-) 414 WP_000920127.1 hydroxyisourate hydrolase -
  HO400_RS11710 (HO400_11715) hprR 2491376..2492047 (+) 672 WP_001339045.1 response regulator transcription factor HprR -
  HO400_RS11715 (HO400_11720) hprS 2492047..2493405 (+) 1359 WP_000826748.1 two-component system sensor histidine kinase HprS -
  HO400_RS11720 (HO400_11725) hchA 2493513..2494157 (-) 645 Protein_2293 glyoxalase III HchA -
  HO400_RS11730 (HO400_11735) uvrY 2494927..2495502 (+) 576 Protein_2295 UvrY/SirA/GacA family response regulator transcription factor -
  HO400_RS11735 (HO400_11740) uvrC 2495499..2497331 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  HO400_RS11740 (HO400_11745) pgsA 2497388..2497936 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  HO400_RS11760 (HO400_11765) yecA 2498585..2499250 (+) 666 WP_000847880.1 UPF0149 family protein YecA -
  HO400_RS11765 (HO400_11770) tyrP 2499312..2500523 (-) 1212 WP_000797573.1 tyrosine transporter TyrP -
  HO400_RS11770 (HO400_11775) yecH 2500713..2500952 (+) 240 WP_000377224.1 YecH family metal-binding protein -
  HO400_RS11775 (HO400_11780) ftnA 2500990..2501487 (-) 498 WP_000917208.1 non-heme ferritin -
  HO400_RS11780 (HO400_11785) yecR 2501659..2501982 (-) 324 WP_001237875.1 YecR-like lipofamily protein -
  HO400_RS11785 (HO400_11790) azuC 2502245..2502331 (+) 87 WP_010723106.1 stress response protein AzuC -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68216.09 Da        Isoelectric Point: 9.3685

>NTDB_id=392252 HO400_RS11735 WP_001283424.1 2495499..2497331(+) (uvrC) [Escherichia coli strain T7Express_LysY]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGVDRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=392252 HO400_RS11735 WP_001283424.1 2495499..2497331(+) (uvrC) [Escherichia coli strain T7Express_LysY]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATCGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTTACAGCACTTGCCAGTGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGTAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACACGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B1IZZ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374