Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HFELIS_RS02660 Genome accession   NC_014810
Coordinates   522566..523318 (+) Length   250 a.a.
NCBI ID   WP_013468994.1    Uniprot ID   -
Organism   Helicobacter felis ATCC 49179     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 517566..528318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HFELIS_RS02645 (HFELIS_05380) nusA 517723..518853 (+) 1131 WP_013468991.1 transcription termination factor NusA -
  HFELIS_RS02650 (HFELIS_05390) - 518850..520154 (-) 1305 WP_013468992.1 anaerobic C4-dicarboxylate transporter -
  HFELIS_RS02655 (HFELIS_05400) comB4 520167..522509 (-) 2343 WP_013468993.1 TraM recognition domain-containing protein Machinery gene
  HFELIS_RS02660 (HFELIS_05410) comB8 522566..523318 (+) 753 WP_013468994.1 VirB8/TrbF family protein Machinery gene
  HFELIS_RS02665 (HFELIS_05420) - 523311..524102 (-) 792 WP_013468995.1 hypothetical protein -
  HFELIS_RS02670 (HFELIS_05430) - 524187..525206 (+) 1020 WP_013468996.1 VirB6 type IV secretion protein -
  HFELIS_RS02675 - 525398..525586 (-) 189 WP_041302731.1 SEL1-like repeat protein -
  HFELIS_RS02680 (HFELIS_05450) - 525604..526023 (-) 420 WP_013468998.1 sel1 repeat family protein -
  HFELIS_RS02685 (HFELIS_05460) - 526036..526845 (-) 810 WP_013468999.1 tetratricopeptide repeat protein -
  HFELIS_RS02690 (HFELIS_05470) - 526903..527955 (-) 1053 WP_013469000.1 restriction endonuclease -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 28885.17 Da        Isoelectric Point: 9.0415

>NTDB_id=39170 HFELIS_RS02660 WP_013468994.1 522566..523318(+) (comB8) [Helicobacter felis ATCC 49179]
MRDDFLREQLLKELLERLEARQAQFEEEIKTKIDGFNFKHMDLNSVFRLERKHTAIAYKLVALLSVISLSLAIAIVVLLP
LKETQHHFIDFANQDKHYAIIQRADGSISSNEALVRSLIGHYILNRESINGIDDQERYEIVRLQSSSKVWRLFEELVASK
NSVYTDSKIQRDIQIIHIAILEGVQGSKISHVQIKAKLFHEGKPVYEKRYNITLSYAFVSPPKSDNTPLPKNPTGFQVTQ
YSVTQMQDFK

Nucleotide


Download         Length: 753 bp        

>NTDB_id=39170 HFELIS_RS02660 WP_013468994.1 522566..523318(+) (comB8) [Helicobacter felis ATCC 49179]
ATGAGAGATGATTTTCTGCGTGAACAACTTTTAAAAGAACTCTTGGAGCGTTTGGAGGCTAGACAAGCTCAATTTGAAGA
AGAGATCAAGACTAAGATCGATGGTTTTAACTTTAAGCACATGGATTTAAACAGCGTCTTTAGATTGGAGCGCAAACACA
CCGCGATTGCCTATAAGCTCGTGGCTTTGTTGAGTGTGATTAGTCTAAGTCTAGCGATTGCCATCGTTGTTCTTCTGCCC
CTCAAGGAAACCCAACACCATTTTATAGATTTTGCTAACCAAGACAAGCATTACGCCATTATCCAGCGCGCTGATGGAAG
TATTTCAAGCAATGAGGCTCTTGTGCGCTCTCTTATTGGGCATTATATCCTCAATCGCGAGTCCATTAATGGGATTGATG
ATCAAGAACGCTATGAGATCGTGCGTCTGCAAAGCAGTAGCAAGGTGTGGCGACTTTTTGAGGAATTGGTCGCCTCTAAA
AATAGTGTTTACACGGACAGCAAAATCCAGCGAGATATTCAAATTATCCACATCGCTATTTTAGAGGGGGTGCAGGGCTC
TAAAATTAGCCATGTGCAAATCAAGGCCAAGCTTTTCCATGAGGGCAAACCTGTTTATGAAAAACGATATAACATCACCC
TAAGCTACGCTTTTGTGTCCCCTCCCAAGTCTGACAACACCCCCCTACCCAAAAACCCTACAGGTTTTCAGGTTACCCAA
TACAGCGTTACTCAAATGCAGGATTTCAAGTAA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(51-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

56.198

96.8

0.544

Multiple sequence alignment