Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   HFELIS_RS02655 Genome accession   NC_014810
Coordinates   520167..522509 (-) Length   780 a.a.
NCBI ID   WP_013468993.1    Uniprot ID   E7AA52
Organism   Helicobacter felis ATCC 49179     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 515167..527509
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HFELIS_RS02640 (HFELIS_05370) - 516388..517659 (+) 1272 WP_013468990.1 HP0729 family protein -
  HFELIS_RS02645 (HFELIS_05380) nusA 517723..518853 (+) 1131 WP_013468991.1 transcription termination factor NusA -
  HFELIS_RS02650 (HFELIS_05390) - 518850..520154 (-) 1305 WP_013468992.1 anaerobic C4-dicarboxylate transporter -
  HFELIS_RS02655 (HFELIS_05400) comB4 520167..522509 (-) 2343 WP_013468993.1 TraM recognition domain-containing protein Machinery gene
  HFELIS_RS02660 (HFELIS_05410) comB8 522566..523318 (+) 753 WP_013468994.1 VirB8/TrbF family protein Machinery gene
  HFELIS_RS02665 (HFELIS_05420) - 523311..524102 (-) 792 WP_013468995.1 hypothetical protein -
  HFELIS_RS02670 (HFELIS_05430) - 524187..525206 (+) 1020 WP_013468996.1 VirB6 type IV secretion protein -
  HFELIS_RS02675 - 525398..525586 (-) 189 WP_041302731.1 SEL1-like repeat protein -
  HFELIS_RS02680 (HFELIS_05450) - 525604..526023 (-) 420 WP_013468998.1 sel1 repeat family protein -
  HFELIS_RS02685 (HFELIS_05460) - 526036..526845 (-) 810 WP_013468999.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 780 a.a.        Molecular weight: 88922.23 Da        Isoelectric Point: 8.3539

>NTDB_id=39169 HFELIS_RS02655 WP_013468993.1 520167..522509(-) (comB4) [Helicobacter felis ATCC 49179]
MWHRLGNFLRTKAWDFLTGTFPKVYSMTEENNILGLYDAHFILTKQEQLVGMVEIEGLSLSAMSKEDLEGYFESKHHALS
QLDGVILRIYTKRRRVLLEQNPCVQNAHAQAIIQSFESKAIYETRYYLIFETITKPIQGFFATKKLQLTTAEDQPYAHKL
SLLNQAIAQIRHTLASFKPTLLSGREVLEFYASYINGVSLPLKPSQGFLEDSYIATNVHFHQNYFVQERHNTRIYNCIIG
IKAYGSQTITSIALSTLLHHQKELDIIFSIKPLSTQEALAFLQEKIRLTFTKLVRAELENYYELIKAKRLCLQQCALNIH
LKSPDLETLNQHAQEVLSLLANEHLVGVVETLGLKPAYFSFFPGRMHLNPRLRYQSAQALACLVVFERFNRGFKSNSWGN
MPLSVFKNLDHSAYLFNFHNQEVRHLGVAKHNIAKVNGHTMIIGATGAGKTTLMGFLMMSALKYDHLNILALDRAYGLFS
CTQYLGGNYNSGAHFKINPLSLEYSQENHDFLHSFYQAMLNLTPQDIAENNAIHKALHSLYSTLPPKTFSLQDFKETLIH
NSKLALALESYCNHPLFSALEDSLELNNPLTTINMDAITLNPKDLGLLAYYIFYKLFHLSLHANRGFLLFVDEFRSYAQN
PSLNAHINTLITQARKANGVVVLALQDIHQLAQMQDAKSFLKNMGTLIIYPQKHAQDLSSELGVALSQMERHFLETTPLH
ARQVLIKNMNDGSSNIVDVNLEALGPYLQIFNSNATHARYLEELMRAHPQTWRTHLLKQT

Nucleotide


Download         Length: 2343 bp        

>NTDB_id=39169 HFELIS_RS02655 WP_013468993.1 520167..522509(-) (comB4) [Helicobacter felis ATCC 49179]
ATGTGGCATAGGTTAGGCAATTTTTTACGCACCAAAGCTTGGGATTTTTTAACCGGCACCTTCCCCAAAGTCTATTCTAT
GACTGAGGAAAACAATATTTTGGGGCTTTATGATGCGCACTTTATCCTCACCAAACAAGAGCAATTAGTGGGCATGGTAG
AAATTGAGGGTTTGAGTTTGAGTGCTATGAGCAAGGAGGATTTAGAGGGCTATTTTGAGAGCAAGCACCATGCCTTAAGC
CAGCTTGATGGGGTGATTTTGCGCATTTACACCAAACGCCGCCGTGTTCTTTTGGAACAAAACCCTTGCGTGCAAAATGC
GCACGCCCAAGCCATTATCCAAAGCTTTGAGAGCAAAGCGATCTATGAGACACGCTATTATTTAATCTTTGAAACCATCA
CCAAGCCCATTCAAGGCTTTTTTGCGACAAAAAAACTCCAGCTCACTACTGCAGAGGATCAACCCTACGCGCACAAACTC
TCCCTTTTAAACCAAGCGATCGCACAAATCCGACACACGCTTGCCAGCTTTAAACCCACTCTTTTAAGTGGTCGCGAGGT
CCTTGAGTTTTACGCTTCTTATATCAATGGGGTTAGTCTTCCTCTCAAGCCCTCGCAGGGTTTTTTAGAGGATAGCTATA
TCGCCACTAATGTGCATTTTCATCAAAATTACTTTGTGCAAGAGAGGCACAACACGCGCATTTATAATTGTATTATTGGG
ATTAAGGCATATGGGAGTCAAACCATCACTTCTATAGCCCTCTCTACCTTGCTCCATCACCAAAAAGAGTTAGACATTAT
CTTTTCAATCAAGCCTCTGAGCACTCAAGAAGCCCTAGCCTTCCTCCAAGAGAAAATCCGCCTCACCTTTACAAAGCTGG
TGCGTGCAGAGTTAGAAAATTACTATGAGCTCATCAAGGCTAAACGCCTCTGTTTGCAACAATGCGCGCTCAATATCCAT
CTTAAAAGCCCGGATTTAGAAACCTTAAACCAACACGCCCAAGAGGTGTTGAGTTTGTTAGCTAATGAACACTTAGTCGG
CGTGGTAGAAACTTTGGGCTTGAAACCGGCGTATTTTTCTTTTTTCCCGGGGCGCATGCATCTTAATCCAAGATTGCGTT
ATCAAAGCGCGCAGGCTTTGGCATGTTTGGTGGTGTTTGAGCGATTCAATCGGGGTTTTAAAAGCAATTCTTGGGGGAAT
ATGCCCTTAAGTGTGTTTAAGAATTTGGATCACTCTGCCTATCTCTTTAATTTTCATAACCAAGAAGTGCGCCATTTAGG
CGTAGCCAAACACAATATCGCTAAGGTGAATGGGCACACGATGATCATCGGAGCGACTGGGGCGGGCAAAACTACTTTGA
TGGGGTTTTTGATGATGAGCGCGCTCAAATACGATCATCTCAACATTCTAGCCCTCGATCGCGCCTATGGTCTTTTCTCT
TGCACGCAGTATCTTGGAGGGAATTACAATAGCGGGGCGCATTTTAAAATCAACCCGCTTTCTTTAGAATATTCCCAAGA
AAATCACGACTTTTTGCACTCCTTTTATCAAGCCATGCTCAATCTAACGCCCCAAGACATCGCAGAAAACAACGCCATTC
ATAAGGCTTTGCATAGCCTCTATTCTACTCTACCCCCCAAAACCTTTAGCCTTCAAGATTTTAAAGAAACTCTGATTCAT
AACTCTAAACTCGCTCTAGCTTTAGAGTCCTATTGTAACCACCCCCTTTTTAGTGCCCTAGAGGATAGCCTAGAGCTTAA
CAACCCTCTAACCACGATCAACATGGACGCTATCACCCTCAACCCTAAGGATTTAGGACTTTTAGCCTATTACATCTTTT
ATAAACTTTTTCATCTGTCCTTGCATGCCAATCGGGGGTTTTTATTGTTCGTGGATGAGTTTAGAAGTTACGCTCAAAAT
CCAAGCCTCAATGCCCACATCAATACCCTCATCACACAAGCGCGTAAGGCAAATGGGGTTGTGGTGCTCGCTCTCCAAGA
CATCCATCAGCTCGCACAAATGCAAGATGCCAAGAGTTTTCTAAAAAACATGGGCACTTTGATCATTTACCCTCAAAAAC
ATGCCCAAGACTTGAGCTCTGAGCTAGGTGTTGCTCTCAGCCAAATGGAGAGGCATTTTTTAGAAACCACCCCCCTACAC
GCGCGCCAAGTTTTGATCAAAAACATGAATGATGGGAGTTCTAATATTGTAGATGTCAATCTTGAAGCCTTAGGACCTTA
TTTACAAATCTTTAATTCTAATGCCACTCATGCCAGATATTTAGAAGAGCTTATGCGCGCCCACCCTCAAACTTGGCGCA
CCCATTTGCTCAAACAAACTTAA

Domains

Predicted by InterproScan.

TraM recognition site of TraD and TraG (TraG-D_C)

(628-705)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(177-371)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E7AA52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

51.838

100

0.524

Multiple sequence alignment