Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   LKK75_RS10160 Genome accession   NZ_CP045033
Coordinates   2046800..2048596 (+) Length   598 a.a.
NCBI ID   WP_013854784.1    Uniprot ID   A0AAX3UD09
Organism   Lactobacillus kefiranofaciens subsp. kefiranofaciens strain LKK75     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2041800..2053596
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LKK75_RS10135 (LKK75_10135) - 2042032..2043573 (-) 1542 WP_013854779.1 ABC-F family ATP-binding cassette domain-containing protein -
  LKK75_RS10140 (LKK75_10140) - 2043580..2043951 (-) 372 WP_025084257.1 hypothetical protein -
  LKK75_RS10145 (LKK75_10145) - 2044097..2044675 (+) 579 WP_013854781.1 GNAT family N-acetyltransferase -
  LKK75_RS10150 (LKK75_10150) - 2044650..2045339 (-) 690 WP_013854782.1 DUF554 domain-containing protein -
  LKK75_RS10155 (LKK75_10155) - 2045409..2046638 (-) 1230 WP_013854783.1 LCP family protein -
  LKK75_RS10160 (LKK75_10160) pepF 2046800..2048596 (+) 1797 WP_013854784.1 oligoendopeptidase F Regulator
  LKK75_RS10165 (LKK75_10165) - 2048662..2048832 (-) 171 WP_264298011.1 bacteriocin immunity protein -
  LKK75_RS10170 (LKK75_10170) - 2048870..2049067 (-) 198 WP_013854786.1 helix-turn-helix transcriptional regulator -
  LKK75_RS10175 (LKK75_10175) - 2049064..2049540 (-) 477 WP_013854787.1 hypothetical protein -
  LKK75_RS10180 (LKK75_10180) - 2050237..2051337 (+) 1101 WP_013854789.1 vitamin B12 independent methionine synthase -
  LKK75_RS10185 (LKK75_10185) - 2051400..2051876 (+) 477 WP_013854790.1 S-ribosylhomocysteine lyase -
  LKK75_RS10190 (LKK75_10190) - 2052006..2052293 (+) 288 WP_013854791.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  LKK75_RS10195 (LKK75_10195) - 2052277..2052540 (+) 264 WP_013854792.1 Txe/YoeB family addiction module toxin -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68208.10 Da        Isoelectric Point: 4.7338

>NTDB_id=391373 LKK75_RS10160 WP_013854784.1 2046800..2048596(+) (pepF) [Lactobacillus kefiranofaciens subsp. kefiranofaciens strain LKK75]
MAIPTRDEVPAELKWDLTRIFKTDQDWEQAYDDTKQEVAELDQLKGSLAKSGQDLYEGLTKILAVRRKVENIYVYATMSS
DVDTANSHYLGYVSRVQSLANQFEAVTSFISPEILSIPEDKFKQFLQAEPRLKNYAHYLETITNKRPHTLPAEEEKIIAD
AGDALSTSENTFNVLTNSDMEYGYVQDDDGNMEQLSDGLYSLLIQSQNRDVRKGAFDTLYTTYGQFQNSLASTLSGVVKK
HNYNARVHKYNSAREAALAENGVPTKVYDTLIQEVDSHLDLLHRYVALRKKILGLKDLQMWDMYVPLTGKPSLSYNFKEA
KEVAKKALAPLGEDYLKHVDYIFNNRVIDSVENKNKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYTR
HTQPYIYGEYPIFVAEIASTTNENILTEYFLGHITDPKTRAFILNYYLDSFKGTLFRQTQFAVFEQFLHEADAKGEPLTA
DTLDEVYGQINQHYYGDAVEPGGDIALEWSRIPHFYYNFYVYQYATGFAAATALANKVVHGTTAERDAYLGFLKAGSSDY
PTEIMKHAGVDMTKPDYLEDAFKTFEKRLDEFESLIEK

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=391373 LKK75_RS10160 WP_013854784.1 2046800..2048596(+) (pepF) [Lactobacillus kefiranofaciens subsp. kefiranofaciens strain LKK75]
ATGGCAATACCAACTAGAGATGAAGTCCCAGCAGAACTTAAATGGGACTTGACGAGAATTTTTAAGACAGATCAAGATTG
GGAGCAGGCTTACGACGACACTAAACAAGAAGTAGCTGAACTTGATCAATTAAAAGGATCATTAGCTAAGTCGGGACAAG
ATTTATACGAAGGCTTAACCAAGATCTTAGCAGTTAGACGCAAGGTAGAAAATATCTACGTTTATGCCACTATGTCTAGT
GATGTCGATACCGCTAATTCACACTACTTAGGCTATGTTAGCCGGGTGCAGAGTTTGGCTAATCAATTCGAAGCCGTAAC
CAGCTTTATTAGTCCAGAAATCTTGAGCATCCCAGAAGACAAGTTCAAGCAATTTTTGCAAGCTGAACCACGCTTAAAGA
ATTACGCTCACTACTTGGAAACGATCACTAATAAGCGGCCCCATACTTTACCAGCTGAGGAAGAAAAAATTATTGCCGAT
GCCGGGGATGCCTTAAGCACTTCAGAGAACACTTTCAATGTTTTAACCAACTCCGACATGGAATACGGCTACGTGCAAGA
TGACGACGGCAATATGGAACAGTTGTCTGATGGGCTTTATTCATTATTGATTCAGTCACAGAACCGTGACGTCAGAAAAG
GTGCCTTTGACACGCTCTATACAACATATGGTCAATTTCAAAACTCCTTAGCTTCTACTCTTTCCGGCGTAGTCAAGAAG
CACAACTATAACGCTCGCGTGCACAAGTATAATTCGGCACGTGAAGCCGCATTAGCTGAAAACGGCGTACCAACCAAGGT
TTACGACACTTTGATTCAAGAAGTTGATTCACACCTTGACCTGCTTCACCGTTATGTTGCGCTGCGTAAGAAAATTTTAG
GCTTGAAAGATTTACAAATGTGGGACATGTACGTGCCGCTAACGGGTAAGCCATCACTGTCCTACAATTTTAAGGAAGCA
AAAGAAGTTGCCAAGAAGGCCTTGGCCCCACTTGGTGAAGACTACTTGAAGCATGTCGATTATATTTTTAATAACCGCGT
GATCGACAGCGTGGAAAATAAAAACAAGGTGACTGGTGCTTACTCTGGTGGTGCTTACGACACTGACCCATATGAACTGC
TCAACTGGGAAGACAATATTGATTCACTTTACACTTTAGTTCACGAAACCGGTCACTCCGTTCACTCTTGGTATACGCGT
CATACCCAGCCTTACATCTATGGCGAGTATCCGATCTTCGTGGCTGAGATTGCTTCAACGACGAACGAAAATATTTTGAC
CGAATATTTCCTGGGGCATATTACCGATCCGAAGACGCGGGCCTTTATTCTGAACTACTACCTTGACTCATTCAAGGGCA
CGCTGTTCCGTCAAACGCAATTCGCTGTTTTTGAACAATTCTTGCATGAAGCTGATGCCAAAGGCGAACCATTAACTGCC
GATACTCTGGATGAGGTTTATGGACAAATCAACCAGCACTACTACGGTGATGCGGTTGAACCCGGCGGCGATATTGCCTT
AGAGTGGTCACGAATTCCGCACTTCTACTACAACTTCTACGTTTACCAATATGCGACGGGCTTTGCGGCTGCGACTGCTT
TGGCTAACAAGGTAGTACATGGAACAACGGCGGAGAGGGATGCCTACCTTGGCTTCCTTAAGGCTGGATCTAGCGATTAC
CCAACAGAGATCATGAAGCACGCTGGCGTGGACATGACTAAGCCGGATTACTTGGAAGATGCATTTAAGACTTTTGAAAA
GCGCTTGGATGAATTTGAGAGTTTGATTGAGAAGTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(113-181)

Peptidase family M3 (Peptidase_M3)

(203-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

50.59

99.164

0.502

Multiple sequence alignment